Results 91 to 100 of about 28,880 (211)
Excitable dynamics through toxin-induced mRNA cleavage in bacteria.
PLoS ONE, 2019 Toxin-antitoxin (TA) systems in bacteria and archaea are small genetic elements consisting of the genes coding for an intracellular toxin and an antitoxin that can neutralize this toxin. In various cases, the toxins cleave the mRNA.
Stefan Vet +2 more
doaj +1 more source
ChemMedChem, Volume 21, Issue 15, 14 August 2026.Temporins, among antimicrobial peptides, are short frog‐derived molecules with potent antibacterial activity. This review highlights chemical optimization strategies applied to temporins A–L, showing how sequence tuning modulates structure, stability, and selectivity, enabling improved activity against resistant pathogens.
Ida Boccino +2 more
wiley +1 more source
Identification and characterization of a toxin-antitoxin system in the pVir plasmid of Campylobacter jejuni [PDF]
, 2011 Toxin-antitoxin systems are prevalent in different bacterial organisms and are encoded in the chromosomal or plasmid DNA. The primary function of a plasmid toxin-antitoxin module is to stabilize the plasmid by eliminating plasmid-free daughter cells ...
Patil, Rocky
core +2 more sources
Tuning the expression of the bacterial relBE toxin–antitoxin system in Saccharomyces cerevisiae allows characterizing the subsequent growth inhibition [PDF]
, 2023 International audienceThe bacterial toxin–antitoxin systems are each composed of a toxin, which severely inhibits bacterial cells growth, and a specific neutralizing antitoxin.
Duperray, Maëlle +2 more
core +1 more source
Acta Paediatrica, Volume 115, Issue 8, Page 1646-1653, August 2026.ABSTRACT Aim To determine the clinico‐demographic profile and predictors of mortality in hospitalised children with diphtheria. Methods This retrospective cohort study included 202 children aged 5–16 years diagnosed with diphtheria per WHO criteria at Lady Reading Hospital, Peshawar, from January 2023 to December 2024. Data on demographics, vaccination
Amir Muhammad +6 more
wiley +1 more source
Investigation of activity of acinetobacter baumannii toxin-antitoxin system antitoxin. [PDF]
, 2016 Investigation of Activity of Acinetobacter baumannii Toxin-antitoxin System Antitoxin Acinetobacter baumannii is a gram negative opportunistic pathogen which causes variety of nosocomial infections.
Čepauskas, Albinas,
core
International Journal of Molecular Sciences, 2019 The toxin-antitoxin (TA) systems have been attracting attention due to their role in regulating stress responses in prokaryotes and their biotechnological potential. Much recognition has been given to type II TA system of mesophiles, while thermophiles have received merely limited attention.
Rawana Alkhalili +2 more
openaire +2 more sources
Toxin–antitoxin systems and regulatory mechanisms in Mycobacterium tuberculosis [PDF]
Pathogens and Disease, 2018 There has been a significant reduction in annual tuberculosis incidence since the World Health Organization declared tuberculosis a global health threat. However, treatment of M. tuberculosis infections requires lengthy multidrug therapeutic regimens to achieve a durable cure.
Richard A, Slayden +2 more
openaire +2 more sources
Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity
Advanced Science, Volume 13, Issue 37, 3 July 2026.This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley +1 more source
Current Protocols, Volume 6, Issue 7, July 2026.Abstract Viral metagenomics is an increasingly powerful tool for understanding the function and structure of viruses across the diverse environments of our planet. However, decoding the functional potential of prokaryotic viral metagenomes is extremely challenging.
George Bouras +6 more
wiley +1 more source