Results 111 to 120 of about 28,880 (211)

Identification of the First Functional Toxin-Antitoxin System in Streptomyces

PLoS ONE, 2012
Toxin-antitoxin (TA) systems are widespread among the plasmids and genomes of bacteria and archaea. This work reports the first description of a functional TA system in Streptomyces that is identical in two species routinely used in the laboratory: Streptomyces lividans and S. coelicolor.
Sevillano, Laura, Díaz, Margarita, Yamaguchi, Y., Inouye, M., Santamaría, Ramón I.   +4 more
openaire   +5 more sources

Genetic Toolbox Expansion Enables Constitutively Fluorescent Lacticaseibacillus rhamnosus for Functional Microbiome Research

Microbial Biotechnology, Volume 19, Issue 7, July 2026.
We expanded the genetic toolkit for Lacticaseibacillus rhamnosus by enabling direct cloning, and leveraging five constitutive promoters and a repressor system. Fluorescent L. rhamnosus strains with different fluorochromes engineered with the high‐performing PtlpA promoter demonstrated functionality in microbial competition assays, supporting microbiome
Ilke Van Tente, Marc Blanch‐Asensio, Tom Eilers, Dieter Vandenheuvel, Sarah Lebeer, Shrikrishnan Sankaran, Irina Spacova   +6 more
wiley   +1 more source

Toxin-Antitoxin Systems in the Mobile Genome of Acidithiobacillus ferrooxidans

PLoS ONE, 2014
Toxin-antitoxin (TA) systems are genetic modules composed of a pair of genes encoding a stable toxin and an unstable antitoxin that inhibits toxin activity. They are widespread among plasmids and chromosomes of bacteria and archaea. TA systems are known to be involved in the stabilization of plasmids but there is no consensus about the function of ...
Bustamante, Paula, Tello, Mario, Orellana, Omar   +2 more
openaire   +7 more sources

Keeping the wolves at bay: antitoxins of prokaryotic type II toxin-antitoxin systems

Frontiers in Molecular Biosciences, 2016
In their initial stages of discovery, prokaryotic toxin-antitoxin (TA) systems were confined to bacterial plasmids where they function to mediate the maintenance and stability of usually low- to medium-copy number plasmids through the post-segregational ...
Wai Ting eChan, Manuel eEspinosa, Chew Chieng eYeo   +2 more
doaj   +1 more source

Exploring the Potential of Zero‐Dimensional Carbon Nanomaterials in Photoluminescent, Electrochemiluminescent and Electrochemical Sensors

Advanced Materials Interfaces, Volume 13, Issue 11, 9 June 2026.
Zero‐dimensional carbon nanomaterials are presented as multifunctional platforms linking structure, property, and sensing performance. Surface engineering and heteroatom doping modulate electron‐transfer and luminescent behavior, enabling electrochemical, photoluminescent, and electrochemiluminescent detection. Fundamental design principles, analytical
Gustavo Martins, Jeferson Luiz Gogola, Ava Gevaerd, Cristiane Kalinke, Paulo Roberto de Oliveira, Fabio Roberto Caetano, Bruno Campos Janegitz, Márcio Fernando Bergamini, Luiz Humberto Marcolino‐Junior   +8 more
wiley   +1 more source

ORF43/ORF44: a possible Toxin-Antitoxin system in phiCh1 [PDF]

, 2016
Eine Sequenzanalyse des Genoms von phiCh1 zeigte eine Pin Domäne im ORF44 auf, ein Hinweis auf ein Typ II Toxin/Antitoxin System. In dieser Bachelorarbeit wurden die Auswirkungen von ORF43/44, einem möglichem Toxin/Antitoxin System im Virus phiCh1 ...
Lebhard, Jürgen
core  

Genomic epidemiology and lineage‐specific risk stratification of tet(X4)‐mediated tigecycline resistance along the pork production chain: A One Health perspective

iMetaOmics, Volume 3, Issue 2, June 2026.
Genome surveillance across a swine‐associated One Health continuum in China shows that slaughterhouses act as major enrichment nodes for tet(X4)‐mediated tigecycline resistance, driven by putative clonal transmission and stable plasmid backbones. Integrating global datasets enables lineage‐specific risk stratification, highlighting key control points ...
Qin Wang, Qiwu Yuan, Xuan Chen, Yujing Zhong, Ke Wu, Renqiao Wen, Luya Liu, Xiaoqin Wang, Cui Li, Hongning Wang, Changwei Lei   +10 more
wiley   +1 more source

Autoregulation of bacterial gene expression: lessons from the MazEF toxin-antitoxin system [PDF]

, 2019
Autoregulation is the direct modulation of gene expression by the product of the corresponding gene. Autoregulation of bacterial gene expression has been mostly studied at the transcriptional level, when a protein acts as the cognate transcriptional ...
Nikolic, Nela, Nikolic, Nela ; https://orcid.org/   +1 more
core   +1 more source

Genome‐Wide In Silico Analysis of the Type VI Secretion System (T6SS) Within the Morganella Genus

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
▪ Species‐specific T6SS patterns among Morganella genus (M. morganii and M. sibonii). ▪ Only one‐third of M. morganii isolates haboured a T6SS. ▪ All M. sibonii possess four T6SS clusters. ▪ M. sibonii exhibited a wide diversity of effectors compared to M. morganii.
Mathilde Duque, Aymeric Jacquemin, Delphine Girlich, Rémy A. Bonnin, Laurent Dortet   +4 more
wiley   +1 more source

Toxin-antitoxin system [PDF]

, 2018
Bakterije su razvile iznimnu sposobnost prilagodbe na različite životne uvjete. Uz pomoć raznih sustava i mehanizama daju brz stanični odgovor na stresore, tretman antibiotikom, stanje gladi i ostale nepovoljne uvjete. Jedan takav sustav pronađen je u
Matković, Katarina
core