Identification of type II toxin-antitoxin modules in Burkholderia pseudomallei [PDF]
© 2012 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reservedThis is an open access article that is freely available in ORE or from the publisher's web site. Please cite the published version.Type II
Butt, Aaron Trevor +3 more
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ABSTRACT Background and Aims Cirrhosis favours infections that can lead to liver decompensation and death. Some of these infections can be prevented by vaccination. This study aimed to evaluate the immune response after HBV, pneumococcal, diphtheria, and tetanus vaccination in cirrhotic patients.
Vincent Haghnejad +10 more
wiley +1 more source
A competence-regulated toxin-antitoxin system in Haemophilus influenzae.
Natural competence allows bacteria to respond to environmental and nutritional cues by taking up free DNA from their surroundings, thus gaining both nutrients and genetic information.
Hailey Findlay Black +6 more
doaj +1 more source
Identification of a VapBC toxin–antitoxin system in a thermophilic bacterium Thermus thermophilus HB27 [PDF]
There are 12 putative toxin–antitoxin (TA) loci in the Thermus thermophilus HB27 genome, including four VapBC and three HicBA families. Expression of these seven putative toxin genes in Escherichia coli demonstrated that one putative VapC toxin TTC0125 ...
Fan Yuqi +4 more
core +2 more sources
Viable but Nonculturable State, a Survival Strategy for Salmonella in Aquatic Environments
Transition of Salmonella from a culturable state to a viable but nonculturable state under various environmental stresses and current methods for detecting viable Salmonella in environmental samples. ABSTRACT In the relentless battle for survival, Salmonella has evolved mechanisms to withstand harsh conditions such as extreme temperatures, fluctuating ...
Sanelisiwe Thinasonke Duze +3 more
wiley +1 more source
parD toxin–antitoxin system of plasmid R1 – basic contributions, biotechnological applications and relationships with closely‐related toxin–antitoxin systems [PDF]
Toxin–antitoxin systems, as found in bacterial plasmids and their host chromosomes, play a role in the maintenance of genetic information, as well as in the response to stress. We describe the basic biology of the parD/kiskid toxin–antitoxin system of Escherichia coli plasmid R1, with an emphasis on regulation, toxin activity, potential applications in
Diago-Navarro, E. +7 more
openaire +4 more sources
Recent advances in noncanonical inhibition mechanisms of anti‐CRISPR proteins
Abstract The CRISPR‐Cas system constitutes an adaptive immune mechanism in prokaryotes that defends against mobile genetic elements. Within the perpetual co‐evolutionary arms race between bacteria and their viral predators, bacteriophages encode anti‐CRISPR (Acr) proteins that use sophisticated molecular strategies to sabotage CRISPR‐Cas function ...
Lingguang Yang +5 more
wiley +1 more source
Molecular bases and role of viruses in the human microbiome. [PDF]
Viruses are dependent biological entities that interact with the genetic material of most cells on the planet, including the trillions within the human microbiome.
Abeles, Shira R, Pride, David T
core +1 more source
ABSTRACT The extensive and indiscriminate use of antibiotics, which are intended to halt bacterial growth or eliminate them, has unintentionally given rise to antimicrobial resistance (AMR), which is a critical threat to global health. In the pursuit of alternative solutions, researchers have focused on type II toxin–antitoxin systems prevalent within ...
Hana Hasegawa +6 more
wiley +1 more source
Bistability in type I toxin-antitoxin systems may lead to stress-induced persister formation
Antibiotic persistence, characterized by a dormant subpopulation of bacterial cells that causes chronic and recurrent infections, remains poorly understood despite being recognized nearly a century ago. Toxin–antitoxin (TA) systems, which include a toxin
Sofija Markovic +3 more
doaj +1 more source

