Results 141 to 150 of about 17,352,598 (197)

Novel type II toxin-antitoxin systems with VapD-like proteins

mBio
Type II toxin-antitoxin (TA) systems are widespread in prokaryotes. They consist of neighboring genes encoding two small proteins: a toxin that inhibits a critical cellular process and an antitoxin that binds to and neutralizes the toxin.
Konstantin Gilep, Dmitry Bikmetov, Aleksandr Popov, Anastasiia Rusanova, Shunsuke Tagami, Svetlana Dubiley, Konstantin Severinov   +6 more
doaj   +1 more source

Bacterial toxin-antitoxin gene system as containment control in yeast cells

, 2000
The potential of a bacterial toxin-antitoxin gene system for use in containment control in eukaryotes was explored. The Escherichia coli relE and relB genes were expressed in the yeast Saccharomyces cerevisiae, Expression of the relE gene was highly ...
Gerdes, K., Piskur, Jure, Kristoffersen, P., Jensen, G. B.   +3 more
core   +1 more source

Toxin-antitoxin Systems: Classification, Biological Function and Application in Biotechnology

, 2014
The toxin-antitoxin (TA) systems are systems in which an unstable antitoxin inhibits a stable toxin. This review aims to introduce the TA system and its biological application in bacteria.
Raftari, M., Sekawi, Z., Sadeghifard, N., Ghafourian, S.   +3 more
core   +1 more source

Structural and functional characterization of VapBC52 toxin-antitoxin system from Mycobacterium tuberculosis. [PDF]

Nucleic Acids Res
Singh M, Singh C, Nair AV, Ahmad I, Sharma A, Bhasin M, Jain V, Singh R, Thakur KG.   +8 more
europepmc   +1 more source

Kinetic simulations of selected toxin-antitoxin modules

Moduli toksin-antitoksin so manjši genetski sistemi, ki so množično prisotni v genomih bakterij in arhej. Najpogosteje zaporedje vsebuje zapis za proteina toksin in antitoksin, ter operatorsko regijo, preko katere se uravnava nivo izražanja obeh ...
Urbič, Zala
core  

The toxin from the PemIK-Sa1 toxin-antitoxin system decreases <i>Staphylococcus aureus</i> resistance to antibiotics. [PDF]

Front Microbiol
Bonar E, Chlebicka K, Bukowski M, Jodłowska W, Kosecka-Strojek M, Rabięcny A, Suder P, Hopciaś M, Głowacka-Grzyb Z, Akkerboom V, Voss A, Sabat AJ, Władyka B.   +12 more
europepmc   +1 more source

Ribosomal RNA cleavage by the previously unidentified RelS-RelI toxin-antitoxin system controls growth of Mycobacterium tuberculosis. [PDF]

Nucleic Acids Res
Han X, Arrowsmith TJ, Karamycheva S, Xu X, Coddeville M, Pagès C, Voisin B, Gutierrez C, Neyrolles O, Makarova KS, Blower TR, Genevaux P.   +11 more
europepmc   +1 more source

A haloarchaeal VapBC toxin-antitoxin system: regulatory mechanism and role in establishing population heterogeneity to facilitate survival of subpopulations under stress conditions. [PDF]

Appl Environ Microbiol
He D, Lin Y, Zhang Y, Liu Y, Li P, Su X, Qu X, Liu Y, Shao X, Wen H, Luo H, Wu Y, Gan F, Tang X-F, Tang B.   +14 more
europepmc   +1 more source

A toxin/antitoxin system targeting the replication sliding-clamp induces competence in Streptococcus pneumoniae. [PDF]

PLoS Genet
Maziero M, Juillot D, Mortier-Barrière I, Carballido-Lopez R, Campo N, Genevaux P, Bordes P, Polard P, Bergé M.   +8 more
europepmc   +1 more source

Comparative in silico analysis of vapBC3 toxin-antitoxin system in Mycobacterium Bovis and Mycobacterium tuberculosis. [PDF]

Sci Rep
Shafipour M, Mohammadzadeh A, Tabrizi GF, Mahmoodi P, Ghaemi EA.   +4 more
europepmc   +1 more source