Cassette recombination dynamics within chromosomal integrons are regulated by toxin-antitoxin systems. [PDF]
Richard E +16 more
europepmc +1 more source
The Chlamydia-related Waddlia chondrophila encodes functional type II toxin-antitoxin systems. [PDF]
Ardissone S, Greub G.
europepmc +1 more source
Toxin/antitoxin systems induce persistence and work in concert with restriction/modification systems to inhibit phage. [PDF]
Fernández-García L +6 more
europepmc +1 more source
Type II and IV toxin-antitoxin systems coordinately stabilize the integrative and conjugative element of the ICESa2603 family conferring multiple drug resistance in Streptococcus suis. [PDF]
Gu Q +6 more
europepmc +1 more source
Unraveling the evolutionary dynamics of toxin-antitoxin systems in diverse genetic lineages of <i>Escherichia coli</i> including the high-risk clonal complexes. [PDF]
Singh A +4 more
europepmc +1 more source
Biology and evolution of bacterial toxin–antitoxin systems [PDF]
Toxin–antitoxin systems are widespread in bacterial genomes. They are usually composed of two elements: a toxin that inhibits an essential cellular process and an antitoxin that counteracts its cognate toxin.
Dukas Jurenas +2 more
exaly +4 more sources
Regulation of toxin–antitoxin systems by proteolysis
Toxin-antitoxin systems are widely distributed among many bacterial species, including human pathogens. Regulation of type II TA system functions, where both components are proteins, relies on proteolysis.
Urszula Zielenkiewicz
exaly +5 more sources
Toxin-antitoxin (TA) systems are small genetic elements composed of a toxin gene and its cognate antitoxin. The toxins of all known TA systems are proteins while the antitoxins are either proteins or non-coding RNAs. Based on the molecular nature of the antitoxin and its mode of interaction with the toxin the TA modules are currently grouped into five ...
Simon J Unterholzner +2 more
exaly +3 more sources
Toxin–antitoxin systems, as found in bacterial plasmids and their host chromosomes, play a role in the maintenance of genetic information, as well as in the response to stress.
Elizabeth Diago-Navarro +2 more
exaly +2 more sources

