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Toxin–antitoxin systems: why so many, what for?

Current Opinion in Microbiology, 2010
Toxin-antitoxin (TA) systems are small genetic modules that are abundant in bacterial genomes. Three types have been described so far, depending on the nature and mode of action of the antitoxin component. While type II systems are surprisingly highly represented because of their capacity to move by horizontal gene transfer, type I systems appear to ...
openaire   +3 more sources

[Functions of bacterial Toxin-Antitoxin systems].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2019
TA (Toxin-Antitoxin) systems are widely spread in chromosomes and plasmids of bacteria and archaea. These systems consist of two co-expression genes, encoding stable toxin and sensitive antitoxin, respectively. The toxicity of toxins usually inhibits bacterial growth and antitoxins can neutralize the toxins.
Zhili, He, Hui, Wang
openaire   +1 more source

Prokaryotic toxin–antitoxin systems: novel regulations of the toxins

Current Genetics, 2016
Toxin-antitoxin (TA) systems are widely conserved in prokaryotic plasmids and chromosomes and are linked to many roles in cell physiology, including plasmid maintenance, stress response, persistence and protection from phage infection. A TA system is composed of a stable toxin and a labile antitoxin that inhibits a harmful effect of the cognate toxin ...
openaire   +2 more sources

Toxin-Antitoxin Systems as Phage Defense Elements

Annual Review of Microbiology, 2022
Michele Leroux, Michael T Laub
exaly  

Regulation of growth and death in Escherichia coli by toxin–antitoxin systems

Nature Reviews Microbiology, 2011
Yoshihiro Yamaguchi   +2 more
exaly  

sRNAs in bacterial type I and type III toxin-antitoxin systems

FEMS Microbiology Reviews, 2015
Sabine Brantl, Brantl Sabine
exaly  

Toxin-antitoxin systems mqsR/ygiT and dinJ/relE of Xylella fastidiosa

Physiological and Molecular Plant Pathology, 2014
Elizabeth E Rogers, Drake C Stenger
exaly  

Within-host competition selects for plasmid-encoded toxin–antitoxin systems

Proceedings of the Royal Society B: Biological Sciences, 2010
Tim F Cooper   +2 more
exaly  

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