Results 1 to 10 of about 125,050 (146)

BIOLOGICAL ACTIVITY OF YERSINIA PSEUDOTUBERCULOSIS TOXINS

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. Study of effect of heat-labile (HLT) and thermostable (HST) lethal toxins of Yersinia pseudotuberculosis on the development of embryos of sea urchin Strongylocentrotus intermedius, processes of biosynthesis of nucleic acids and protein in embryo ...
N. A. Terentieva, N. F. Timchenko, V. A. Golotin, V. A. Rasskazov   +3 more
doaj   +4 more sources

Differentiation, Quantification and Identification of Abrin and Abrus precatorius Agglutinin

Toxins, 2021
Abrin, the toxic lectin from the rosary pea plant Abrus precatorius, has gained considerable interest in the recent past due to its potential malevolent use.
Sylvia Worbs, Bettina Kampa, Martin Skiba, Eva-Maria Hansbauer, Daniel Stern, Hervé Volland, François Becher, Stéphanie Simon, Martin B. Dorner, Brigitte G. Dorner   +9 more
doaj   +1 more source

A bead-based multiplex assay covering all coronaviruses pathogenic for humans for sensitive and specific surveillance of SARS-CoV-2 humoral immunity

Scientific Reports, 2023
Serological assays measuring antibodies against SARS-CoV-2 are key to describe the epidemiology, pathobiology or induction of immunity after infection or vaccination.
Daniel Stern, Tanja C. Meyer, Fridolin Treindl, Hans Werner Mages, Maren Krüger, Martin Skiba, Jan Philipp Krüger, Christian M. Zobel, Maximilian Schreiner, Marica Grossegesse, Thomas Rinner, Caroline Peine, Anna Stoliaroff-Pépin, Thomas Harder, Natalie Hofmann, Janine Michel, Andreas Nitsche, Silke Stahlberg, Antje Kneuer, Anna Sandoni, Ulrike Kubisch, Martin Schlaud, Annette Mankertz, Tatjana Schwarz, Victor M. Corman, Marcel A. Müller, Christian Drosten, Kathrin de la Rosa, Lars Schaade, Martin B. Dorner, Brigitte G. Dorner   +30 more
doaj   +1 more source

Innovative and Highly Sensitive Detection of Clostridium perfringens Enterotoxin Based on Receptor Interaction and Monoclonal Antibodies

Toxins, 2021
Clostridium perfringens enterotoxin (CPE) regularly causes food poisoning and antibiotic-associated diarrhea; therefore, reliable toxin detection is crucial.
Thea Neumann, Maren Krüger, Jasmin Weisemann, Stefan Mahrhold, Daniel Stern, Martin B. Dorner, Cécile Feraudet-Tarisse, Christopher Pöhlmann, Katharina Schulz, Ute Messelhäußer, Dagmar Rimek, Frank Gessler, Thomas Elßner, Stéphanie Simon, Andreas Rummel, Brigitte G. Dorner   +15 more
doaj   +1 more source

Construction and validation of safe Clostridium botulinum Group II surrogate strain producing inactive botulinum neurotoxin type E toxoid

Scientific Reports, 2022
Botulinum neurotoxins (BoNTs), produced by the spore-forming bacterium Clostridium botulinum, cause botulism, a rare but fatal illness affecting humans and animals.
Maria B. Nowakowska, Katja Selby, Adina Przykopanski, Maren Krüger, Nadja Krez, Brigitte G. Dorner, Martin B. Dorner, Rongsheng Jin, Nigel P. Minton, Andreas Rummel, Miia Lindström   +10 more
doaj   +1 more source

Development and Evaluation of an Immuno-MALDI-TOF Mass Spectrometry Approach for Quantification of the Abrin Toxin in Complex Food Matrices

Toxins, 2021
The toxin abrin found in the seeds of Abrus precatorius has attracted much attention regarding criminal and terroristic misuse over the past decade. Progress in analytical methods for a rapid and unambiguous identification of low abrin concentrations in ...
Sandrine Livet, Sylvia Worbs, Hervé Volland, Stéphanie Simon, Martin B. Dorner, François Fenaille, Brigitte G. Dorner, François Becher   +7 more
doaj   +1 more source

Optimization of SNAP-25 and VAMP-2 Cleavage by Botulinum Neurotoxin Serotypes A–F Employing Taguchi Design-of-Experiments

Toxins, 2019
The detection of catalytically active botulinum neurotoxins (BoNTs) can be achieved by monitoring the enzymatic cleavage of soluble NSF (N-ethylmaleimide-sensitive-factor) attachment protein receptor (SNARE) proteins by the toxins’ light chains (LC)
Laura von Berg, Daniel Stern, Jasmin Weisemann, Andreas Rummel, Martin Bernhard Dorner, Brigitte Gertrud Dorner   +5 more
doaj   +1 more source

An International Proficiency Test to Detect, Identify and Quantify Ricin in Complex Matrices

Toxins, 2015
While natural intoxications with seeds of Ricinus communis (R. communis) have long been known, the toxic protein ricin contained in the seeds is of major concern since it attracts attention of those intending criminal, terroristic and military misuse. In
Sylvia Worbs, Martin Skiba, Jennifer Bender, Reinhard Zeleny, Heinz Schimmel, Werner Luginbühl, Brigitte G. Dorner   +6 more
doaj   +1 more source

Multiplex Immunoassay Techniques for On-Site Detection of Security Sensitive Toxins

Toxins, 2020
Biological toxins are a heterogeneous group of high molecular as well as low molecular weight toxins produced by living organisms. Due to their physical and logistical properties, biological toxins are very attractive to terrorists for use in acts of ...
Christopher Pöhlmann, Thomas Elßner
doaj   +1 more source

Anti-trichomonad activities of different compounds from foods, marine products, and medicinal plants: a review

BMC Complementary Medicine and Therapies, 2020
Human trichomoniasis, caused by the pathogenic parasitic protozoan Trichomonas vaginalis, is the most common non-viral sexually transmitted disease that contributes to reproductive morbidity in affected women and possibly to prostate cancer in men ...
Mendel Friedman, Christina C. Tam, Luisa W. Cheng, Kirkwood M. Land   +3 more
doaj   +1 more source