Results 31 to 40 of about 2,559,591 (306)

Antibodies and Vaccines Against Botulinum Toxins: Available Measures and Novel Approaches

, 2019
International audienceBotulinum neurotoxin (BoNT) is produced by the anaerobic, Gram-positive bacterium Clostridium botulinum. As one of the most poisonous toxins known and a potential bioterrosism agent, BoNT is characterized by a complex mode of action
Rasetti-Escargueil, Christine, Michel R. Popoff, Popoff, Michel, Christine Rasetti-Escargueil   +3 more
core   +1 more source

Period1 mediates rhythmic metabolism of toxins by interacting with CYP2E1

Cell Death and Disease, 2021
The biological clock is an endogenous biological timing system, which controls metabolic functions in almost all organs. Nutrient metabolism, substrate processing, and detoxification are circadian controlled in livers.
Wenhao Ge, Tao Wang, Yang Zhao, Yunxia Yang, Qi Sun, Xiao Yang, Yan Gao, Xi Xu, Jianfa Zhang   +8 more
doaj   +1 more source

Biological Evaluation of Binding of Toxins to Microplastics [PDF]

Agrifoodplast : international conference on micro and nano-plastics in the agri-food chain (Agrifoodplast 2025), Abstracts, 8-9 April, 2025, Brussels, Belgium
Micro- and nanoplastics (MNPs) contaminate ecosystems worldwide and enter our food and water via the aquatic environment or plastic food containers. MNPs could serve as carriers of aquatic or food pathogens and/or their toxins, facilitated by their large surface area and hydrophobic nature.
Alderweireldt, Elien, Grootaert, Charlotte, Jacobs, Bram, Wimmer, Lukas, Dailey, Lea Ann, Cirkovic Velickovic, Tanja, Rajkovic, Andreja   +6 more
openaire   +3 more sources

Highly Sensitive Suspension Immunoassay for Multiplex Detection, Differentiation, and Quantification of Eight Staphylococcus aureus Enterotoxins (SEA to SEI)

Toxins
Staphylococcal enterotoxins (SEs) are major contributors to foodborne intoxications. Reliable detection methods for SEs are essential to maintain food safety and protect public health.
Paulin Dettmann, Martin Skiba, Daniel Stern, Jasmin Weisemann, Hans Werner Mages, Nadja Krez, Martin B. Dorner, Sara Schaarschmidt, Marc A. Avondet, Marcus Fulde, Andreas Rummel, Birgit Strommenger, Sven Maurischat, Brigitte G. Dorner   +13 more
doaj   +1 more source

Proteomic Methods of Detection and Quantification of Protein Toxins

Toxins, 2018
Biological toxins are a heterogeneous group of compounds that share commonalities with biological and chemical agents. Among them, protein toxins represent a considerable, diverse set.
Miloslava Duracova, Jana Klimentova, Alena Fucikova, Jiri Dresler   +3 more
doaj   +1 more source

Conflicting Clinical Presentation of Infection with Clostridium botulinum and Clostridium perfringens in a 5-Month-Old Infant

Journal of Pediatrics: Clinical Practice
We present a 5-month-old infant with a 1-day history of poor feeding and sudden progression into generalized weakness including septic shock syndrome after consumption of homemade food. Botulism and sepsis symptoms could be explained by the presence of a
Barbara Schaub, MD, Carolyn Luhman-Lunt, MD, Andrea Ott, MD, Maren Krüger, DSc, Martin Skiba, PhD, Sylvia Worbs, PhD, Brigitte G. Dorner, PhD, Michael Buettcher, MD, Martin B. Dorner, PhD   +8 more
doaj   +1 more source

Recommended Immunological Strategies to Screen for Botulinum Neurotoxin-Containing Samples

Toxins, 2015
Botulinum neurotoxins (BoNTs) cause the life-threatening neurological illness botulism in humans and animals and are divided into seven serotypes (BoNT/A–G), of which serotypes A, B, E, and F cause the disease in humans. BoNTs are classified as “category
Stéphanie Simon, Uwe Fiebig, Yvonne Liu, Rob Tierney, Julie Dano, Sylvia Worbs, Tanja Endermann, Marie-Claire Nevers, Hervé Volland, Dorothea Sesardic, Martin B. Dorner   +10 more
doaj   +1 more source

Bacterial Toxins, Current Perspectives

, 2020
Toxins are the major pathogenicity factors produced by numerous bacteria involved in severe diseases in humans and animals. Certain pathogenic bacteria synthesize only one toxin which is responsible for all the symptoms and outcome of the disease.
Michel R. Popoff
core   +1 more source

N-Glycosylation Profile of Abrin Certified EU Reference Material

Toxins
Abrin is a highly toxic plant protein encompassing four isoforms, abrin-a, -b, -c and -d. An abrin reference material was isolated from Abrus precatorius and certified (EURM-113) by the EuroBioTox consortium.
Roland Josuran, Andreas Wenger, Sylvia Worbs, Bettina Kampa, Andreas Rummel, Brigitte G. Dorner, Sabina Gerber   +6 more
doaj   +1 more source

Generation and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test

Toxins, 2015
The detection and identification of botulinum neurotoxins (BoNT) is complex due to the existence of seven serotypes, derived mosaic toxins and more than 40 subtypes. Expert laboratories currently use different technical approaches to detect, identify and
Jasmin Weisemann, Nadja Krez, Uwe Fiebig, Sylvia Worbs, Martin Skiba, Tanja Endermann, Martin B. Dorner, Tomas Bergström, Amalia Muñoz, Ingrid Zegers, Christian Müller, Stephen P. Jenkinson, Marc-Andre Avondet, Laurence Delbrassinne, Sarah Denayer, Reinhard Zeleny, Heinz Schimmel, Crister Åstot, Brigitte G. Dorner, Andreas Rummel   +19 more
doaj   +1 more source