Results 31 to 40 of about 3,656,607 (353)

Function Prediction of Peptide Toxins with Sequence-Based Multi-Tasking PU Learning Method

Toxins, 2022
Peptide toxins generally have extreme pharmacological activities and provide a rich source for the discovery of drug leads. However, determining the optimal activity of a new peptide can be a long and expensive process. In this study, peptide toxins were
Yanyan Chu, Huanhuan Zhang, Lei Zhang
doaj   +1 more source

Preamble [PDF]

, 2000
Ye
Pearson, Graham S., Sims, N.A.
core   +1 more source

Role of Uremic Toxins in Early Vascular Ageing and Calcification

Toxins, 2021
In patients with advanced chronic kidney disease (CKD), the accumulation of uremic toxins, caused by a combination of decreased excretion secondary to reduced kidney function and increased generation secondary to aberrant expression of metabolite genes ...
N. Kyriakidis, G. Cobo, L. Dai, B. Lindholm, P. Stenvinkel   +4 more
semanticscholar   +1 more source

Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin

Toxins, 2016
Botulinum neurotoxins (BoNTs) exhibit extraordinary potency due to their exquisite neurospecificity, which is achieved by dual binding to complex polysialo-gangliosides and synaptic vesicle proteins.
Jasmin Weisemann, Daniel Stern, Stefan Mahrhold, Brigitte G. Dorner, Andreas Rummel   +4 more
doaj   +1 more source

Biological Control of Mycotoxigenic Fungi and Their Toxins: An Update for the Pre-Harvest Approach

JSM Mycotoxins, 2018
Over recent decades, laboratory and field trial experiments have generated a considerable amount of data regarding the promising use of beneficial microorganisms to control plant diseases.
M. Abdallah, M. Ameye, S. Saeger, K. Audenaert, G. Haesaert   +4 more
semanticscholar   +1 more source

The Inhibitory Activity of Anthraquinones against Pathogenic Protozoa, Bacteria, and Fungi and the Relationship to Structure

Molecules, 2020
Plant-derived anthraquinones were evaluated in cell assays for their inhibitory activities against the parasitic protozoa Trichomonas vaginalis human strain G3 that causes the sexually transmitted disease trichomoniasis in women, Tritrichomonas foetus ...
Mendel Friedman, Alexander Xu, Rani Lee, Daniel N. Nguyen, Tina A. Phan, Sabrina M. Hamada, Rima Panchel, Christina C. Tam, Jong H. Kim, Luisa W. Cheng, Kirkwood M. Land   +10 more
doaj   +1 more source

Preclinical evaluation of a candidate naked plasmid DNA vaccine against SARS-CoV-2

npj Vaccines, 2021
New generation plasmid DNA vaccines may be a safe, fast and simple emergency vaccine platform for preparedness against emerging viral pathogens. Applying platform optimization strategies, we tested the pre-clinical immunogenicity and protective effect of
Ria Lassaunière, Charlotta Polacek, Gregers J. Gram, Anders Frische, Jeanette Linnea Tingstedt, Maren Krüger, Brigitte G. Dorner, Anthony Cook, Renita Brown, Tatyana Orekov, Tammy Putmon-Taylor, Tracey-Ann Campbell, Jack Greenhouse, Laurent Pessaint, Hanne Andersen, Mark G. Lewis, Anders Fomsgaard   +16 more
doaj   +1 more source

Paralytic shellfish toxins and ocean warming: bioaccumulation and ecotoxicological responses in jujvenile Gilthead Seabream (Sparus aurata) [PDF]

, 2019
Warmer seawater temperatures are expected to increase harmful algal blooms (HABs) occurrence, intensity, and distribution. Yet, the potential interactions between abiotic stressors and HABs are still poorly understood from ecological and seafood safety ...
Anacleto, Patrícia, Barbosa, Vera, Marques, António, Maulvault, Ana Luísa, Pousão-Ferreira, Pedro, Reis Costa, Pedro, Santos, Marta   +6 more
core   +1 more source

Expression of in vivo biotinylated recombinant antigens SAG1 and SAG2A from Toxoplasma gondii for improved seroepidemiological bead-based multiplex assays

BMC Biotechnology, 2020
Background Few bead-based multiplex assays have been described that detect antibodies against the protozoan parasite Toxoplasma gondii in large-scale seroepidemiological surveys. Moreover, each multiplex assay has specific variations or limitations, such
Sandra Klein, Daniel Stern, Frank Seeber
doaj   +1 more source

Gold nanomaterials for the selective capturing and SERS diagnosis of toxins in aqueous and biological fluids.

Biosensors & bioelectronics, 2017
A highly sensitive nanosensing method for the combined selective capture and SERS detection of Microcystin-LR (MC-LR) in blood plasma has been developed.
Waleed A Hassanain, E. Izake, M. Schmidt, G. Ayoko   +3 more
semanticscholar   +1 more source