Results 21 to 30 of about 129,432 (263)

The Inhibitory Activity of Anthraquinones against Pathogenic Protozoa, Bacteria, and Fungi and the Relationship to Structure

Molecules, 2020
Plant-derived anthraquinones were evaluated in cell assays for their inhibitory activities against the parasitic protozoa Trichomonas vaginalis human strain G3 that causes the sexually transmitted disease trichomoniasis in women, Tritrichomonas foetus ...
Mendel Friedman, Alexander Xu, Rani Lee, Daniel N. Nguyen, Tina A. Phan, Sabrina M. Hamada, Rima Panchel, Christina C. Tam, Jong H. Kim, Luisa W. Cheng, Kirkwood M. Land   +10 more
doaj   +1 more source

Expression of in vivo biotinylated recombinant antigens SAG1 and SAG2A from Toxoplasma gondii for improved seroepidemiological bead-based multiplex assays

BMC Biotechnology, 2020
Background Few bead-based multiplex assays have been described that detect antibodies against the protozoan parasite Toxoplasma gondii in large-scale seroepidemiological surveys. Moreover, each multiplex assay has specific variations or limitations, such
Sandra Klein, Daniel Stern, Frank Seeber
doaj   +1 more source

Friends or Foes? Emerging Impacts of Biological Toxins [PDF]

Trends in Biochemical Sciences, 2019
Toxins are substances produced from biological sources (e.g., animal, plants, microorganisms) that have deleterious effects on a living organism. Despite the obvious health concerns of being exposed to toxins, they are having substantial positive impacts in a number of industrial sectors.
Clark, Graeme C., Casewell, Nicholas R., Elliott, Christopher T., Harvey, Alan L., Jamieson, Andrew G., Strong, Peter N., Turner, Andrew D.   +6 more
openaire   +6 more sources

Preclinical evaluation of a candidate naked plasmid DNA vaccine against SARS-CoV-2

npj Vaccines, 2021
New generation plasmid DNA vaccines may be a safe, fast and simple emergency vaccine platform for preparedness against emerging viral pathogens. Applying platform optimization strategies, we tested the pre-clinical immunogenicity and protective effect of
Ria Lassaunière, Charlotta Polacek, Gregers J. Gram, Anders Frische, Jeanette Linnea Tingstedt, Maren Krüger, Brigitte G. Dorner, Anthony Cook, Renita Brown, Tatyana Orekov, Tammy Putmon-Taylor, Tracey-Ann Campbell, Jack Greenhouse, Laurent Pessaint, Hanne Andersen, Mark G. Lewis, Anders Fomsgaard   +16 more
doaj   +1 more source

Biological Evaluation of Binding of Toxins to Microplastics [PDF]

Agrifoodplast : international conference on micro and nano-plastics in the agri-food chain (Agrifoodplast 2025), Abstracts, 8-9 April, 2025, Brussels, Belgium
Micro- and nanoplastics (MNPs) contaminate ecosystems worldwide and enter our food and water via the aquatic environment or plastic food containers. MNPs could serve as carriers of aquatic or food pathogens and/or their toxins, facilitated by their large surface area and hydrophobic nature.
Alderweireldt, Elien, Grootaert, Charlotte, Jacobs, Bram, Wimmer, Lukas, Dailey, Lea Ann, Cirkovic Velickovic, Tanja, Rajkovic, Andreja   +6 more
openaire   +3 more sources

Anti-Parasitic Activity of Cherry Tomato Peel Powders

Foods, 2021
Trichomoniasis in humans, caused by the protozoal parasite Trichomonas vaginalis, is the most common non-viral sexually transmitted disease, while Tritrichomonas foetus causes trichomonosis, an infection of the gastrointestinal tract and diarrhea in farm
Mendel Friedman, Christina C. Tam, Jong H. Kim, Sydney Escobar, Steven Gong, Max Liu, Xuan Yu Mao, Cindy Do, Irene Kuang, Kelvin Boateng, Janica Ha, Megan Tran, Srimanth Alluri, Tam Le, Ryan Leong, Luisa W. Cheng, Kirkwood M. Land   +16 more
doaj   +1 more source

Period1 mediates rhythmic metabolism of toxins by interacting with CYP2E1

Cell Death and Disease, 2021
The biological clock is an endogenous biological timing system, which controls metabolic functions in almost all organs. Nutrient metabolism, substrate processing, and detoxification are circadian controlled in livers.
Wenhao Ge, Tao Wang, Yang Zhao, Yunxia Yang, Qi Sun, Xiao Yang, Yan Gao, Xi Xu, Jianfa Zhang   +8 more
doaj   +1 more source

Highly Sensitive Suspension Immunoassay for Multiplex Detection, Differentiation, and Quantification of Eight Staphylococcus aureus Enterotoxins (SEA to SEI)

Toxins
Staphylococcal enterotoxins (SEs) are major contributors to foodborne intoxications. Reliable detection methods for SEs are essential to maintain food safety and protect public health.
Paulin Dettmann, Martin Skiba, Daniel Stern, Jasmin Weisemann, Hans Werner Mages, Nadja Krez, Martin B. Dorner, Sara Schaarschmidt, Marc A. Avondet, Marcus Fulde, Andreas Rummel, Birgit Strommenger, Sven Maurischat, Brigitte G. Dorner   +13 more
doaj   +1 more source

Proteomic Methods of Detection and Quantification of Protein Toxins

Toxins, 2018
Biological toxins are a heterogeneous group of compounds that share commonalities with biological and chemical agents. Among them, protein toxins represent a considerable, diverse set.
Miloslava Duracova, Jana Klimentova, Alena Fucikova, Jiri Dresler   +3 more
doaj   +1 more source

Conflicting Clinical Presentation of Infection with Clostridium botulinum and Clostridium perfringens in a 5-Month-Old Infant

Journal of Pediatrics: Clinical Practice
We present a 5-month-old infant with a 1-day history of poor feeding and sudden progression into generalized weakness including septic shock syndrome after consumption of homemade food. Botulism and sepsis symptoms could be explained by the presence of a
Barbara Schaub, MD, Carolyn Luhman-Lunt, MD, Andrea Ott, MD, Maren Krüger, DSc, Martin Skiba, PhD, Sylvia Worbs, PhD, Brigitte G. Dorner, PhD, Michael Buettcher, MD, Martin B. Dorner, PhD   +8 more
doaj   +1 more source