Results 21 to 30 of about 2,559,591 (306)

Profiling hymenopteran venom toxins: Protein families, structural landscape, biological activities, and pharmacological benefits

open access: yesToxicon: X, 2022
Hymenopterans are an untapped source of venom secretions. Their recent proteo-transcriptomic studies have revealed an extraordinary pool of toxins that participate in various biological processes, including pain, paralysis, allergic reactions, and ...
Juan Carlos Guido-Patiño   +1 more
doaj   +1 more source

Biological Toxins as the Potential Tools for Bioterrorism [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Biological toxins are a heterogeneous group produced by living organisms. One dictionary defines them as “Chemicals produced by living organisms that have toxic properties for another organism”. Toxins are very attractive to terrorists for use in acts of bioterrorism. The first reason is that many biological toxins can be obtained very easily.
Edyta Janik   +3 more
openaire   +2 more sources

Function Prediction of Peptide Toxins with Sequence-Based Multi-Tasking PU Learning Method

open access: yesToxins, 2022
Peptide toxins generally have extreme pharmacological activities and provide a rich source for the discovery of drug leads. However, determining the optimal activity of a new peptide can be a long and expensive process. In this study, peptide toxins were
Yanyan Chu, Huanhuan Zhang, Lei Zhang
doaj   +1 more source

Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin

open access: yesToxins, 2016
Botulinum neurotoxins (BoNTs) exhibit extraordinary potency due to their exquisite neurospecificity, which is achieved by dual binding to complex polysialo-gangliosides and synaptic vesicle proteins.
Jasmin Weisemann   +4 more
doaj   +1 more source

Biological Toxins [PDF]

open access: yes, 2018
With the financial support of Internal Security Fund Police Programme European Commission Directorate General Home Affairs. This project has been founded with support from the European Commission. This publication reflects the views only of the authors, and European Commission cannot be held responsible for any use which may be made of the information ...
openaire   +3 more sources

The Inhibitory Activity of Anthraquinones against Pathogenic Protozoa, Bacteria, and Fungi and the Relationship to Structure

open access: yesMolecules, 2020
Plant-derived anthraquinones were evaluated in cell assays for their inhibitory activities against the parasitic protozoa Trichomonas vaginalis human strain G3 that causes the sexually transmitted disease trichomoniasis in women, Tritrichomonas foetus ...
Mendel Friedman   +10 more
doaj   +1 more source

Preclinical evaluation of a candidate naked plasmid DNA vaccine against SARS-CoV-2

open access: yesnpj Vaccines, 2021
New generation plasmid DNA vaccines may be a safe, fast and simple emergency vaccine platform for preparedness against emerging viral pathogens. Applying platform optimization strategies, we tested the pre-clinical immunogenicity and protective effect of
Ria Lassaunière   +16 more
doaj   +1 more source

Expression of in vivo biotinylated recombinant antigens SAG1 and SAG2A from Toxoplasma gondii for improved seroepidemiological bead-based multiplex assays

open access: yesBMC Biotechnology, 2020
Background Few bead-based multiplex assays have been described that detect antibodies against the protozoan parasite Toxoplasma gondii in large-scale seroepidemiological surveys. Moreover, each multiplex assay has specific variations or limitations, such
Sandra Klein, Daniel Stern, Frank Seeber
doaj   +1 more source

Friends or Foes? Emerging Impacts of Biological Toxins [PDF]

open access: yesTrends in Biochemical Sciences, 2019
Toxins are substances produced from biological sources (e.g., animal, plants, microorganisms) that have deleterious effects on a living organism. Despite the obvious health concerns of being exposed to toxins, they are having substantial positive impacts in a number of industrial sectors.
Clark, Graeme C.   +6 more
openaire   +6 more sources

Anti-Parasitic Activity of Cherry Tomato Peel Powders

open access: yesFoods, 2021
Trichomoniasis in humans, caused by the protozoal parasite Trichomonas vaginalis, is the most common non-viral sexually transmitted disease, while Tritrichomonas foetus causes trichomonosis, an infection of the gastrointestinal tract and diarrhea in farm
Mendel Friedman   +16 more
doaj   +1 more source

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