Results 21 to 30 of about 3,656,607 (353)

Biological Activity of Heated Diphtheria Toxin [PDF]

Journal of Bacteriology, 1973
Diphtheria toxin splits into two fragments when heated at 100 C for 10 min in a phosphate buffer. The separated fragments have molecular weights of 24,000 and 39,000, respectively. These molecular weights are similar to those of the A and B fragments found in diphtheria toxin preparations after thiol reduction.
G, Cukor, M, Solotorovsky, R J, Kuchler
openaire   +2 more sources

Qualitative and Quantitative Detection of Botulinum Neurotoxins from Complex Matrices: Results of the First International Proficiency Test

Toxins, 2015
In the framework of the EU project EQuATox, a first international proficiency test (PT) on the detection and quantification of botulinum neurotoxins (BoNT) was conducted.
Sylvia Worbs, Uwe Fiebig, Reinhard Zeleny, Heinz Schimmel, Andreas Rummel, Werner Luginbühl, Brigitte G. Dorner   +6 more
doaj   +1 more source

Uremic Toxins and Their Relation with Oxidative Stress Induced in Patients with CKD

International Journal of Molecular Sciences, 2021
The presence of toxins is believed to be a major factor in the development of uremia in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD).
A. Pieniazek, Joanna Bernasińska-Słomczewska, Lukasz Gwozdzinski   +2 more
semanticscholar   +1 more source

Transcriptional cellular responses in midgut tissue of Aedes aegypti larvae following intoxication with Cry11Aa toxin from Bacillus thuringiensis. [PDF]

, 2015
BackgroundAlthough much is known about the mechanism of action of Bacillus thuringiensis Cry toxins, the target tissue cellular responses to toxin activity is less understood.
Bravo, Alejandra, Cancino-Rodezno, Angeles, Canton, Pablo Emiliano, Gill, Sarjeet S, Soberón, Mario   +4 more
core   +1 more source

Biomembrane-Modified Field Effect Transistors for Sensitive and Quantitative Detection of Biological Toxins and Pathogens.

ACS Nano, 2019
The efforts of detecting bioactive targets with complex, dynamic, and unknown molecular profiles have inspired the development of various biosensor platforms.
Hua Gong, Fang Chen, Zhenlong Huang, Yue Gu, Qiangzhe Zhang, Yijie Chen, Yue Zhang, Jia Zhuang, Yoon‐Kyoung Cho, Ronnie H. Fang, Weiwei Gao, Sheng Xu, Liangfang Zhang   +12 more
semanticscholar   +1 more source

Botulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q58–K59 Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities

Toxins, 2018
In the recent past, about 40 botulinum neurotoxin (BoNT) subtypes belonging to serotypes A, B, E, and F pathogenic to humans were identified among hundreds of independent isolates.
Stefan Sikorra, Martin Skiba, Martin B. Dorner, Jasmin Weisemann, Mirjam Weil, Sylvia Valdezate, Bazbek Davletov, Andreas Rummel, Brigitte G. Dorner, Thomas Binz   +9 more
doaj   +1 more source

Biological Toxins as the Potential Tools for Bioterrorism

International Journal of Molecular Sciences, 2019
Biological toxins are a heterogeneous group produced by living organisms. One dictionary defines them as “Chemicals produced by living organisms that have toxic properties for another organism”. Toxins are very attractive to terrorists for use in acts of
Edyta Janik, Michal Ceremuga, Joanna Saluk-Bijak, M. Bijak   +3 more
semanticscholar   +1 more source

Profiling hymenopteran venom toxins: Protein families, structural landscape, biological activities, and pharmacological benefits

Toxicon: X, 2022
Hymenopterans are an untapped source of venom secretions. Their recent proteo-transcriptomic studies have revealed an extraordinary pool of toxins that participate in various biological processes, including pain, paralysis, allergic reactions, and ...
Juan Carlos Guido-Patiño, Fabien Plisson   +1 more
doaj   +1 more source

Last decade update for three-finger toxins: Newly emerging structures and biological activities

World Journal of Biological Chemsitry, 2019
Three-finger toxins (TFTs) comprise one of largest families of snake venom toxins. While they are principal to and the most toxic components of the venoms of the Elapidae snake family, their presence has also been detected in the venoms of snakes from ...
Y. Utkin
semanticscholar   +1 more source

Preface Biological Toxins—Ancient Molecules Posing a Current Threat

Toxins, 2015
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Brigitte G. Dorner, Andreas Rummel
doaj   +1 more source