Results 21 to 30 of about 3,525,662 (309)

Uremic Toxins and Their Relation with Oxidative Stress Induced in Patients with CKD

International Journal of Molecular Sciences, 2021
The presence of toxins is believed to be a major factor in the development of uremia in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD).
A. Pieniazek, Joanna Bernasińska-Słomczewska, Lukasz Gwozdzinski   +2 more
semanticscholar   +1 more source

Biomembrane-Modified Field Effect Transistors for Sensitive and Quantitative Detection of Biological Toxins and Pathogens.

ACS Nano, 2019
The efforts of detecting bioactive targets with complex, dynamic, and unknown molecular profiles have inspired the development of various biosensor platforms.
Hua Gong, Fang Chen, Zhenlong Huang, Yue Gu, Qiangzhe Zhang, Yijie Chen, Yue Zhang, Jia Zhuang, Yoon‐Kyoung Cho, Ronnie H. Fang, Weiwei Gao, Sheng Xu, Liangfang Zhang   +12 more
semanticscholar   +1 more source

Botulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q58–K59 Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities

Toxins, 2018
In the recent past, about 40 botulinum neurotoxin (BoNT) subtypes belonging to serotypes A, B, E, and F pathogenic to humans were identified among hundreds of independent isolates.
Stefan Sikorra, Martin Skiba, Martin B. Dorner, Jasmin Weisemann, Mirjam Weil, Sylvia Valdezate, Bazbek Davletov, Andreas Rummel, Brigitte G. Dorner, Thomas Binz   +9 more
doaj   +1 more source

Profiling hymenopteran venom toxins: Protein families, structural landscape, biological activities, and pharmacological benefits

Toxicon: X, 2022
Hymenopterans are an untapped source of venom secretions. Their recent proteo-transcriptomic studies have revealed an extraordinary pool of toxins that participate in various biological processes, including pain, paralysis, allergic reactions, and ...
Juan Carlos Guido-Patiño, Fabien Plisson   +1 more
doaj   +1 more source

Last decade update for three-finger toxins: Newly emerging structures and biological activities

World Journal of Biological Chemsitry, 2019
Three-finger toxins (TFTs) comprise one of largest families of snake venom toxins. While they are principal to and the most toxic components of the venoms of the Elapidae snake family, their presence has also been detected in the venoms of snakes from ...
Y. Utkin
semanticscholar   +1 more source

Preface Biological Toxins—Ancient Molecules Posing a Current Threat

Toxins, 2015
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Brigitte G. Dorner, Andreas Rummel
doaj   +1 more source

Function Prediction of Peptide Toxins with Sequence-Based Multi-Tasking PU Learning Method

Toxins, 2022
Peptide toxins generally have extreme pharmacological activities and provide a rich source for the discovery of drug leads. However, determining the optimal activity of a new peptide can be a long and expensive process. In this study, peptide toxins were
Yanyan Chu, Huanhuan Zhang, Lei Zhang
doaj   +1 more source

Role of Uremic Toxins in Early Vascular Ageing and Calcification

Toxins, 2021
In patients with advanced chronic kidney disease (CKD), the accumulation of uremic toxins, caused by a combination of decreased excretion secondary to reduced kidney function and increased generation secondary to aberrant expression of metabolite genes ...
N. Kyriakidis, G. Cobo, L. Dai, B. Lindholm, P. Stenvinkel   +4 more
semanticscholar   +1 more source

Biological Control of Mycotoxigenic Fungi and Their Toxins: An Update for the Pre-Harvest Approach

JSM Mycotoxins, 2018
Over recent decades, laboratory and field trial experiments have generated a considerable amount of data regarding the promising use of beneficial microorganisms to control plant diseases.
M. Abdallah, M. Ameye, S. Saeger, K. Audenaert, G. Haesaert   +4 more
semanticscholar   +1 more source

Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin

Toxins, 2016
Botulinum neurotoxins (BoNTs) exhibit extraordinary potency due to their exquisite neurospecificity, which is achieved by dual binding to complex polysialo-gangliosides and synaptic vesicle proteins.
Jasmin Weisemann, Daniel Stern, Stefan Mahrhold, Brigitte G. Dorner, Andreas Rummel   +4 more
doaj   +1 more source