Results 21 to 30 of about 2,552,266 (246)

Biological Activity of Heated Diphtheria Toxin [PDF]

open access: yesJournal of Bacteriology, 1973
Diphtheria toxin splits into two fragments when heated at 100 C for 10 min in a phosphate buffer. The separated fragments have molecular weights of 24,000 and 39,000, respectively. These molecular weights are similar to those of the A and B fragments found in diphtheria toxin preparations after thiol reduction.
G, Cukor, M, Solotorovsky, R J, Kuchler
openaire   +2 more sources

Acknowledgment to Reviewers of Toxins in 2020

open access: yes, 2021
Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Toxins maintains its standards for the high quality of its published papers [...
Toxins Editorial Office Toxins Editorial Office   +2 more
core   +2 more sources

Botulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q58–K59 Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities

open access: yesToxins, 2018
In the recent past, about 40 botulinum neurotoxin (BoNT) subtypes belonging to serotypes A, B, E, and F pathogenic to humans were identified among hundreds of independent isolates.
Stefan Sikorra   +9 more
doaj   +1 more source

Preface Biological Toxins—Ancient Molecules Posing a Current Threat

open access: yesToxins, 2015
n ...
Brigitte G. Dorner, Andreas Rummel
doaj   +1 more source

Profiling hymenopteran venom toxins: Protein families, structural landscape, biological activities, and pharmacological benefits

open access: yesToxicon: X, 2022
Hymenopterans are an untapped source of venom secretions. Their recent proteo-transcriptomic studies have revealed an extraordinary pool of toxins that participate in various biological processes, including pain, paralysis, allergic reactions, and ...
Juan Carlos Guido-Patiño   +1 more
doaj   +1 more source

Function Prediction of Peptide Toxins with Sequence-Based Multi-Tasking PU Learning Method

open access: yesToxins, 2022
Peptide toxins generally have extreme pharmacological activities and provide a rich source for the discovery of drug leads. However, determining the optimal activity of a new peptide can be a long and expensive process. In this study, peptide toxins were
Yanyan Chu, Huanhuan Zhang, Lei Zhang
doaj   +1 more source

Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin

open access: yesToxins, 2016
Botulinum neurotoxins (BoNTs) exhibit extraordinary potency due to their exquisite neurospecificity, which is achieved by dual binding to complex polysialo-gangliosides and synaptic vesicle proteins.
Jasmin Weisemann   +4 more
doaj   +1 more source

Biological Toxins [PDF]

open access: yes, 2018
With the financial support of Internal Security Fund Police Programme European Commission Directorate General Home Affairs. This project has been founded with support from the European Commission. This publication reflects the views only of the authors, and European Commission cannot be held responsible for any use which may be made of the information ...
openaire   +3 more sources

Biological Toxins as the Potential Tools for Bioterrorism [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Biological toxins are a heterogeneous group produced by living organisms. One dictionary defines them as “Chemicals produced by living organisms that have toxic properties for another organism”. Toxins are very attractive to terrorists for use in acts of bioterrorism. The first reason is that many biological toxins can be obtained very easily.
Edyta Janik   +3 more
openaire   +2 more sources

The Inhibitory Activity of Anthraquinones against Pathogenic Protozoa, Bacteria, and Fungi and the Relationship to Structure

open access: yesMolecules, 2020
Plant-derived anthraquinones were evaluated in cell assays for their inhibitory activities against the parasitic protozoa Trichomonas vaginalis human strain G3 that causes the sexually transmitted disease trichomoniasis in women, Tritrichomonas foetus ...
Mendel Friedman   +10 more
doaj   +1 more source

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