Results 11 to 20 of about 2,552,266 (246)

Construction and validation of safe Clostridium botulinum Group II surrogate strain producing inactive botulinum neurotoxin type E toxoid

Scientific Reports, 2022
Botulinum neurotoxins (BoNTs), produced by the spore-forming bacterium Clostridium botulinum, cause botulism, a rare but fatal illness affecting humans and animals.
Maria B. Nowakowska, Katja Selby, Adina Przykopanski, Maren Krüger, Nadja Krez, Brigitte G. Dorner, Martin B. Dorner, Rongsheng Jin, Nigel P. Minton, Andreas Rummel, Miia Lindström   +10 more
doaj   +1 more source

Development and Evaluation of an Immuno-MALDI-TOF Mass Spectrometry Approach for Quantification of the Abrin Toxin in Complex Food Matrices

Toxins, 2021
The toxin abrin found in the seeds of Abrus precatorius has attracted much attention regarding criminal and terroristic misuse over the past decade. Progress in analytical methods for a rapid and unambiguous identification of low abrin concentrations in ...
Sandrine Livet, Sylvia Worbs, Hervé Volland, Stéphanie Simon, Martin B. Dorner, François Fenaille, Brigitte G. Dorner, François Becher   +7 more
doaj   +1 more source

The effect of Staphylococcus aureus carriage in late pregnancy on antibody levels to staphylococcal toxins in cord blood and breast milk. [PDF]

, 2008
We investigated the effect of carriage of Staphylococcus aureus in the later stages of pregnancy on levels of antibody specific to the S. aureus toxins, staphylococcal enterotoxin B (SEB), staphylococcal enterotoxin C (SEC) and toxic shock syndrome toxin-
Morris, James A., Telford, David R., Lauder, Robert M., Harrison, Linda M.   +3 more
core   +4 more sources

Role of Uremic Toxins in Early Vascular Ageing and Calcification

, 2021
In patients with advanced chronic kidney disease (CKD), the accumulation of uremic toxins, caused by a combination of decreased excretion secondary to reduced kidney function and increased generation secondary to aberrant expression of metabolite genes ...
Kyriakidis, NC, Peter Stenvinkel, Lu Dai, Gabriela Cobo, Stenvinkel, P,, Cobo, G, Dai, L,, Nikolaos C. Kyriakidis, Lindholm, B,, Bengt Lindholm   +9 more
core   +1 more source

Marine Toxins: Chemistry, Toxcity, Occurrence and Detection, with Special Reference to the Dutch Situation [PDF]

, 2010
Various species of algae can produce marine toxins under certain circumstances. These toxins can then accumulate in shellfish such as mussels, oysters and scallops. When these contaminated shellfish species are consumed severe intoxication can occur. The
de Boer, J.; id_orcid, Poelman, M., van den Top, H.J., Pol-Hofstad, I.E., Gerssen, A., Hofstad, I.E., Mulder, P.P.J., Boer, J., de, Pol-Hofstad, Mulder, Poelman, Top, H.J., van den, Gerssen, De Boer, Van den Top   +14 more
core   +1 more source

Optimization of SNAP-25 and VAMP-2 Cleavage by Botulinum Neurotoxin Serotypes A–F Employing Taguchi Design-of-Experiments

Toxins, 2019
The detection of catalytically active botulinum neurotoxins (BoNTs) can be achieved by monitoring the enzymatic cleavage of soluble NSF (N-ethylmaleimide-sensitive-factor) attachment protein receptor (SNARE) proteins by the toxins’ light chains (LC)
Laura von Berg, Daniel Stern, Jasmin Weisemann, Andreas Rummel, Martin Bernhard Dorner, Brigitte Gertrud Dorner   +5 more
doaj   +1 more source

An International Proficiency Test to Detect, Identify and Quantify Ricin in Complex Matrices

Toxins, 2015
While natural intoxications with seeds of Ricinus communis (R. communis) have long been known, the toxic protein ricin contained in the seeds is of major concern since it attracts attention of those intending criminal, terroristic and military misuse. In
Sylvia Worbs, Martin Skiba, Jennifer Bender, Reinhard Zeleny, Heinz Schimmel, Werner Luginbühl, Brigitte G. Dorner   +6 more
doaj   +1 more source

Multiplex Immunoassay Techniques for On-Site Detection of Security Sensitive Toxins

Toxins, 2020
Biological toxins are a heterogeneous group of high molecular as well as low molecular weight toxins produced by living organisms. Due to their physical and logistical properties, biological toxins are very attractive to terrorists for use in acts of ...
Christopher Pöhlmann, Thomas Elßner
doaj   +1 more source

Anti-trichomonad activities of different compounds from foods, marine products, and medicinal plants: a review

BMC Complementary Medicine and Therapies, 2020
Human trichomoniasis, caused by the pathogenic parasitic protozoan Trichomonas vaginalis, is the most common non-viral sexually transmitted disease that contributes to reproductive morbidity in affected women and possibly to prostate cancer in men ...
Mendel Friedman, Christina C. Tam, Luisa W. Cheng, Kirkwood M. Land   +3 more
doaj   +1 more source

Qualitative and Quantitative Detection of Botulinum Neurotoxins from Complex Matrices: Results of the First International Proficiency Test

Toxins, 2015
In the framework of the EU project EQuATox, a first international proficiency test (PT) on the detection and quantification of botulinum neurotoxins (BoNT) was conducted.
Sylvia Worbs, Uwe Fiebig, Reinhard Zeleny, Heinz Schimmel, Andreas Rummel, Werner Luginbühl, Brigitte G. Dorner   +6 more
doaj   +1 more source