Results 11 to 20 of about 3,525,662 (309)

Construction and validation of safe Clostridium botulinum Group II surrogate strain producing inactive botulinum neurotoxin type E toxoid

open access: yesScientific Reports, 2022
Botulinum neurotoxins (BoNTs), produced by the spore-forming bacterium Clostridium botulinum, cause botulism, a rare but fatal illness affecting humans and animals.
Maria B. Nowakowska   +10 more
doaj   +1 more source

Development and Evaluation of an Immuno-MALDI-TOF Mass Spectrometry Approach for Quantification of the Abrin Toxin in Complex Food Matrices

open access: yesToxins, 2021
The toxin abrin found in the seeds of Abrus precatorius has attracted much attention regarding criminal and terroristic misuse over the past decade. Progress in analytical methods for a rapid and unambiguous identification of low abrin concentrations in ...
Sandrine Livet   +7 more
doaj   +1 more source

Immunoaffinity Extraction and Alternative Approaches for the Analysis of Toxins in Environmental, Food or Biological Matrices

open access: yesToxins, 2020
The evolution of instrumentation in terms of separation and detection allowed a real improvement of the sensitivity and analysis time. However, the analysis of ultra-traces of toxins in complex samples requires often a step of purification and even ...
N. Delaunay, A. Combès, V. Pichon
semanticscholar   +1 more source

Plant Toxic Proteins: Their Biological Activities, Mechanism of Action and Removal Strategies

open access: yesToxins, 2023
Plants evolve to synthesize various natural metabolites to protect themselves against threats, such as insects, predators, microorganisms, and environmental conditions (such as temperature, pH, humidity, salt, and drought).
E. Kocyigit   +4 more
semanticscholar   +1 more source

Optimization of SNAP-25 and VAMP-2 Cleavage by Botulinum Neurotoxin Serotypes A–F Employing Taguchi Design-of-Experiments

open access: yesToxins, 2019
The detection of catalytically active botulinum neurotoxins (BoNTs) can be achieved by monitoring the enzymatic cleavage of soluble NSF (N-ethylmaleimide-sensitive-factor) attachment protein receptor (SNARE) proteins by the toxins’ light chains (LC)
Laura von Berg   +5 more
doaj   +1 more source

An International Proficiency Test to Detect, Identify and Quantify Ricin in Complex Matrices

open access: yesToxins, 2015
While natural intoxications with seeds of Ricinus communis (R. communis) have long been known, the toxic protein ricin contained in the seeds is of major concern since it attracts attention of those intending criminal, terroristic and military misuse. In
Sylvia Worbs   +6 more
doaj   +1 more source

Multiplex Immunoassay Techniques for On-Site Detection of Security Sensitive Toxins

open access: yesToxins, 2020
Biological toxins are a heterogeneous group of high molecular as well as low molecular weight toxins produced by living organisms. Due to their physical and logistical properties, biological toxins are very attractive to terrorists for use in acts of ...
Christopher Pöhlmann, Thomas Elßner
doaj   +1 more source

Anti-trichomonad activities of different compounds from foods, marine products, and medicinal plants: a review

open access: yesBMC Complementary Medicine and Therapies, 2020
Human trichomoniasis, caused by the pathogenic parasitic protozoan Trichomonas vaginalis, is the most common non-viral sexually transmitted disease that contributes to reproductive morbidity in affected women and possibly to prostate cancer in men ...
Mendel Friedman   +3 more
doaj   +1 more source

Biological Activity of Heated Diphtheria Toxin [PDF]

open access: yesJournal of Bacteriology, 1973
Diphtheria toxin splits into two fragments when heated at 100 C for 10 min in a phosphate buffer. The separated fragments have molecular weights of 24,000 and 39,000, respectively. These molecular weights are similar to those of the A and B fragments found in diphtheria toxin preparations after thiol reduction.
G, Cukor, M, Solotorovsky, R J, Kuchler
openaire   +2 more sources

Qualitative and Quantitative Detection of Botulinum Neurotoxins from Complex Matrices: Results of the First International Proficiency Test

open access: yesToxins, 2015
In the framework of the EU project EQuATox, a first international proficiency test (PT) on the detection and quantification of botulinum neurotoxins (BoNT) was conducted.
Sylvia Worbs   +6 more
doaj   +1 more source

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