Results 51 to 60 of about 286,913 (269)

Structural and Functional Diversity of Animal Toxins Interacting With GPCRs

Frontiers in Molecular Biosciences, 2022
Peptide toxins from venoms have undergone a long evolutionary process allowing host defense or prey capture and making them highly selective and potent for their target.
Anne-Cécile Van Baelen, Philippe Robin, Pascal Kessler, Arhamatoulaye Maïga, Arhamatoulaye Maïga, Nicolas Gilles, Denis Servent   +6 more
doaj   +1 more source

Shiga Toxin Detection Methods : A Short Review [PDF]

, 2013
The Shiga toxins comprise a family of related protein toxins secreted by certain types of bacteria. Shigella dysenteriae, some strain of Escherichia coli and other bacterias can express toxins which caused serious complication during the infection. Shiga
González-Aguilar, G., Guerrero, Y. Castaño   +1 more
core  

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Effects of Clostridium perfringens iota toxin in the small intestine of mice [PDF]

, 2017
Iota toxin is a binary toxin solely produced by Clostridium perfringens type E strains, and is structurally related to CDT from C. difficile and CST from C. spiroforme.
Bruzzone, Octavio Augusto, Cangelosi, Adriana, Dailoff, Gabriela Cecilia, Díaz Carrasco, Juan María, Fernandez Miyakawa, Mariano Enrique, Geoghegan, Patricia, Leiva, Carlos Leónidas, Redondo, Enzo Alejandro, Redondo, Leandro Martin   +8 more
core   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

Hosts and Heterologous Expression Strategies of Recombinant Toxins for Therapeutic Purposes

Toxins, 2023
The production of therapeutic recombinant toxins requires careful host cell selection. Bacteria, yeast, and mammalian cells are common choices, but no universal solution exists.
Luana di Leandro, Martina Colasante, Giuseppina Pitari, Rodolfo Ippoliti   +3 more
doaj   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

Colubrid Venom Composition: An -Omics Perspective

Toxins, 2016
Snake venoms have been subjected to increasingly sensitive analyses for well over 100 years, but most research has been restricted to front-fanged snakes, which actually represent a relatively small proportion of extant species of advanced snakes ...
Inácio L. M. Junqueira-de-Azevedo, Pollyanna F. Campos, Ana T. C. Ching, Stephen P. Mackessy   +3 more
doaj   +1 more source

Design of microfluidic networks [PDF]

, 2005
Microfluidics is a relatively new and fast growing research area in fluid mechanics. The devices in question are thin wafers containing etched or printed interconnecting channels through which fluids are pumped, which can mix and/or react at various ...
Billingham, John, Grief, Andrew, Leppinen, David, Ovenden, Nick   +3 more
core