Innate, adaptive, and cell-autonomous immunity against Toxoplasma gondii infection
Hosts have been fighting pathogens throughout the evolution of all infectious diseases. Toxoplasma gondii is one of the most common infectious agents in humans but causes only opportunistic infection in healthy individuals.
Miwa Sasai, Masahiro Yamamoto
semanticscholar +1 more source
Background. Toxoplasmosis is a widespread cosmopolitan anthropozoonosis, which affects more than a third of the world population. Except the modes of transmission well known, Toxoplasma gondii can be transmitted during transplantation or blood ...
Liliane Siransy+7 more
doaj +1 more source
Biogenesis and secretion of micronemes in Toxoplasma gondii
One of the hallmarks of the parasitic phylum of Apicomplexa is the presence of highly specialised, apical secretory organelles, called the micronemes and rhoptries that play critical roles in ensuring survival and dissemination.
David J Dubois, Dominique Soldati-Favre
semanticscholar +1 more source
Prenatal Toxoplasma gondii [PDF]
(See the article by Boyer et al, on pages 1081–9.) One of the first lessons regarding congenital infections taught to third-year medical students on obstetrics and reinforced during their pediatric rotations are the variety and pathogenesis of perinatal viral and parasitic infections that can affect pregnant women and their fetuses. From the time of
openaire +3 more sources
Detection of Toxoplasma gondii Parasite on Blood Donor at PMI Kabupaten Magelang by Rapid Diagnostic Methods in 2022 [PDF]
Toxoplasma gondii is a parasite that can infect most warm-blooded animals, including humans. The infection is caused by Toxoplasma gondii called Toxoplasmosis. Toxoplasmosis transmission can occur because of human behaviour’s such as keeping cats, eating
Widyaswara Gravinda+4 more
doaj +1 more source
Nested PCR methods for detection Toxoplasma gondii B1 gene in Cerebrospinal Fluid of HIV patients
Background: Toxoplasmosis is a disease caused by infection of Toxoplasma gondii, Which may cause a life-threatening condition in immunocompromised patients, for example, Toxoplasma encephalitis (TE). It is challenging to diagnose Toxoplasma as a cause of
Ryan Halleyantoro+3 more
doaj +1 more source
Toxoplasma gondii infection and toxoplasmosis in North Africa: a review
Toxoplasmosis is an important zoonosis caused by an obligate intracellular parasitic protozoan, Toxoplasma gondii. The disease is distributed worldwide and can affect all warm-blooded vertebrates, including humans.
M. Rouatbi+11 more
semanticscholar +1 more source
QuilA-adjuvanted T. gondii lysate antigens trigger robust antibody and IFNγ+ T cell responses in pigs leading to reduction in parasite DNA in tissues upon challenge infection [PDF]
Toxoplasma gondii is an intracellular parasite of all mammals and birds, responsible for toxoplasmosis. In healthy individuals T. gondii infections mostly remain asymptomatic, however this parasite causes severe morbidity and mortality in ...
Cox, Eric+6 more
core +2 more sources
High levels of congenital transmission of toxoplasma gondii in longitudinal and cross-sectional studies on sheep farms provides evidence of vertical transmission in ovine hosts [PDF]
Recent research suggests that vertical transmission may play an important role in sustaining Toxoplasma gondii infection in some species. We report here that congenital transmission occurs at consistently high levels in pedigree Charollais and outbred ...
Duncanson, P+6 more
core +1 more source
The Secreted Acid Phosphatase Domain-Containing GRA44 from Toxoplasma gondii Is Required for c-Myc Induction in Infected Cells. [PDF]
During host cell invasion, the eukaryotic pathogen Toxoplasma gondii forms a parasitophorous vacuole to safely reside within the cell, while it is partitioned from host cell defense mechanisms.
Arrizabalaga, Gustavo+2 more
core +1 more source