Results 91 to 100 of about 179,934 (163)

TP53 minigene analysis of 161 sequence changes provides evidence for role of spatial constraint and regulatory elements on variant-induced splicing impact

We investigated the role of TP53 splicing regulatory elements (SREs) using exons 3 and 6 and their downstream introns as models. Minigene microdeletion assays revealed four SRE-rich intervals: c.573_598, c.618_641, c.653_669 and c.672+14_672 + 36.
Canson, D., Elena Bueno-Martínez, Miguel de la Hoya, Eladio A. Velasco-Sampedro, Spurdle, Amanda B., Llinares-Burguet, Inés, Inés Llinares-Burguet, Fortuno, C., Bueno-Martínez, Elena, Velasco, Eladio, Sanoguera-Miralles, Lara, Daffodil M. Canson, Cristina Fortuno, Amanda B. Spurdle, Lara Sanoguera-Miralles, Hoya, Miguel de la   +15 more
core   +1 more source

Clinicopathologic Characteristics of Somatic <i>TP53</i> Mutations in Philadelphia Chromosome-Negative Myeloproliferative Neoplasms: A Systematic Review. [PDF]

EJHaem
Aldapt M, Kaddoura R, Saleh AO, Najim M, Salem A, Al-Mashdali AF, Muthanna B, Aweer RA, Rabadi M, Mohamed SF.   +9 more
europepmc   +1 more source

Extending MET-TRIB3 axis research in hepatocellular carcinoma: Immune contexture and patient subgroups: Letter to the editor on “MET promotes hepatocellular carcinoma development through the promotion of TRIB3-mediated FOXO1 degradation” [PDF]

Clinical and Molecular Hepatology
Lei Wu, Ning Liu, Pengyuan Song, Meili Sun   +3 more
doaj   +1 more source

Dynamic Changes of ctDNA-Based MRD and Genomic Mutations Predict Prognosis in ESCC Treated With Definitive Radiotherapy. [PDF]

Cancer Sci
Liu S, Wang Q, Han C, Li X, Cheng R, Liu L, Dong H, Ren X, Zhen S, Wang L.   +9 more
europepmc   +1 more source

TP53 Loss Elevates NF-κB-IFN-β-MHC-Ia Signaling to Promote NK Cell Resistance in Osteosarcoma. [PDF]

Adv Sci (Weinh)
Qin G, Yeung CK, Yi Y, Zheng D, Ye M, Chio CC, Wu J, Fu S, Deng CX, Xu RH.   +9 more
europepmc   +1 more source

Embryonic and somatic mutations of gene TP53

, 2007
Našli jsme tři dosud nepopsané konstitutivní mutace TP53 (rodina III - Asp281Gly, rodina VI - Glu286Lys a rodina XI - Arg181Pro). Další čtyři rodiny nesly opakující se mutace, většinou v CpG dinukleotidech.
Procházková, Kamila
core  

Extranodal Organ Involvement in Chronic Lymphocytic Leukemia: Clinical Features and Outcomes With Bruton Tyrosine Kinase and BCL-2 Inhibitors. [PDF]

Cancer Med
Schulze FJ, Shumilov E, Behringer A, Kerkhoff A, Eckhardt M, Bätker S, Maulhardt M, Lenz G, Pohlmann A.   +8 more
europepmc   +1 more source

Lenalidomide Exposure and <i>TP53</i>-Mutated Myelodysplastic Syndromes/Neoplasms. [PDF]

Curr Oncol
Katamesh B, Shallis RM.
europepmc   +1 more source

p53 in Canine Mammary Tumors: From Molecular Pathogenesis to Biomarker Applications and Comparative Oncology. [PDF]

Vet Sci
Wang Z, Qin Y, Zeng Y, Liao S, Tao X, Liu X.   +5 more
europepmc   +1 more source

High-grade serous ovarian cancer is associated with increased TP53 mutation burden in uterine lavage. [PDF]

NPJ Precis Oncol
Heinzl N, Ghezelayagh TS, Wang G, Kohrn BF, Katz R, Coombes C, Smith TH, Norgaard ZK, Lo FY, Schmidt EK, Higgins JE, Valentine CC, Filipits M, Romanens L, Labidi-Galy I, Postl M, Grimm C, Cibula D, Dostálek L, Frühauf F, Jelenek G, Plch M, Fabian P, Mustea A, Condic M, Pristauz-Telsnigg G, Tamussino K, Bouda J, Brambs CE, O'Toole S, Bischof K, Grill S, Rosenthal AN, Vanderstichele A, Oppelt P, Rinda Soong T, Norquist BM, Salk JJ, Zeillinger R, Speiser P, Risques RA.   +40 more
europepmc   +1 more source