Results 131 to 140 of about 5,467 (204)

Genetic Determinants of Hematopoietic Toxicity Risk in Thai Pediatric Patients Undergoing 6-Mercaptopurine Treatment. [PDF]

Clin Transl Sci
Khaeso K, Chainansamit SO, Kuwatjanakul P, Komvilaisak P, Nakkam N, Suwannaying K, Vannaprasaht S, Dornsena A, Tassaneeyakul W.   +8 more
europepmc   +1 more source

Model-based clinical utility of pharmacogenetic testing and its potential population impact on the use of essential medicines in Zimbabwe. [PDF]

Front Pharmacol
Mazhindu TA, Chikwambi Z, Grimes KV, Borok MZ, Ndlovu N, Masimirembwa C.   +5 more
europepmc   +1 more source

Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between TPMT/NUDT15 and thiopurines

The Dutch Pharmacogenetics Working Group (DPWG) describes gene-drug interactions to facilitate pharmacogenetic implementation in clinical practice. The current guideline describes the gene-drug interactions for TPMT, NUDT15 and thiopurines (azathioprine,
Nijenhuis, Marga, Rongen, Gerard A.P.J.M., Houwink, Elisa J.F., Buunk, Anne Marie, Touw, Daan J., Risselada, Arne, Apotheek Klinische Farmacie, Coenen, Marieke J.H., Guchelaar, Henk Jan, Deneer, Vera H.M., van Schaik, Ron H.N., de Boer-Veger, Nienke J., van Westrhenen, Roos, Circulatory Health, Swen, Jesse J., Soree, Bianca   +15 more
core  

Comprehensive overview of the global pharmacogenetic and functional variability in NUDT15. [PDF]

Hum Genomics
Zhou Y, Lauschke LM, Lauschke VM.
europepmc   +1 more source

Prevalence of TPMT and NUDT15 diplotypes in Mexican children with B-cell acute lymphoblastic leukemia. [PDF]

Pharmacogenet Genomics
Garcia-Solorio J, Molina-Garay C, Sánchez-Martínez VJ, Villegas-Torres BE, Campos-Perez I, Jiménez-Olivares M, Flores-Espino F, Casique-Aguirre D, Núñez-Enriquez JC, Flores-Lujano J, Mata-Rocha M, Peñaloza-Gonzalez JG, Olivares-Villalpando VH, Baños-Lara MDR, García-Soto Á, Galván-Díaz CA, Olaya-Vargas A, Solano-Cardozo M, Garrido-Hernández MÁ, Luna-Silva NC, Cano-Cuapio LS, Carrillo-Sanchez K, Flores-Lagunes LL, Mendoza-Caamal EC, González-Osnaya V, Pelayo-Camacho R, Mejía-Arangure JM, Yang JJ, Alaez-Verson C.   +28 more
europepmc   +1 more source

Pharmacogenomics of treatment toxicities in pediatric B-Cell ALL: toward safer precision therapy. [PDF]

Front Pharmacol
Lameri M, Kamergi T, Brahim A, Abdallah I, Mezzi N, Zerei S, Benkahla A, Chaabane M, Drira C, Felfel H, Ben Abdennebi Y, Khrouf MR, Amor D, Romdhane L, Chaker H.   +14 more
europepmc   +1 more source

Pharmacogenomics and Epigenetic Regulation Transforming Pediatric Precision Therapeutics. [PDF]

J Pers Med
Satyam SM, Prabhakar S, Densil T, Mohammed HT, Kumari R, El-Tanani M, Rehman A, Kharoufeh A, Dalbah M, Eltrabishi MTZM.   +9 more
europepmc   +1 more source

Pharmacogenomic impact and genetic architecture of toxicity in pediatric acute lymphoblastic leukemia induction therapy: an exploratory modeling approach. [PDF]

Front Pharmacol
Gutierrez-Cáceres C, Alarcón-Concha C, Aracena-Farías J, Torres E, Acuña I, Sandoval T, Silva P, Ormeño M, Oyarce V, Cerpa LC, Martínez MF.   +10 more
europepmc   +1 more source

Practical guide to implementing pre-emptive pharmacogenetic screening in routine pediatric oncology care. [PDF]

Pharmacogenomics
Bernsen EC, Hanff LM, Kouwenberg TW, Hagleitner MM, Tops BBJ, Biesot N, Hehir-Kwa JY, Huitema ADR, Diekstra MHM.   +8 more
europepmc   +1 more source

Validation of diagnostic screening test for pharmacogenomic targets for thiopurine drugs in indian pediatric acute lymphoblastic leukemia patients. [PDF]

Front Pharmacol
Joseph GT, Swain SK, Somwanshi T, Singh A, Kaur M, Kamal R, Dhanda H, Kumar P, Kaushik U, Noor B, Sharma S, Tanwar P, Zaheer S, Chaudhry S, Prabhakar P, Singh A, Rishi B, Misra A.   +17 more
europepmc   +1 more source