Protective Effects of Rapamycin on Trabecular Meshwork Cells in Glucocorticoid-Induced Glaucoma Mice
Frontiers in Pharmacology, 2020 Glucocorticoid-induced glaucoma (GIG) is a chronic optic neuropathy caused by systemic or topical glucocorticoid (GC) treatment, which could eventually lead to permanent vision loss.
Xiaolu Zhu +6 more
semanticscholar +1 more source
Oxidative damage and autophagy in the human trabecular meshwork as related with ageing.
PLoS ONE, 2014 Autophagy is an intracellular lysosomal degradation process induced under stress conditions. Autophagy also plays a major role in ocular patho-physiology. Molecular aging does occur in the trabecular meshwork, the main regulator of aqueous humor outflow,
Alessandra Pulliero +5 more
doaj +1 more source
Journal of Agromedicine and Medical Sciences (AMS), 2017 In primary open angle glaucoma, decrease of hyaluronic acid level is related to extracellular matrix deposition of trabecular meshwork. Extracellular matrix deposition will increase humor aqueous outflow resistance which in turn increase the intraocular ...
Cicih Komariah +2 more
doaj +1 more source
Association between Myopia, Biometry and Occludable Angle: The Jiangning Eye Study. [PDF]
PLoS ONE, 2016 Myopia subjects usually have long axial lengths and are predisposed to deep anterior chamber depths and open angles. Jiangning eye study is a randomized, population based study in Shanghai to determine whether myopia has an effect on the prevalence of ...
Xiaohong Liu +9 more
doaj +1 more source
Morphological changes in the iridocorneal angle and their relationship with intraocular pressure after infantile cataract surgery [PDF]
International Journal of Ophthalmology, 2022 AIM: To evaluate morphological changes in the iridocorneal angle after pediatric cataract surgery. METHODS: Children who underwent primary infantile cataract surgery were included and 64 eyes from 41 children, including 18 with unilateral cataracts (18 ...
Dan-Dan Wang +5 more
doaj +1 more source
Implantation of trabecular micro-bypass stent using a novel “landing strip” technique [PDF]
International Journal of Ophthalmology, 2017 AIM: To describe a novel technique of creating a landing strip within the trabecular meshwork to guide trabecular micro-bypass stent (iStent) implantation in patients who underwent phacoemulsification.
Cindy X. Zheng +5 more
doaj +1 more source
Trabecular meshwork gene expression after selective laser trabeculoplasty.
PLoS ONE, 2011 BackgroundTrabecular meshwork and Schlemm's canal are the tissues appointed to modulate the aqueous humour outflow from the anterior chamber. The impairment of their functions drives to an intraocular pressure increase.
Alberto Izzotti +4 more
doaj +1 more source
Histopathological changes in the trabecular meshwork in primary congenital glaucoma [PDF]
Am J Ophthalmol Case RepPurpose: To evaluate the morphological changes in the ex-vivo trabecular meshwork TM specimens from patients with primary congenital glaucoma. Methods: Five trabecular meshwork (TM) specimens obtained after microincisional trabeculectomy from 4 patients ...
Aparna Rao
europepmc +1 more source
RNA interference as a gene silencing therapy for mutant
Diagnostic Pathology, 2009 Background Primary open-angle glaucoma (POAG) is the most common form of glaucoma which is an irreversible blind leading disease and lacks effective remedies.
Sun Xinghuai +3 more
doaj +1 more source
Indian Journal of Ophthalmology, 2012 Purpose: To study ultrastructural changes of the trabecular meshwork in acute and chronic primary angle closure glaucoma (PACG) and primary open angle glaucoma (POAG) eyes by scanning electron microscopy.
Ramanjit Sihota +4 more
doaj +1 more source