Results 111 to 120 of about 164,752 (316)

Energy-efficient traffic engineering for future core networks [PDF]

open access: yesarXiv, 2012
A general problem formulation for energy-efficient traffic engineering for future core networks is presented. Moreover, a distributed heuristic algorithm that provides jointly load balancing and energy efficiency is proposed, approaching in this way the optimal network operation in terms of throughput and energy consumption.
arxiv  

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

open access: yesAdvanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin   +21 more
wiley   +1 more source

Multicast Traffic Engineering for Software-Defined Networks [PDF]

open access: yesarXiv, 2015
Although Software-Defined Networking (SDN) enables flexible network resource allocations for traffic engineering, current literature mostly focuses on unicast communications. Compared to traffic engineering for multiple unicast flows, multicast traffic engineering for multiple trees is very challenging not only because minimizing the bandwidth ...
arxiv  

The Nuclear Receptor NR1B1/RARα Arrests the Differentiation of Anti‐Tumor Effector Cytotoxic T Cells

open access: yesAdvanced Science, EarlyView.
RARα is highly expressed by differentiated effector and exhausted T cells and exerts a negative effect on effector T cell differentiation and the associated trafficking receptor switch. Upregulated RARα levels decrease the nuclear histone acetylase (HAT) activity, and this suppresses the expression of key Teff transcription factor BATF and trafficking ...
Patrick Niekamp   +5 more
wiley   +1 more source

DNA Origami‐Cyanine Nanocomplex for Precision Imaging of KRAS‐Mutant Pancreatic Cancer Cells

open access: yesAdvanced Science, EarlyView.
DNA origami‐cyanine (Do‐Cy) nanocomplexes are synthesized to selectively image KRAS‐mutant pancreatic cancer cells in the highly desmoplastic tumors. This study shows that the Do‐Cy nanocomplexes are preferentially internalized by cancer cells over other stroma cells via KRAS‐dependent macropinocytosis.
Hye‐ran Moon   +7 more
wiley   +1 more source

Enhancing Traffic Safety Analysis with Digital Twin Technology: Integrating Vehicle Dynamics and Environmental Factors into Microscopic Traffic Simulation [PDF]

open access: yesarXiv
Traffic safety is a critical concern in transportation engineering and urban planning. Traditional traffic safety analysis requires trained observers to collect data in the field, which is time-consuming, labor-intensive, and sometimes inaccurate. In recent years, microscopic traffic simulation, which simulates individual vehicles' movements within a ...
arxiv  

TRAF3IP3 Induces ER Stress‐Mediated Apoptosis with Protective Autophagy to Inhibit Lung Adenocarcinoma Proliferation

open access: yesAdvanced Science, EarlyView.
Schematic diagram of the working model of TRAF3IP3 in the coordination of ER stress and autophagy related apoptosis in lung cancer cells. Abstract TNF receptor‐associated factor 3 interacting protein 3 (TRAF3IP3/T3JAM) exhibits dual roles in cancer progression. While upregulated in most malignancies and critical for immune regulation.
Guang Zhao   +11 more
wiley   +1 more source

The multifactorial aquaculture‐related COVID‐19 shock in Benin, West Africa: A socio‐economic perspective of mitigating the disruptive impacts on the small‐scale and subsistence producers

open access: yesAquaculture, Fish and Fisheries, Volume 2, Issue 6, Page 507-521, December 2022., 2022
Graphical Abstract This study deals with a timely topic, COVID‐19, whose impacts on aquaculture have never been quantified in Benin. Direct discussions were held with aquaculture producers to understand how they are feeling the impact of the pandemic on their business.
Toundji Olivier Amoussou   +7 more
wiley   +1 more source

Requirements for Traffic Engineering Over MPLS [PDF]

open access: bronze, 1999
D.O. Awduche   +4 more
openalex   +1 more source

Structural Diversity of Mitochondria in the Neuromuscular System across Development Revealed by 3D Electron Microscopy

open access: yesAdvanced Science, EarlyView.
Mitochondria across the entire neuromuscular system have been comprehensively reconstructed at different developmental stages using 3D electron microscopy. Fundamental structural principles related to synaptic function are preserved across development, and these morphologies are adapted to ensure effective neural circuit function.
J. Alexander Bae   +9 more
wiley   +1 more source

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