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Bacterial translocation promotes trained immunity
ImmunityCan bacteria that breach mucosal barriers drive long-lasting changes in immunity? In this issue of Immunity, Robles-Vera et al. describe how, in the context of colitis, bacteria breaching the intestinal barrier reprogram precursors in the bone marrow via Mincle-dependent signaling.
Maria Francesca Viola, Elvira Mass
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Training pharmacy technicians to administer immunizations
Journal of the American Pharmacists Association, 2018To evaluate the effectiveness of an immunization training program for pharmacy technicians on technicians' self-reported confidence, knowledge, and number of vaccines administered.A one-group pre- and posttest study was conducted with certified pharmacy technicians from Albertsons and Safeway community pharmacies in Idaho.
Kimberly C, McKeirnan +3 more
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Vaccinations have significantly reduced mortality from infectious diseases by preparing the immune system for pathogens without causing illness. In addition to specific protection, some vaccines can also have non-specific effects (NSE), offering broader protection against various infections.
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Altered Cellular Metabolism Drives Trained Immunity
Trends in Endocrinology & Metabolism, 2018Exposing innate immune cells to an initial insult induces a long-term proinflammatory response due to metabolic and epigenetic alterations which encompass an emerging new concept called trained immunity. Recent studies provide novel insights into mechanisms centered on metabolic reprogramming which induce innate immune memory in hematopoietic stem ...
Sohrabi, Yahya +2 more
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Trained immunity in allergic asthma
Journal of Allergy and Clinical Immunology, 2023openaire +2 more sources