Results 51 to 60 of about 66,996 (265)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Adaptive NMPC for trajectory tracking of 4WID-4WIS mobile robot

Smart Agricultural Technology
This paper investigates the trajectory tracking control problem of four-wheel independently driven and steered (4WID-4WIS) mobile robots for operation in dwarf dense orchards. A trajectory tracking method based on Nonlinear Model Predictive Control (NMPC)
Song Bi, Zirong Xiao, Zhijun Li, Ang Bi, Yifei Xiao   +4 more
doaj   +1 more source

Time-varying dynamic modeling and trajectory tracking control for variable-load unmanned aerial vehicle [PDF]

Frontiers of Agricultural Science and Engineering
The dynamic variation issues of variable-load unmanned aerial vehicle (UAV) used in agricultural plant protection activities was addressed by a disturbance-resistant control system based on PD (proportional-derivative) sliding mode control. First, a time-
Xin ZHANG, Shuting XU, Wenjie CHANG, Feng KANG   +3 more
doaj   +1 more source

A Vehicle Trajectory Tracking Method With a Time-Varying Model Based on the Model Predictive Control

IEEE Access, 2020
The vehicle trajectory tracking algorithm is one of the key and difficult issues of intelligent driving technologies. In current control algorithms for the vehicle trajectory tracking, there are three main assumptions: the standard working condition for ...
Xiaohua Song, Yiming Shao, Zhihua Qu
doaj   +1 more source

Dynamic modeling and trajectory tracking control of unmanned tracked vehicles

Robotics and Autonomous Systems, 2018
Abstract Tracked vehicles have inherent advantages over wheeled vehicles, as the former provide stable locomotion on loose and uneven terrain. However, compared with the latter, the slippage generated due to the complex, nonlinear track-terrain interactions during skid-steering to follow a curve, brings about difficulties preventing the accurate ...
Ting Zou, Jorge Angeles, Ferri Hassani
openaire   +2 more sources

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Frictional forces and torques compensation based cascaded sliding-mode tracking control for an uncertain omnidirectional mobile robot

Measurement + Control, 2022
The work presented here deals with the trajectory-tracking control of omnidirectional mobile robots using a novel robust control technique. The aim is to achieve good tracking performance in the presence of frictional forces and torques, uncertainties ...
Hsiu-Ming Wu, Mansour Karkoub
doaj   +1 more source