Results 51 to 60 of about 79,894 (308)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A Prognosis Technique Based on Improved GWO-NMPC to Improve the Trajectory Tracking Control System Reliability of Unmanned Underwater Vehicles

, 2023
The dynamics model of the unmanned underwater vehicle (UUV) system is highly nonlinear, multi-degree-of-freedom, strongly coupled, and time-varying. Its motion control has been a complex problem due to the unknown information about and the uncertainty of
Wenyang Gan, Tianxing Xia, Zhenzhong Chu
core   +1 more source

Straight-Line Trajectory Tracking Control of Unmanned Sailboat Based on NMPC Velocity and Heading Joint Control

Journal of Marine Science and Engineering
This study proposes a trajectory tracking approach for unmanned sailboats that integrates velocity and heading control using nonlinear model predictive control (NMPC).
Kai Liu, Jiancheng Yu, Wentao Zhao
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Research on the trajectory tracking of a curved road in an active lane change scenario based on model predictive control algorithm

Advances in Mechanical Engineering, 2023
In this paper, a control method for trajectory planning and tracking of an intelligent vehicle is proposed. In terms of trajectory planning, a trajectory planning method for curved lane changes is designed based on conventional lane change trajectory ...
Wei Wang, Fufan Qu, Chong Guo, Wenbo Li
doaj   +1 more source

Trajectory Tracking Coordinated Control of 4WID-4WIS Electric Vehicle Considering Energy Consumption Economy Based on Pose Sensors

Sensors, 2023
In order to improve the stability and economy of 4WID-4WIS (four-wheel independent drive—four-wheel independent steering) electric vehicles in trajectory tracking, this paper proposes a trajectory tracking coordinated control strategy considering energy ...
Yiran Qiao, Xinbo Chen, Zhen Liu
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Real-Time Trajectory Replanning and Tracking Control of Cable-Driven Continuum Robots in Uncertain Environments

Actuators
To address trajectory tracking of cable-driven continuum robots (CDCRs) in the presence of obstacles, this paper proposes an integrated control framework that combines online trajectory replanning, obstacle avoidance, and tracking control.
Yanan Qin, Qi Chen
doaj   +1 more source

Pick–and–Place Trajectory Planning and Robust Adaptive Fuzzy Tracking Control for Cable–Based Gangue–Sorting Robots with Model Uncertainties and External Disturbances

Machines, 2022
A suspended cable–based parallel robot (CBPR) composed of four cables and an end–grab is employed in a pick–and–place operation of moving target gangues (MTGs) with different shapes, sizes, and masses.
Peng Liu, Haibo Tian, Xiangang Cao, Xinzhou Qiao, Li Gong, Xuechao Duan, Yuanying Qiu, Yu Su   +7 more
doaj   +1 more source