A simple and rapid spectrophotometric method for the determination of trans-chalcone in raw-material and topical formulation [PDF]
, 2023 Trans-chalcone (TC) is a flavonoid precursor characterized by a wide spectrum of action, with anti-inflammatory and antioxidant effects. However, no validated methods are available in official compendia for the analysis of this substance.
Renata M. Martínez +6 more
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Journal of Physiological InvestigationIschemia-reperfusion (IR) injury remains a pivotal contributor to myocardial damage following acute coronary events and revascularization procedures. Phosphoinositide 3-kinase (PI3K), a key mediator of cell survival signaling, plays a central role in ...
Jing Wang +3 more
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The synthesis of chiral β-naphthyl-β-sulfanyl ketones via enantioselective sulfa-Michael reaction in the presence of a bifunctional cinchona/sulfonamide organocatalyst [PDF]
Beilstein Journal of Organic Chemistry, 2021 Cinchona alkaloid-derived organocatalysts are widely employed in various asymmetric transformations, yielding products with high enantiopurity. In this respect, a bifunctional quinine-derived sulfonamide organocatalyst was developed to catalyze the ...
Deniz Tözendemir, Cihangir Tanyeli
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Development and validation of a UV–Vis spectrophotometric method for estimation of total content of chalcone [PDF]
MethodsXIn this study, a straightforward spectrophotometric method was developed for quantifying the total content of chalcones in a sample. The method exhibits linearity, accuracy, precision, repeatability, and enables the estimation of total chalcone content ...
J.R.S. Botelho +4 more
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Photochemistry of 5-Hydroxy-4'-Dimethylaminoflavylium in the presence of SDS micelles. The role of metastable states of flavylium cation-quinoidal base and trans-chalcones [PDF]
, 2020 UIDB/50006/2020 UIDP/50006/2020 PTDC/QUI-OUT/29013/2017 SFRH/BD/143309/2019 SFRH/BD/146549/2019 MEX/Ref. 288188 IF/00225/2015The multistate of species originated by the compound 5-hydroxy-4′-dimethylaminoflavylium was studied in the presence of sodium ...
Paula Araújo +6 more
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Trans-chalcone suppresses tumor growth mediated at least in part by the induction of heme oxygenase-1 in breast cancer. [PDF]
Toxicol Res, 2021 Komoto TT +6 more
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Trans-Chalcone Plus Baicalein Synergistically Reduce Intracellular Amyloid Beta (Aβ42) and Protect from Aβ42 Induced Oxidative Damage in Yeast Models of Alzheimer's Disease. [PDF]
Int J Mol Sci, 2021 Dhakal S +3 more
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Trans-Chalcone (1-3-diphenyl-2-propen-1-one) as a Therapeutic Candidate in Joint Inflammation via Reduction of TNF-α, IL-1β, IL-6, and IL-17 in Rodents: An In Vivo Study by RT-PCR and ELISA analysis. [PDF]
ACS OmegaJabbar Z +8 more
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The natural compound trans‐chalcone induces programmed cell death in Arabidopsis thaliana roots [PDF]
Plant, Cell & Environment, 2012 ABSTRACTChalcone (1,3‐diphenyl‐2‐propen‐1‐one) is an aromatic ketone precursor of important molecules in plants such as flavonoids or anthocyanins. Its phytotoxicity has been demonstrated on different plant species, but to date little is known about the mechanisms of action of this secondary metabolite at plant cellular level.
Carla Díaz‐Tielas +4 more
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The effects of trans -chalcone and chalcone hydrate on the growth of Babesia and Theileria [PDF]
The effects of trans-chalcone and chalcone 4 hydrate on the growth of Babesia and Theileria, 2018 application/pdf BACKGROUND: Chemotherapy is a principle tool for the control and prevention of piroplasmosis. The search for a new chemotherapy against Babesia and Theileria parasites has become increasingly urgent due to the toxic side effects of and developed resistance to the current drugs.
Gaber El‐Saber Batiha +6 more
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