Results 131 to 140 of about 1,962,599 (295)
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins +9 more
wiley +1 more source
Angewandte Chemie, EarlyView.Genome mining of atypical condensation (C) domains leads to the discovery of myxoglucamides, glycolipopeptides featuring an unprecedented vinyl‐substituted, α‐oxidized γ‐amino acid. Biosynthetic studies reveal a discrete C‐domain‐like O‐acyltransferase, a β‐hydroxylation‐dependent chain‐extension checkpoint, and an unusual pathway for γ‐amino acid ...
Tingting Wang +10 more
wiley +2 more sources
Animal Models and Experimental Medicine, EarlyView.Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley +1 more source
Food, Fatty Acids and Antioxidants Intake and their Associations with Atopic disease in Adults [PDF]
, 2011 It was hypothesized that high fat consumption, specifically from polyunsaturated fatty acids, may be positively related to atopic disease prevalence.
Trak-Fellermeier, María Angélica
core +1 more source
Advanced NanoBiomed Research, EarlyView.Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi +6 more
wiley +1 more source
Micronutrients, omega-3 fatty acids and cognitive performance in Indian schoolchildren [PDF]
, 2009 In developing countries, approximately 30-40% of school-age children suffer from iodine and iron deficiencies. Poverty and consumption of monotonous diets are underlying causes of inadequate intakes of micronutrients and omega-3 fatty acids and may have ...
Eilander, J.H.C.
core
Trans fatty acids and coronary artery disease
Open Access Journal of Clinical Trials, 2010 Jocelyne R BenatarGreen Lane Cardiovascular Service, Auckland City Hospital, Auckland, New ZealandAbstract: There has been a significant increased consumption of trans fats in the developed world as we have embraced processed and take away foods in our ...
Jocelyne R Benatar
doaj
Food Safety and RiskThe physicochemical characteristics and fatty acid composition of bakery products are key determinants of nutritional quality and stability. This study aimed to generate baseline data on unlabeled bakery products in Bangladesh by evaluating their ...
Azizur Rahman +7 more
doaj +1 more source
Impact of fatty acid status on immune function of children in low-income countries.
, 2011 In vitro and animal studies point to numerous mechanisms by which fatty acids, especially long-chain polyunsaturated fatty acids (LCPUFA), can modulate the innate and adaptive arms of the immune system.
Liandré van der Merwe +3 more
core +1 more source