Results 141 to 150 of about 94,754 (254)

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu   +23 more
wiley   +1 more source

Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise   +3 more
wiley   +1 more source

Dietary intake of trans fatty acids and breast cancer risk in 9 European countries. [PDF]

open access: yesBMC Med, 2021
Matta M   +37 more
europepmc   +1 more source

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

open access: yesBMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang   +7 more
wiley   +1 more source

Industrial Trans Fatty Acids Promote the Development of Food Allergy in a Mouse Model. [PDF]

open access: yesAllergy Asthma Immunol Res
Fu W   +10 more
europepmc   +1 more source

Olive Oil Improves While Trans Fatty Acids Further Aggravate the Hypomethylation of LINE-1 Retrotransposon DNA in an Environmental Carcinogen Model. [PDF]

open access: yesNutrients, 2022
Szabo L   +13 more
europepmc   +1 more source

How developmental stressors affect mitochondrial respiratory function: a systematic review and meta‐analysis

open access: yesBiological Reviews, EarlyView.
ABSTRACT The environmental conditions organisms experience during early development can have powerful and sustained effects on morphology, physiology, behaviour, and performance. Such developmental effects can influence reproductive success, survival, and life‐history strategies and can be transmitted across generations (i.e.
Ondi L. Crino   +7 more
wiley   +1 more source

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