Results 111 to 120 of about 3,753,914 (306)
Genetic Variation in Transcription Factor Binding Sites
International Journal of Molecular Sciences, 2023 The interaction between transcription factors (TFs) and DNA is the core process that determines the state of a cell’s transcriptome [...]
openaire +2 more sources
Plant Transcription Factors @ uni-potsdam.de [PDF]
, 2007 We present the Plant Transcription Factor Database (PlnTFDB), and the putative complete set of TFs in the algae _Chlamydomonas reinhardtii_, _Ostreococcus tauri_ and the vascular plants _Oryza sativa_ and _Arabidopsis ...
Slobodan Ruzicic +3 more
core +1 more source
Novel Genetic Diagnoses in Septo-Optic Dysplasia
, 2022 Septo-optic dysplasia (SOD) is a developmental phenotype characterized by midline neuroradiological anomalies, optic nerve hypoplasia, and pituitary anomalies, with a high degree of variability and additional systemic anomalies present in some cases ...
Mohit Maheshwari +15 more
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Nature Communications, 2017 Covariance of gene expression pairs is due to a combination of shared genetic and environmental factors. Here the authors estimate the genetic correlation between highly heritable pairs and identify transcription factor control and chromatin interactions
Samuel W. Lukowski +17 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Transcription Factors in Schizophrenia: A Current View of Genetic Aspects
, 2016 Background: Schizophrenia is a polygenic mental disorder with about 80% heritability. Growing evidence indicated that synaptic dysfunctions contribute to SCZ etiopathogenesis.The context and purpose of the study: Transcription factors play an important ...
Roksana Zakharyan, Zakharyan Roksana
core +1 more source
Using temporal correlation in factor analysis for reconstructing transcription factor activities [PDF]
, 2008 Two-level gene regulatory networks consist of the transcription factors (TFs) in the top level and their regulated genes in the second level. The expression profiles of the regulated genes are the observed high-throughput data given by experiments such ...
Wernisch, Lorenz +3 more
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Genetic determinants of NEIL2 transcription [PDF]
, 2008 The human genome is constantly damaged by reactive oxygen species (ROS) which produce a multitude of oxidative DNA lesions that can lead to mutations, genomic instability, and ultimately, to the development of cancer and other diseases.
Carla Jean Kinslow
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RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
A new direction for farm animal genetic resources [PDF]
, 2009 In September 2007, the International Technical Conference on Animal Genetic Resources for Food and Agriculture was held in Interlaken, Switzerland. Two important documents aiming at preventing the genetic erosion of farm animal biodiversity and promoting
Kantanen, Juha
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