Results 111 to 120 of about 1,088,355 (314)

The splicing factor proline-glutamine rich (SFPQ/PSF) is involved in influenza virus transcription.

, 2011
The influenza A virus RNA polymerase is a heterotrimeric complex responsible for viral genome transcription and replication in the nucleus of infected cells. We recently carried out a proteomic analysis of purified polymerase expressed in human cells and
Juan Ortín, Landeras-Bueno, Sara, Jorba, N, Sara Landeras-Bueno, Ortín Juan, Pérez-Cidoncha, Maite, Pérez-Cidoncha, M, Núria Jorba, Landeras-Bueno Sara, Pérez-Cidoncha Maite, Landeras-Bueno, S, Ortín, J, Ortín, Juan, Jorba, Núria, Maite Pérez-Cidoncha, Jorba Núria   +15 more
core   +1 more source

A conserved phosphorylation site regulates the transcriptional function of ETHYLENE-INSENSITIVE3-like1 in tomato [PDF]

, 2011
ETHYLENE-INSENSITIVE3/ETHYLENE-INSENSITIVE3-like (EIN3/EIL) transcription factors are important downstream components of the ethylene transduction pathway known to regulate the transcription of early ethylene-responsive genes in plants.
Z. Li, J. Li, Li, Zhengguo, M. Bouzayen, Tang, Ling, M. Zouine, L. Tang, Zouine, Mohamed, Y. Yang, Yang, Yingwu, Li, Ji, Bouzayen, Mondher   +11 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

ReprOlive: a Database with Linked Data for the Olive Tree (Olea europaea L.) Reproductive Transcriptome

Frontiers in Plant Science, 2015
Plant reproductive transcriptomes have been analysed in different species due to the agronomical and biotechnological importance of plant reproduction.
Rosario M. Carmona, Rosario M. Carmona, Adoración eZafra, Pedro eSeoane, Antonio J. Castro, Darío eGuerrero-Fernández, Trinidad eCastillo-Castillo, Ana eMedina-García, Francisco M Cánovas, José eAldana-Montes, Ismael eNavas-Delgado, Juan De Dios eAlché, M. Gonzalo eClaros   +12 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genesis of ancestral haplotypes: RNA modifications and reverse transcription–mediated polymorphisms

, 2011
Understanding the genesis of the block haplotype structure of the genome is a major challenge. With the completion of the sequencing of the Human Genome and the initiation of the HapMap project the concept that the chromosomes of the mammalian genome are
Stewart, B.J., Carnegie, P., Pain, G.N., Dawkins, R.L., Steele, E.J., Williamson, J.F., Lindley, R.A., Millman, J.A., Lester, S.   +8 more
core  

Orchestrated transcription of biological processes in the marine picoeukaryote Ostreococcus exposed to light/dark cycles [PDF]

, 2010
Background: Picoeukaryotes represent an important, yet poorly characterized component of marine phytoplankton. The recent genome availability for two species of Ostreococcus and Micromonas has led to the emergence of picophytoplankton comparative ...
Bouget, F-Y, Mosser, J, Bouget, FY, Beline Jesson, Corellou, F, Smith Jim Q, Annabelle Monnier, Jesson, Béline, Monnier, Annabelle, Corellou, Florence, Corellou Florence, Smith, Jim, Q., Monnier Annabelle, Liverani, S, Bouvet, Régis, Monnier, A, Smith, Jim,, Regis Bouvet, Jim Q Smith, Florence Corellou, Francois-Yves Bouget, Smith, JQ, Bouvet, R, Jesson, B, Jean Mosser, Silvia Liverani, Mosser, Jean, Smith, J. Q., Jesson Béline, Liverani Silvia, Bouvet Régis, Mosser Jean, Bouget François-Yves, Liverani, Silvia, Bouget, François-Yves   +34 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Evolving concurrent Petri net models of epistasis

, 2010
A genetic algorithm is used to learn a non-deterministic Petri netbased model of non-linear gene interactions, or statistical epistasis. Petri nets are computational models of concurrent processes.
Beretta, Lorenzo, Mayo, Michael
core   +1 more source

Continuous-time modeling of cell fate determination in Arabidopsis flowers [PDF]

, 2010
Background The genetic control of floral organ specification is currently being investigated by various approaches, both experimentally and through modeling.
Angenent, G.C., Richard GH Immink, Molenaar, J., Maarten de Gee, Roeland CHJ van Ham, Ham, R.C.H.J., van, Immink, R.G.H., van Mourik, S., van Dijk, A.D.J., Kaufmann, K., Mourik, S., van, de Gee, M., Dijk, A.D.J., van, Simon van Mourik, Gee, M., de, van Ham, R.C.H.J., Jaap Molenaar, Kerstin Kaufmann, Aalt DJ van Dijk, Gerco C Angenent   +19 more
core   +1 more source