Results 191 to 200 of about 4,501,017 (312)

Quantum-inspired logic for advanced Transcriptional Programming. [PDF]

Nucleic Acids Res
Milner PT, Kim D, Wilson CJ.
europepmc   +1 more source

Genetic induction and mechanochemical propagation of a morphogenetic wave

Nature, 2019
Anaïs Bailles, Claudio Collinet, J. Philippe, P. Lenne, E. Munro, Thomas Lecuit   +5 more
semanticscholar   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Genomics control of biostimulant-induced stress tolerance and crop yield enhancement. [PDF]

Plant J
Gechev T.
europepmc   +1 more source

A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation

Development, 2015
E. Kozhemyakina, A. Lassar, E. Zelzer
semanticscholar   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Genetic and Functional Dissection of the NFKB2 Gene: Implications for Milk Fatty Acid Biosynthesis in Dairy Cattle. [PDF]

FASEB J
Shi L, Guo Z, Shen N, Li C, Han B, Sun D.   +5 more
europepmc   +1 more source

Function of MYB domain transcription factors in abiotic stress and epigenetic control of stress response in plant genome

Plant Signalling & Behavior, 2016
Sujit Roy
semanticscholar   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Glutamic Acid at Position 343 in PB2 Contributes to the Virulence of H1N1 Swine Influenza Virus in Mice. [PDF]

Viruses
Wang Y, Zhong Q, Meng F, Cheng Z, Zhang Y, Song Z, Zhang Y, Feng Z, Zhai Y, Chen Y, Qiao C, Yang H.   +11 more
europepmc   +1 more source