Results 11 to 20 of about 2,030,096 (261)
Transcriptional and Post-Transcriptional Regulation of Autophagy [PDF]
Cells, 2022 Autophagy is a widely conserved process in eukaryotes that is involved in a series of physiological and pathological events, including development, immunity, neurodegenerative disease, and tumorigenesis. It is regulated by nutrient deprivation, energy stress, and other unfavorable conditions through multiple pathways.
Qiuqin Ma +5 more
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Boosting transcription by transcription: enhancer-associated transcripts [PDF]
Chromosome Research, 2013 Enhancers are traditionally viewed as DNA sequences located some distance from a promoter that act in cis and in an orientation-independent fashion to increase utilization of specific promoters and thereby regulate gene expression. Much progress has been made over the last decade toward understanding how these distant elements interact with target ...
Emily M, Darrow, Brian P, Chadwick
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Dynamics of transcriptional and post-transcriptional regulation [PDF]
Briefings in Bioinformatics, 2020 AbstractDespite gene expression programs being notoriously complex, RNA abundance is usually assumed as a proxy for transcriptional activity. Recently developed approaches, able to disentangle transcriptional and post-transcriptional regulatory processes, have revealed a more complex scenario.
Mattia Furlan +2 more
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Transcriptional enhancers: Transcription, function and flexibility [PDF]
Transcription, 2016 Active transcriptional enhancers are often transcribed to eRNAs, whose changing levels mirror those of the target gene mRNA. We discuss some of the reported functions of these eRNAs and their likely diversity to allow utilization of distinct cis regulatory regions to enhance transcription in diverse developmental and cellular contexts.
Philippa, Melamed +3 more
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Transcriptional regulation of haematopoietic transcription factors [PDF]
Stem Cell Research & Therapy, 2011 The control of differential gene expression is central to all metazoan biology. Haematopoiesis represents one of the best understood developmental systems where multipotent blood stem cells give rise to a range of phenotypically distinct mature cell types, all characterised by their own distinctive gene expression profiles.
Wilson, Nicola K +3 more
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Transcriptional Activation: Tuning-up transcription [PDF]
Current Biology, 1995 Eukaryotic transcription is a complex process, and recent results identify multiple steps that need to be stimulated to activate transcription, one of which is a change in conformation of the general transcription factor TFIIB.
Sheldon, Michael, Danny, Reinberg
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Frontiers in Cell and Developmental Biology, 2023 The Polybromo-associated BAF (BRG1- or BRM-associated factors) (PBAF) chromatin-remodeling complex is essential for transcription in mammalian cells.
Nataliya V. Soshnikova +12 more
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Biology Open, 2020 The mammalian PBAF subfamily of SWI/SNF chromatin remodeling complexes plays a wide role in the regulation of gene expression. PHF10 is a subunit of the signature module of PBAF, responsible for its interaction with chromatin.
Andrey A. Sheynov +5 more
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Microbiology Spectrum, 2022 Bg_9562, a prophage tail-like protein was earlier shown to be required for bacterial mycophagy by Burkholderia gladioli strain NGJ1. The purified protein exhibited broad-spectrum antifungal activity; however, the structural and mechanistic details vis-à ...
Pankaj Kumar Sahoo +5 more
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Transcription and post-transcriptional regulation of spermatogenesis [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2010 Spermatogenesis in mammals is achieved by multiple players that pursue a common goal of generating mature spermatozoa. The developmental processes acting on male germ cells that culminate in the production of the functional spermatozoa are regulated at both the transcription and post-transcriptional levels. This review addresses recent progress towards
Anilkumar, Bettegowda +1 more
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