Results 31 to 40 of about 2,746,686 (254)

Visual analysis for drum sequence transcription [PDF]

, 2007
A system is presented for analysing drum performance video sequences. A novel ellipse detection algorithm is introduced that automatically locates drum tops.
McGuinness, Kevin, O'Connor, Noel E., Gillet, Olivier, Richard, Gaël   +3 more
core   +3 more sources

Lysine-Specific Histone Demethylase 1A Regulates Macrophage Polarization and Checkpoint Molecules in the Tumor Microenvironment of Triple-Negative Breast Cancer

Frontiers in Immunology, 2019
Macrophages play an important role in regulating the tumor microenvironment (TME). Here we show that classical (M1) macrophage polarization reduced expression of LSD1, nuclear REST corepressor 1 (CoREST), and the zinc finger protein SNAIL.
Abel H. Y. Tan, WenJuan Tu, Robert McCuaig, Kristine Hardy, Thomasina Donovan, Sofiya Tsimbalyuk, Jade K. Forwood, Sudha Rao   +7 more
doaj   +1 more source

The Role of the Histone Variant H2A.Z in Metazoan Development

Journal of Developmental Biology, 2022
During the emergence and radiation of complex multicellular eukaryotes from unicellular ancestors, transcriptional systems evolved by becoming more complex to provide the basis for this morphological diversity.
Yasmin Dijkwel, David J. Tremethick
doaj   +1 more source

An R2R3 MYB transcription factor associated with regulation of the anthocyanin biosynthetic pathway in Rosaceae [PDF]

, 2010
Background The control of plant anthocyanin accumulation is via transcriptional regulation of the genes encoding the biosynthetic enzymes. A key activator appears to be an R2R3 MYB transcription factor.
Wang, Kui-Lin, Kortstee, A.J., Tony K McGhie, McGhie Tony K, Hellens, R.P., Espley Richard V, Hellens Roger P, Grafton, Karryn, Espley, Richard V., Karryn Grafton, Karunairetnam, Sakuntala, Andrew C Allan, Kortstee, Anne, Roger P Hellens, Allan, A.C., Allan, Andrew C., McGhie, T.K., Richard V Espley, Kortstee Anne, Allan Andrew C, Espley, R.V., Sakuntala Karunairetnam, Karunairetnam Sakuntala, Grafton Karryn, McGhie, Tony K., Lin-Wang Kui, Bolitho, Karen, Karen Bolitho, Anne Kortstee, Bolitho Karen, Hellens, Roger P., Lin-Wang, Kui, Kui Lin-Wang   +32 more
core   +2 more sources

The Rho-Dependent Transcription Termination Is Involved in Broad-Spectrum Antibiotic Susceptibility in Escherichia coli

Frontiers in Microbiology, 2020
One of the major ways of acquiring multidrug resistance in bacteria is via drug influx and efflux pathways. Here, we show that E. coli with compromised Rho-dependent transcription termination function has enhanced broad-spectrum antibiotic susceptibility,
Md. Hafeezunnisa, Md. Hafeezunnisa, Ranjan Sen   +2 more
doaj   +1 more source

Many Distinct Ways Lead to Drug Resistance in BRAF- and NRAS-Mutated Melanomas

Life, 2021
Advanced melanoma is a relentless tumor with a high metastatic potential. The combat of melanoma by using the targeted therapy is impeded because several major driver mutations fuel its growth (predominantly BRAF and NRAS).
Jiri Vachtenheim, Lubica Ondrušová
doaj   +1 more source

Bayesian model-based inference of transcription factor activity [PDF]

, 2007
<b>Background:</b> In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is considered to be an accurate surrogate for the true ...
Rogers, S, Girolami, M, Rogers, Simon, Girolami, Mark, Khanin, R, Khanin, Raya   +5 more
core   +1 more source

IL-2 delivery to CD8+ T cells during infection requires MRTF/SRF-dependent gene expression and cytoskeletal dynamics

Nature Communications
Paracrine IL-2 signalling drives the CD8 + T cell expansion and differentiation that allow protection against viral infections, but the underlying molecular events are incompletely understood.
Diane Maurice, Patrick Costello, Jessica Diring, Francesco Gualdrini, Bruno Frederico, Richard Treisman   +5 more
doaj   +1 more source

Transcription Factors Modulate c-Fos Transcriptional Bursts

Cell Reports, 2014
Transcription is a stochastic process occurring mostly in episodic bursts. Although the local chromatin environment is known to influence the bursting behavior on long timescales, the impact of transcription factors (TFs)—especially in rapidly inducible ...
Adrien Senecal, Brian Munsky, Florence Proux, Nathalie Ly, Floriane E. Braye, Christophe Zimmer, Florian Mueller, Xavier Darzacq   +7 more
doaj   +1 more source

Analysis of G-quadruplexes upstream of herpesvirus miRNAs: evidence of G-quadruplex mediated regulation of KSHV miR-K12–1-9,11 cluster and HCMV miR-US33

BMC Molecular and Cell Biology, 2020
Background G-quadruplexes regulate gene expression, recombination, packaging and latency in herpesviruses. Herpesvirus-encoded miRNAs have been linked to important biological functions. The presence and the biological role of G-quadruplexes have not been
Shivani Kumar, Divya Choudhary, Anupam Patra, Neel Sarovar Bhavesh, Perumal Vivekanandan   +4 more
doaj   +1 more source