Results 231 to 240 of about 2,206,258 (297)

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Metatranscriptomic-driven insights into mucosal glycan degradation by the human gut microbiota. [PDF]

FEMS Microbiol Ecol
Bauchinger F, Berry D.
europepmc   +1 more source

Transcriptional determinants of lipid mobilization in human adipocytes [PDF]

Alison C. Ludzki, Mattias Hansen, Danae Zareifi, Jutta Jalkanen, Zhiqiang Huang, Muhmmad Omar‐Hmeadi, Gianluca Renzi, Felix Klingelhuber, Sebastian Boland, Yohannes A. Ambaw, Na Wang, Anastasios Damdimopoulos, Jianping Liu, Tomas Jernberg, Paul Petrus, Peter Arner, Natalie Krahmer, Rongrong Fan, Eckardt Treuter, Hui Gao, Mikael Rydén, Niklas Mejhert   +21 more
openalex   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

<b>Molecular genetic characterization of</b> <b>CASEIN KINASE 1-LIKE 12</b> <b>in</b> <i><b>Arabidopsis</b></i>. [PDF]

Plant Signal Behav
Seluzicki A, Branks AE, Poosapati S, Chory J.   +3 more
europepmc   +1 more source

Transcriptional selectivity in early mouse embryos: a qualitative studu

, 1991
Claire Bonnerot, Muriel Vernet, G Grimber, Pascale Briand, Jean‐François Nicolas   +4 more
openalex   +2 more sources

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Transcriptional regulation of telomeric repeat-containing RNA by the G-quadruplex-binding Ewing sarcoma protein. [PDF]

Sci Rep
Ulum LL, Matsudaira W, Yamanashi M, Shibata N, Saha S, Ishihara A, Oyoshi T.   +6 more
europepmc   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source