Results 31 to 40 of about 15,248,084 (403)

Re-utilization of a transcription factor

open access: yeseLife, 2016
The temporal transcription factor Krüppel has a dual role in the development of neurons.
Filipe Pinto-Teixeira, Claude Desplan
doaj   +1 more source

SUMOylation of zebrafish transcription factor Zbtb21 affects its transcription activity [PDF]

open access: yesPeerJ
Background Post-translational modification by Small Ubiquitin-like MOdifier (SUMO) is an important mechanism to regulate protein activity, protein stability, and localization of substrates.
Zhou Fang   +3 more
doaj   +2 more sources

Structural fingerprints of transcription factor binding site regions [PDF]

open access: yes, 2009
Fourier transforms are a powerful tool in the prediction of DNA sequence properties, such as the presence/absence of codons. We have previously compiled a database of the structural properties of all 32,896 unique DNA octamers.
Christopher Hunter   +8 more
core   +2 more sources

Androgen Receptor Regulates Transcription of the ZEB1 Transcription Factor

open access: yesInternational Journal of Endocrinology, 2011
The zinc finger E-box binding protein 1 (ZEB1) transcription factor belongs to a two-member family of zinc-finger homeodomain proteins involved in physiological and pathological events mostly relating to cell migration and epithelial to mesenchymal ...
Bynthia M. Anose, Michel M. Sanders
doaj   +1 more source

The Sox2 transcription factor binds RNA

open access: yesNature Communications, 2020
Some transcription factors have been proposed to functionally interact with RNA to facilitate proper regulation of gene expression. Here the authors demonstrate that human Sox2 interact directly and with high affinity to RNAs through its HMG DNA-binding ...
Zachariah E. Holmes   +6 more
doaj   +1 more source

Human transcription factor protein interaction networks

open access: yesNature Communications, 2022
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here the authors identify 6703 and 1536 protein–protein interactions for 109 different human TFs through BioID and AP-MS analyses, respectively.
Helka Göös   +8 more
doaj   +1 more source

Transcriptional regulation of haematopoietic transcription factors [PDF]

open access: yesStem Cell Research & Therapy, 2011
The control of differential gene expression is central to all metazoan biology. Haematopoiesis represents one of the best understood developmental systems where multipotent blood stem cells give rise to a range of phenotypically distinct mature cell types, all characterised by their own distinctive gene expression profiles.
Berthold Göttgens   +3 more
openaire   +2 more sources

Transcription factor p73 regulates Th1 differentiation

open access: yesNature Communications, 2020
Heterogeneous helper T (Th) cell responses contribute to differential susceptibility to immunological disorders. Here the authors perform haplotype-based computational screens of 16 inbred mouse strains to identify a transcription factor, p73, as an ...
Min Ren   +11 more
doaj   +1 more source

Pleiotropic functions for transcription factor zscan10. [PDF]

open access: yesPLoS ONE, 2014
The transcription factor Zscan10 had been attributed a role as a pluripotency factor in embryonic stem cells based on its interaction with Oct4 and Sox2 in in vitro assays.
Petra Kraus   +35 more
doaj   +1 more source

Activating transcription factor 4-dependent hsa-miR-663a transcription mediates mTORC1/p70S6K1 signaling underleucine deprivation

open access: yesFrontiers in Nutrition, 2022
The mechanistic target of rapamycin complex 1 (mTORC1) is involved in nutrient-induced signaling and is a master regulator of cell growth and metabolism.
Junki Yamamura   +3 more
doaj   +1 more source

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