Results 31 to 40 of about 1,572,227 (290)

Androgen Receptor Regulates Transcription of the ZEB1 Transcription Factor

International Journal of Endocrinology, 2011
The zinc finger E-box binding protein 1 (ZEB1) transcription factor belongs to a two-member family of zinc-finger homeodomain proteins involved in physiological and pathological events mostly relating to cell migration and epithelial to mesenchymal ...
Bynthia M. Anose, Michel M. Sanders
doaj   +1 more source

Transcription Factor Binding to Replicated DNA

Cell Reports, 2020
Summary: Genome replication perturbs the DNA regulatory environment by displacing DNA-bound proteins, replacing nucleosomes, and introducing dosage imbalance between regions replicating at different S-phase stages.
Raz Bar-Ziv, Sagie Brodsky, Michal Chapal, Naama Barkai   +3 more
doaj   +1 more source

Activating transcription factor 4-dependent hsa-miR-663a transcription mediates mTORC1/p70S6K1 signaling underleucine deprivation

Frontiers in Nutrition, 2022
The mechanistic target of rapamycin complex 1 (mTORC1) is involved in nutrient-induced signaling and is a master regulator of cell growth and metabolism.
Junki Yamamura, Sihui Ma, Huijuan Jia, Hisanori Kato   +3 more
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NTH201, a Novel Class II KNOTTED1-Like Protein, Facilitates the Cell-to-Cell Movement of Tobacco mosaic virus in Tobacco

Molecular Plant-Microbe Interactions, 2008
NTH201, a novel class II KNOTTED1-like protein gene, was cloned from tobacco (Nicotiana tabacum cv. Xanthi) and its role in Tobacco mosaic virus (TMV) infection was analyzed. Virus-induced gene silencing of NTH201 caused a delay in viral RNA accumulation
Atsushi Yoshii, Takumi Shimizu, Akiko Yoshida, Koji Hamada, Keitaro Sakurai, Yasuyuki Yamaji, Masashi Suzuki, Shigetou Namba, Tadaaki Hibi   +8 more
doaj   +1 more source

Determinants of transcription factor regulatory range

Nature Communications, 2020
Characterization of the distance over which TF binding influences gene expression is important for inferring target genes. Here the authors study this relationship using thousands of genomic data sets, finding two classes of TFs with distinct ranges of ...
Chen-Hao Chen, Rongbin Zheng, Collin Tokheim, Xin Dong, Jingyu Fan, Changxin Wan, Qin Tang, Myles Brown, Jun S. Liu, Clifford A. Meyer, X. Shirley Liu   +10 more
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Transcription factor mutations in myelodysplastic/myeloproliferative neoplasms

Haematologica, 2010
Background Aberrant activation of tyrosine kinases, caused by either mutation or gene fusion, is of major importance for the development of many hematologic malignancies, particularly myeloproliferative neoplasms.
Thomas Ernst, Andrew Chase, Katerina Zoi, Katherine Waghorn, Claire Hidalgo-Curtis, Joannah Score, Amy Jones, Francis Grand, Andreas Reiter, Andreas Hochhaus, Nicholas C.P. Cross   +10 more
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Transcription factor dynamics

Microbiology, 2008
Gene expression is a fundamental process that is highly conserved from humans to bacteria. The first step in gene expression, transcription, is performed by structurally conserved DNA-dependent RNA polymerases (RNAPs), which results in the synthesis of an RNA molecule from a DNA template.
Lewis, P. J., Doherty, G. P., Clarke, J.
openaire   +4 more sources

A patient‐derived explant (PDE) model of hormone‐dependent cancer

Molecular Oncology, 2018
Breast and prostate cancer research to date has largely been predicated on the use of cell lines in vitro or in vivo. These limitations have led to the development of more clinically relevant models, such as organoids or murine xenografts that utilize ...
Margaret M. Centenera, Theresa E. Hickey, Shalini Jindal, Natalie K. Ryan, Preethi Ravindranathan, Hisham Mohammed, Jessica L. Robinson, Matthew J. Schiewer, Shihong Ma, Payal Kapur, Peter D. Sutherland, Clive E. Hoffmann, Claus G. Roehrborn, Leonard G. Gomella, Jason S. Carroll, Stephen N. Birrell, Karen E. Knudsen, Ganesh V. Raj, Lisa M. Butler, Wayne D. Tilley   +19 more
doaj   +1 more source

Transcription Factor Networks in Drosophila melanogaster

Cell Reports, 2014
Specific cellular fates and functions depend on differential gene expression, which occurs primarily at the transcriptional level and is controlled by complex regulatory networks of transcription factors (TFs).
David Y. Rhee, Dong-Yeon Cho, Bo Zhai, Matthew Slattery, Lijia Ma, Julian Mintseris, Christina Y. Wong, Kevin P. White, Susan E. Celniker, Teresa M. Przytycka, Steven P. Gygi, Robert A. Obar, Spyros Artavanis-Tsakonas   +12 more
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The Sox2 transcription factor binds RNA

Nature Communications, 2020
Some transcription factors have been proposed to functionally interact with RNA to facilitate proper regulation of gene expression. Here the authors demonstrate that human Sox2 interact directly and with high affinity to RNAs through its HMG DNA-binding ...
Zachariah E. Holmes, Desmond J. Hamilton, Taeyoung Hwang, Nicholas V. Parsonnet, John L. Rinn, Deborah S. Wuttke, Robert T. Batey   +6 more
doaj   +1 more source