Results 31 to 40 of about 2,419,657 (375)
SUMOylation of zebrafish transcription factor Zbtb21 affects its transcription activity [PDF]
PeerJBackground Post-translational modification by Small Ubiquitin-like MOdifier (SUMO) is an important mechanism to regulate protein activity, protein stability, and localization of substrates.
Zhou Fang +3 more
doaj +2 more sources
Pleiotropic functions for transcription factor zscan10. [PDF]
PLoS ONE, 2014 The transcription factor Zscan10 had been attributed a role as a pluripotency factor in embryonic stem cells based on its interaction with Oct4 and Sox2 in in vitro assays.
Petra Kraus +35 more
doaj +1 more source
Androgen Receptor Regulates Transcription of the ZEB1 Transcription Factor
International Journal of Endocrinology, 2011 The zinc finger E-box binding protein 1 (ZEB1) transcription factor belongs to a two-member family of zinc-finger homeodomain proteins involved in physiological and pathological events mostly relating to cell migration and epithelial to mesenchymal ...
Bynthia M. Anose, Michel M. Sanders
doaj +1 more source
Transcription factor p73 regulates Th1 differentiation
Nature Communications, 2020 Heterogeneous helper T (Th) cell responses contribute to differential susceptibility to immunological disorders. Here the authors perform haplotype-based computational screens of 16 inbred mouse strains to identify a transcription factor, p73, as an ...
Min Ren +11 more
doaj +1 more source
Functional Characteristics of Gene Expression Motifs with Single and Dual Strategies of Regulation [PDF]
Biomed. Phys. Eng. Express, 2 , 025009(2016), 2016 Transcriptional regulation by transcription factors and post-transcriptional regulation by microRNAs constitute two major modes of regulation of gene expression. While gene expression motifs incorporating solely transcriptional regulation are well investigated, the dynamics of motifs with dual strategies of regulation, i.e., both transcriptional and ...
arxiv +1 more source
Transcriptional regulation of haematopoietic transcription factors [PDF]
Stem Cell Research & Therapy, 2011 The control of differential gene expression is central to all metazoan biology. Haematopoiesis represents one of the best understood developmental systems where multipotent blood stem cells give rise to a range of phenotypically distinct mature cell types, all characterised by their own distinctive gene expression profiles.
Berthold Göttgens +3 more
openaire +2 more sources
The Sox2 transcription factor binds RNA
Nature Communications, 2020 Some transcription factors have been proposed to functionally interact with RNA to facilitate proper regulation of gene expression. Here the authors demonstrate that human Sox2 interact directly and with high affinity to RNAs through its HMG DNA-binding ...
Zachariah E. Holmes +6 more
doaj +1 more source
Frontiers in Nutrition, 2022 The mechanistic target of rapamycin complex 1 (mTORC1) is involved in nutrient-induced signaling and is a master regulator of cell growth and metabolism.
Junki Yamamura +3 more
doaj +1 more source
Microbiology, 2008 Gene expression is a fundamental process that is highly conserved from humans to bacteria. The first step in gene expression, transcription, is performed by structurally conserved DNA-dependent RNA polymerases (RNAPs), which results in the synthesis of an RNA molecule from a DNA template.
Lewis, P. J., Doherty, G. P., Clarke, J.
openaire +5 more sources
Molecular Plant-Microbe Interactions, 2008 NTH201, a novel class II KNOTTED1-like protein gene, was cloned from tobacco (Nicotiana tabacum cv. Xanthi) and its role in Tobacco mosaic virus (TMV) infection was analyzed. Virus-induced gene silencing of NTH201 caused a delay in viral RNA accumulation
Atsushi Yoshii +8 more
doaj +1 more source