Results 31 to 40 of about 15,248,084 (403)
Re-utilization of a transcription factor
The temporal transcription factor Krüppel has a dual role in the development of neurons.
Filipe Pinto-Teixeira, Claude Desplan
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SUMOylation of zebrafish transcription factor Zbtb21 affects its transcription activity [PDF]
Background Post-translational modification by Small Ubiquitin-like MOdifier (SUMO) is an important mechanism to regulate protein activity, protein stability, and localization of substrates.
Zhou Fang+3 more
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Structural fingerprints of transcription factor binding site regions [PDF]
Fourier transforms are a powerful tool in the prediction of DNA sequence properties, such as the presence/absence of codons. We have previously compiled a database of the structural properties of all 32,896 unique DNA octamers.
Christopher Hunter+8 more
core +2 more sources
Androgen Receptor Regulates Transcription of the ZEB1 Transcription Factor
The zinc finger E-box binding protein 1 (ZEB1) transcription factor belongs to a two-member family of zinc-finger homeodomain proteins involved in physiological and pathological events mostly relating to cell migration and epithelial to mesenchymal ...
Bynthia M. Anose, Michel M. Sanders
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The Sox2 transcription factor binds RNA
Some transcription factors have been proposed to functionally interact with RNA to facilitate proper regulation of gene expression. Here the authors demonstrate that human Sox2 interact directly and with high affinity to RNAs through its HMG DNA-binding ...
Zachariah E. Holmes+6 more
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Human transcription factor protein interaction networks
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here the authors identify 6703 and 1536 protein–protein interactions for 109 different human TFs through BioID and AP-MS analyses, respectively.
Helka Göös+8 more
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Transcriptional regulation of haematopoietic transcription factors [PDF]
The control of differential gene expression is central to all metazoan biology. Haematopoiesis represents one of the best understood developmental systems where multipotent blood stem cells give rise to a range of phenotypically distinct mature cell types, all characterised by their own distinctive gene expression profiles.
Berthold Göttgens+3 more
openaire +2 more sources
Transcription factor p73 regulates Th1 differentiation
Heterogeneous helper T (Th) cell responses contribute to differential susceptibility to immunological disorders. Here the authors perform haplotype-based computational screens of 16 inbred mouse strains to identify a transcription factor, p73, as an ...
Min Ren+11 more
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Pleiotropic functions for transcription factor zscan10. [PDF]
The transcription factor Zscan10 had been attributed a role as a pluripotency factor in embryonic stem cells based on its interaction with Oct4 and Sox2 in in vitro assays.
Petra Kraus+35 more
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The mechanistic target of rapamycin complex 1 (mTORC1) is involved in nutrient-induced signaling and is a master regulator of cell growth and metabolism.
Junki Yamamura+3 more
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