Results 91 to 100 of about 5,388 (199)

Impacting elementary STEM teacher leadership identities

School Science and Mathematics, Volume 125, Issue 5, Page 519-531, October 2025.
Abstract Learning science, technology, engineering, and mathematics (STEM) subjects starting at a young age helps prepare students for a variety of careers both inside and outside of the sciences. Yet, addressing integrated STEM in an elementary school setting can be challenging. Teacher leadership is one way to address this challenge.
Kelsey Quaisley, Rachel Funk, Leilani Pai, Sally Ahrens, Wendy M. Smith, Amanda Thomas   +5 more
wiley   +1 more source

Zinc antagonizes cadmium-induced osteoporosis in mice by inhibiting Cd2+ deposition, enhancing antioxidant capacity and correcting bone metabolic disorders

Ecotoxicology and Environmental Safety
Chronic cadmium (Cd) exposure is a recognized risk factor for osteoporosis. Zinc (Zn) plays crucial roles in bone metabolism, yet intervention roles of Zn2+ against Cd-induced osteoporosis are incompletely understood.
Yingze Qin, Lisha Fan, Yi Feng, Ding Zhang, Chuan Xiang   +4 more
doaj   +1 more source

Zinc-induced Dnmt1 expression involves antagonism between MTF-1 and nuclear receptor SHP [PDF]

, 2011
Dnmt1 is frequently overexpressed in cancers, which contributes significantly to cancer-associated epigenetic silencing of tumor suppressor genes. However, the mechanism of Dnmt1 overexpression remains elusive.
Andrews, Avila, Chan, Chung, Di Croce, G. K. Andrews, Green, HAROON, He, Huang, Huang, Jinawath, Kerr, Kimura, Kishikawa, L. Wang, Laurent-Puig, Lee, McCabe, Ostrakhovitch, Park, Park, Park, Robert, Rountree, Seeff, Shi, Shukla, Song, Song, Takamura, Tamura, Vire, Wang, Wang, WANG, Wang, Williams, Y. Zhang, Zhang, Zhang   +40 more
core   +2 more sources

Emerging Roles of Metallothioneins in Human Pathophysiology: A Review

Health Science Reports, Volume 8, Issue 9, September 2025.
ABSTRACT Background Metallothioneins (MTs) are small molecular‐weight proteins that either bind or release essential transition metals, depending on a specific cell situation. There are 4 major isoforms of MTs (1–4), of which MT1/2 is found in every cell in the body.
Ousman Mohammed, Abdisa Tufa, Solomon Tebeje Gizaw   +2 more
wiley   +1 more source

Eukaryotic initiation factor 5A dephosphorylation is required for translational arrest in stationary phase cells [PDF]

, 2013
The protein known as eIF5A (eukaryotic initiation factor 5A) has an elusive role in translation. It has a unique and essential hypusine modification at a conserved lysine residue in most eukaryotes.
Castilho, Beatriz A., Chung, Janete, Rocha, Antonio A., Schenkman, Sergio, Tonelli, Renata R.   +4 more
core   +1 more source

Beyond the Binary: Controlling Natural Sex‐Change in Hermaphroditic Fishes

Reviews in Aquaculture, Volume 17, Issue 4, September 2025.
ABSTRACT Sex‐change in hermaphroditic fishes is a complex but natural biological phenomenon that has significant implications for aquaculture fingerling production, selective breeding, and grow‐out. Understanding the physiological, endocrinological, and molecular pathways underlying hermaphroditism in fishes offers unique opportunities to manipulate ...
Roni Chandra Mondal, Jarrod L. Guppy, Maria A. Villacis‐Escobar, Dean R. Jerry   +3 more
wiley   +1 more source

Characterization of MtnE, the fifth metallothionein member in Drosophila [PDF]

, 2018
Metallothioneins (MTs) constitute a family of cysteine-rich, low molecular weight metal-binding proteins which occur in almost all forms of life. They bind physiological metals, such as zinc and copper, as well as nonessential, toxic heavy metals, such ...
Atanesyan, Lilit, Celniker, Susan, Georgiev, Oleg, Günther, Viola, Schaffner, Walter   +4 more
core  

An allelic variant in the intergenic region between ERAP1 and ERAP2 correlates with an inverse expression of the two genes [PDF]

, 2018
The Endoplasmatic Reticulum Aminopeptidases ERAP1 and ERAP2 are implicated in a variety of immune and non-immune functions. Most studies however have focused on their role in shaping the HLA class I peptidome by trimming peptides to the optimal size ...
Cauli, A, Fiorillo, Mt, Mathieu, A, Paladini, F, Piga, M, Sorrentino, R, Tedeschi, V, Vitulano, C   +7 more
core   +2 more sources

Exosomes, autophagy, and cancer: A complex triad

International Journal of Cancer, Volume 157, Issue 3, Page 405-415, 1 August 2025.
Abstract Cancer remains one of the leading causes of death worldwide. Despite remarkable progress in prevention, diagnosis, and therapy, the incidence of certain types of cancer persists, urging the identification of clinically relevant biomarkers and the development of novel therapeutic strategies to improve clinical outcomes and overcome treatment ...
María Guerra‐Andrés, Álvaro F. Fernández, Tania Fontanil   +2 more
wiley   +1 more source

A cross‐sectional study evaluating the frequency of HIV drug resistance mutations among individuals diagnosed with HIV‐1 in tenofovir disoproxil fumarate‐based pre‐exposure prophylaxis rollout programmes in Kenya, Zimbabwe, Eswatini and South Africa

Journal of the International AIDS Society, Volume 28, Issue 8, August 2025.
Abstract Introduction The ongoing rollout of oral tenofovir‐based pre‐exposure prophylaxis (PrEP) has the potential to reduce HIV‐1 incidence, but HIV drug resistance (HIVDR) in individuals who acquire HIV‐1 on PrEP could threaten the treatment effectiveness of overlapping antiretrovirals (tenofovir/emtricitabine), contribute to development of ...
Urvi M. Parikh, Lauren D. Kudrick, Lisa Levy, Everline Bosek, Bhavna H. Chohan, Irene Mukui, Sarah Masyuko, Nonhlanhla Ndlovu, Imelda Mahaka, Owen Mugurungi, Gertrude Ncube, Anita Hettema, Sindy N. Matse, Saiqa Mullick, Carole L. Wallis, Amy L. Heaps, Kerri J. Penrose, Kevin D. McCormick, Lubbe Wiesner, Peter L. Anderson, Jill M. Peterson, Connie Celum, Barbra A. Richardson, Delivette Castor, Shannon Allen, Kristine Torjesen, John W. Mellors, Global Evaluation of Microbicide Sensitivity (GEMS) Project   +27 more
wiley   +1 more source