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Transcription Factors in Biocontrol Fungi [PDF]

open access: yesJournal of Fungi
Transcription factors are extensively found in fungi and are involved in the regulation of multiple biological processes, including growth, development, conidiation, morphology, stresses tolerance, and virulence, as well as the production of secondary ...
Han-Jian Song   +4 more
doaj   +2 more sources

Targeting Transcription Factors for Cancer Treatment

open access: yesMolecules, 2018
Transcription factors are involved in a large number of human diseases such as cancers for which they account for about 20% of all oncogenes identified so far. For long time, with the exception of ligand-inducible nuclear receptors, transcription factors
Mélanie Lambert   +3 more
doaj   +2 more sources

Triple-negative and triple-positive breast cancer cells reciprocally control their growth and migration via the S100A4 pathway

open access: yesCell Adhesion & Migration, 2022
The study’s aim was to investigate the S100A4-mediated mechanisms of the regulation of tumor cell proliferation and migration in the human triple-positive breast carcinoma cell line MCF-7 (TPBC) and triple-negative breast carcinoma cell line MDA-MB-231 ...
Elena A. Dukhanina   +3 more
doaj   +1 more source

Multiple Functions of MYB Transcription Factors in Abiotic Stress Responses

open access: yesInternational Journal of Molecular Sciences, 2021
Plants face a more volatile environment than other organisms because of their immobility, and they have developed highly efficient mechanisms to adapt to stress conditions.
Xiaopei Wang, Ya Niu, Yuan Zheng
semanticscholar   +1 more source

A novel chromatin-remodeling complex variant, dcPBAF, is involved in maintaining transcription in differentiated neurons

open access: yesFrontiers in Cell and Developmental Biology, 2023
The Polybromo-associated BAF (BRG1- or BRM-associated factors) (PBAF) chromatin-remodeling complex is essential for transcription in mammalian cells.
Nataliya V. Soshnikova   +12 more
doaj   +1 more source

Primate-specific stress-induced transcription factor POU2F1Z protects human neuronal cells from stress

open access: yesScientific Reports, 2021
The emergence of new primate-specific genes is an essential factor in human and primate brain development and functioning. POU2F1/Oct-1 is a transcription regulator in higher eukaryotes which is involved in the regulation of development, differentiation,
Alexander G. Stepchenko   +6 more
doaj   +1 more source

Optimization of Cdx Transcription Factors Characteristics

open access: yesЖурнал інженерних наук, 2023
This study presents a new application of TOPSIS for the optimization of transcription factors characteristics. This application is essential as it can help compare the characteristics of these proteins and determine the optimized output of their ...
Javanbakht T.
doaj   +1 more source

Insulin-Responsive Transcription Factors

open access: yesBiomolecules, 2021
The hormone insulin executes its function via binding and activating of the insulin receptor, a receptor tyrosine kinase that is mainly expressed in skeletal muscle, adipocytes, liver, pancreatic β-cells, and in some areas of the central nervous system ...
Gerald Thiel   +2 more
doaj   +1 more source

Transcription factors organize into functional groups on the linear genome and in 3D chromatin

open access: yesHeliyon, 2023
Transcription factors (TFs) and their binding sites have evolved to interact cooperatively or competitively with each other. Here we examine in detail, across multiple cell lines, such cooperation or competition among TFs both in sequential and spatial ...
Rakesh Netha Vadnala   +3 more
doaj   +1 more source

Transcription factors in microcephaly

open access: yesFrontiers in Neuroscience, 2023
Higher cognition in humans, compared to other primates, is often attributed to an increased brain size, especially forebrain cortical surface area. Brain size is determined through highly orchestrated developmental processes, including neural stem cell ...
Youngshin Lim, Youngshin Lim
doaj   +1 more source

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