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The Human Transcription Factors [PDF]

open access: yesCell, 2018
Transcription factors (TFs) recognize specific DNA sequences to control chromatin and transcription, forming a complex system that guides expression of the genome. Despite keen interest in understanding how TFs control gene expression, it remains challenging to determine how the precise genomic binding sites of TFs are specified and how TF binding ...
Samuel A. Lambert   +9 more
semanticscholar   +7 more sources

Transcription factors in microcephaly

open access: yesFrontiers in Neuroscience, 2023
Higher cognition in humans, compared to other primates, is often attributed to an increased brain size, especially forebrain cortical surface area. Brain size is determined through highly orchestrated developmental processes, including neural stem cell ...
Youngshin Lim, Youngshin Lim
doaj   +3 more sources

Transcription Factors in Biocontrol Fungi [PDF]

open access: yesJournal of Fungi
Transcription factors are extensively found in fungi and are involved in the regulation of multiple biological processes, including growth, development, conidiation, morphology, stresses tolerance, and virulence, as well as the production of secondary ...
Han-Jian Song   +4 more
doaj   +2 more sources

Smad transcription factors. [PDF]

open access: yesGenes & Development, 2005
Smad transcription factors lie at the core of one of the most versatile cytokine signaling pathways in metazoan biology-the transforming growth factor-beta (TGFbeta) pathway.
J. Massagué, J. Seoane, D. Wotton
semanticscholar   +3 more sources

Triple-negative and triple-positive breast cancer cells reciprocally control their growth and migration via the S100A4 pathway

open access: yesCell Adhesion & Migration, 2022
The study’s aim was to investigate the S100A4-mediated mechanisms of the regulation of tumor cell proliferation and migration in the human triple-positive breast carcinoma cell line MCF-7 (TPBC) and triple-negative breast carcinoma cell line MDA-MB-231 ...
Elena A. Dukhanina   +3 more
doaj   +1 more source

Multiple Functions of MYB Transcription Factors in Abiotic Stress Responses

open access: yesInternational Journal of Molecular Sciences, 2021
Plants face a more volatile environment than other organisms because of their immobility, and they have developed highly efficient mechanisms to adapt to stress conditions.
Xiaopei Wang, Ya Niu, Yuan Zheng
semanticscholar   +1 more source

A novel chromatin-remodeling complex variant, dcPBAF, is involved in maintaining transcription in differentiated neurons

open access: yesFrontiers in Cell and Developmental Biology, 2023
The Polybromo-associated BAF (BRG1- or BRM-associated factors) (PBAF) chromatin-remodeling complex is essential for transcription in mammalian cells.
Nataliya V. Soshnikova   +12 more
doaj   +1 more source

The Transcription Factor Encyclopedia [PDF]

open access: yesGenome Biology, 2012
AbstractHere we present the Transcription Factor Encyclopedia (TFe), a new web-based compendium of mini review articles on transcription factors (TFs) that is founded on the principles of open access and collaboration. Our consortium of over 100 researchers has collectively contributed over 130 mini review articles on pertinent human, mouse and rat TFs.
Yusuf, Dimas   +114 more
openaire   +14 more sources

Primate-specific stress-induced transcription factor POU2F1Z protects human neuronal cells from stress

open access: yesScientific Reports, 2021
The emergence of new primate-specific genes is an essential factor in human and primate brain development and functioning. POU2F1/Oct-1 is a transcription regulator in higher eukaryotes which is involved in the regulation of development, differentiation,
Alexander G. Stepchenko   +6 more
doaj   +1 more source

Eukaryotic transcription factors [PDF]

open access: yesBiochemical Journal, 1990
AbstractMany nuclear proteins have been found recently to interact with short conserved sequences which are involved in regulating the transcription of various genes. Nuclear transcription factors may be arbitrarily subdivided into two groups, ubiquitous and tissue‐specific.
Alexander G. Stepchenko   +1 more
openaire   +5 more sources

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