Results 21 to 30 of about 14,263,333 (360)

Immunoexpression of stem cell markers SOX-2, NANOG AND OCT4 in ameloblastoma [PDF]

open access: yesPeerJ, 2023
Background Ameloblastoma (AME) is characterized by a locally invasive growth pattern. In an attempt to justify the aggressiveness of neoplasms, the investigation of the role of stem cells has gained prominence.
Karolyny Martins Balbinot   +10 more
doaj   +2 more sources

Different Putative Methyltransferases Have Different Effects on the Expression Patterns of Cellulolytic Genes

open access: yesJournal of Fungi, 2023
Putative methyltranferase LaeA and LaeA-like proteins, conserved in many filamentous fungi, regulate fungal growth, development, virulence, the biosynthesis of secondary metabolites, and the production of cellulolytic enzymes.
Zhongjiao Liu   +4 more
doaj   +1 more source

Different functions of PHF10 isoforms – subunits of the PBAF chromatin remodeling complex

open access: yesВавиловский журнал генетики и селекции, 2019
Chromatin remodelling multiprotein complexes play an important role in regulation of gene expression in embryogenesis and in the adult organism. Mutations in the subunits of the complexes are often lethal or lead to developmental defects.
A. A. Sheynov   +4 more
doaj   +1 more source

Pioneer Transcription Factors Initiating Gene Network Changes.

open access: yesAnnual Review of Genetics, 2020
Pioneer transcription factors have the intrinsic biochemical ability to scan partial DNA sequence motifs that are exposed on the surface of a nucleosome and thus access silent genes that are inaccessible to other transcription factors.
K. Zaret
semanticscholar   +1 more source

Transcription Factor Dynamics [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2021
To predict transcription, one needs a mechanistic understanding of how the numerous required transcription factors (TFs) explore the nuclear space to find their target genes, assemble, cooperate, and compete with one another. Advances in fluorescence microscopy have made it possible to visualize real-time TF dynamics in living cells, leading to two ...
Feiyue Lu, Timothée Lionnet
openaire   +2 more sources

Synthetic reconstruction of the hunchback promoter specifies the role of Bicoid, Zelda and Hunchback in the dynamics of its transcription

open access: yeseLife, 2022
For over 40 years, the Bicoid-hunchback (Bcd-hb) system in the fruit fly embryo has been used as a model to study how positional information in morphogen concentration gradients is robustly translated into step-like responses.
Gonçalo Fernandes   +8 more
doaj   +1 more source

Evolution of Developmental GATA Factors in Nematodes

open access: yesJournal of Developmental Biology, 2020
GATA transcription factors are found in animals, plants, and fungi. In animals, they have important developmental roles in controlling specification of cell identities and executing tissue-specific differentiation.
Ethan Eurmsirilerd, Morris F. Maduro
doaj   +1 more source

The databases of transcription factors [PDF]

open access: yesHereditas (Beijing), 2011
The control of gene transcription is a critical level of gene expression regulation. The interactions between transcription factors (TF) and their DNA binding sites (TFBS) play a key role at this level. In order to decipher the molecular mechanism of the interactions of TFs with TFBSs and construct transcription regulatory network, it is necessary to ...
Jin-Ke Wang, Hong-Fei Chen
openaire   +3 more sources

Transcription Factors in Alkaloid Engineering

open access: yesBiomolecules, 2021
Plants produce a large variety of low-molecular-weight and specialized secondary compounds. Among them, nitrogen-containing alkaloids are the most biologically active and are often used in the pharmaceutical industry. Although alkaloid chemistry has been
Yasuyuki Yamada, Fumihiko Sato
doaj   +1 more source

Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP

open access: yesScientific Reports, 2017
The PBAF chromatin-remodeling complexes are multi-protein machines, regulating expression of genes involved in proliferation and differentiation. PHF10 is a subunit of the PBAF essential for its association with chromatin. Mammalian PHF10 is expressed as
Victor V. Tatarskiy   +5 more
doaj   +1 more source

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