Results 31 to 40 of about 2,388,983 (379)

Cis-regulatory module detection using constraint programming [PDF]

open access: yes, 2010
We propose a method for finding CRMs in a set of co-regulated genes. Each CRM consists of a set of binding sites of transcription factors. We wish to find CRMs involving the same transcription factors in multiple sequences.
Guns, Tias   +3 more
core   +1 more source

Radial or bilateral? The molecular basis of floral symmetry. [PDF]

open access: yes, 2020
In the plant kingdom, the flower is one of the most relevant evolutionary novelties. Floral symmetry has evolved multiple times from the ancestral condition of radial to bilateral symmetry.
ACETO, SERENA   +2 more
core   +1 more source

Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP

open access: yesScientific Reports, 2017
The PBAF chromatin-remodeling complexes are multi-protein machines, regulating expression of genes involved in proliferation and differentiation. PHF10 is a subunit of the PBAF essential for its association with chromatin. Mammalian PHF10 is expressed as
Victor V. Tatarskiy   +5 more
doaj   +1 more source

Transcription factors underlying photoreceptor diversity

open access: yeseLife, 2023
During development, retinal progenitors navigate a complex landscape of fate decisions to generate the major cell classes necessary for proper vision. Transcriptional regulation is critical to generate diversity within these major cell classes.
Juan M Angueyra   +5 more
doaj   +1 more source

Transcriptional regulation of haematopoietic transcription factors [PDF]

open access: yesStem Cell Research & Therapy, 2011
The control of differential gene expression is central to all metazoan biology. Haematopoiesis represents one of the best understood developmental systems where multipotent blood stem cells give rise to a range of phenotypically distinct mature cell types, all characterised by their own distinctive gene expression profiles.
Berthold Göttgens   +3 more
openaire   +2 more sources

Multiple mechanisms of growth hormone-regulated gene transcription [PDF]

open access: yes, 2007
Diverse physiological actions of growth hormone (GH) are mediated by changes in gene transcription. Transcription can be regulated at several levels, including post-translational modification of transcription factors, and formation of multiprotein ...
Calinescu, Anda Alexandra   +8 more
core   +1 more source

Hypoxia-Inducible Factor-1α (HIF-1α) Potentiates β-Cell Survival after Islet Transplantation of Human and Mouse Islets

open access: yesCell Transplantation, 2013
A high proportion of β-cells die within days of islet transplantation. Reports suggest that induction of hypoxia-inducible factor-1α (HIF-1α) predicts adverse transplant outcomes.
Rebecca A. Stokes   +12 more
doaj   +1 more source

Functional Characteristics of Gene Expression Motifs with Single and Dual Strategies of Regulation [PDF]

open access: yesBiomed. Phys. Eng. Express, 2 , 025009(2016), 2016
Transcriptional regulation by transcription factors and post-transcriptional regulation by microRNAs constitute two major modes of regulation of gene expression. While gene expression motifs incorporating solely transcriptional regulation are well investigated, the dynamics of motifs with dual strategies of regulation, i.e., both transcriptional and ...
arxiv   +1 more source

Transcriptional Regulation: a Genomic Overview [PDF]

open access: yes, 2002
The availability of the Arabidopsis thaliana genome sequence allows a comprehensive analysis of transcriptional regulation in plants using novel genomic approaches and methodologies. Such a genomic view of transcription first necessitates the compilation
Riechmann, José Luis
core   +2 more sources

Predicting Combinatorial Binding of Transcription Factors to Regulatory Elements in the Human Genome by Association Rule Mining [PDF]

open access: yes, 2007
Cis-acting transcriptional regulatory elements in mammalian genomes typically contain specific combinations of binding sites for various transcription factors. Although some cisregulatory elements have been well studied, the combinations of transcription
Iyer, Vishwanath R.   +3 more
core   +2 more sources

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