Results 61 to 70 of about 15,365,257 (385)

An RxLR effector from phytophthora infestans prevents re-localisation of two plant NAC transcription factors from the endoplasmic reticulum to the nucleus [PDF]

open access: yes, 2013
The plant immune system is activated following the perception of exposed, essential and invariant microbial molecules that are recognised as non-self. A major component of plant immunity is the transcriptional induction of genes involved in a wide array ...
A Block   +70 more
core   +4 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Distinct transcriptomic features are associated with transitional and mature B-cell populations in the mouse spleen

open access: yesFrontiers in Immunology, 2015
Splenic transitional B-cells (T1 and T2) are selected to avoid self-reactivity and to safeguard against autoimmunity, then differentiate into mature follicular (FO-I and FO-II) and marginal zone (MZ) subsets.
Eden eKleiman   +14 more
doaj   +1 more source

Transcription factors in fungi [PDF]

open access: yesFEMS Microbiology Letters, 2008
Transcription factors (TFs) orchestrate gene expression control of a cell and, in many respects, their repertoire determines the life and functionality of the cell. For a better understanding of their regulatory mechanisms, it is essential to know the entire repertoire of TFs of a species.
openaire   +3 more sources

The T-cell oncogene Tal2 is a Target of PU.1 and upregulated during osteoclastogenesis [PDF]

open access: yes, 2013
Transcription factors play a crucial role in regulating differentiation processes during human life and are important in disease. The basic helix-loop-helix transcription factors Tal1 and Lyl1 play a major role in the regulation of gene expression in the
Courtial, Nadine   +5 more
core   +2 more sources

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

The interplay between chromatin and transcription factor networks during B cell development: who pulls the trigger first?

open access: yesFrontiers in Immunology, 2014
All mature blood cells derive from hematopoietic stem cells (HSCs) through gradual restriction of their cell fate potential and acquisition of specialized functions.
Mohamed-Amin eChoukrallah   +1 more
doaj   +1 more source

Zygotic pioneer factor activity of Odd-paired/Zic is necessary for late function of the Drosophila segmentation network

open access: yeseLife, 2020
Because chromatin determines whether information encoded in DNA is accessible to transcription factors, dynamic chromatin states in development may constrain how gene regulatory networks impart embryonic pattern.
Isabella V Soluri   +4 more
doaj   +1 more source

AnimalTFDB 3.0: a comprehensive resource for annotation and prediction of animal transcription factors

open access: yesNucleic Acids Res., 2018
The Animal Transcription Factor DataBase (AnimalTFDB) is a resource aimed to provide the most comprehensive and accurate information for animal transcription factors (TFs) and cofactors.
Hui Hu   +5 more
semanticscholar   +1 more source

Dynamic multifactor hubs interact transiently with sites of active transcription in Drosophila embryos. [PDF]

open access: yes, 2018
The regulation of transcription requires the coordination of numerous activities on DNA, yet how transcription factors mediate these activities remains poorly understood.
Darzacq, Xavier   +6 more
core   +1 more source

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