Results 81 to 90 of about 15,143,293 (401)
Regulation of TEAD Transcription Factors in Cancer Biology
Cells, 2019 Transcriptional enhanced associate domain (TEAD) transcription factors play important roles during development, cell proliferation, regeneration, and tissue homeostasis.
Hyunbin D. Huh +3 more
semanticscholar +1 more source
Walking, hopping and jumping: a model of transcription factor dynamics on DNA [PDF]
, 2011 We present a model of how transcription factors scan DNA to find their specific binding sites. Following the classical work of Winter et al. (1981), our model assumes two modes of transcription factor dynamics.
Barnes, David J., Chu, Dominique
core
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Transcription factors in megakaryocytes and platelets
Frontiers in Immunology, 2023 Transcription factors bind promoter or regulatory sequences of a gene to regulate its rate of transcription. However, they are also detected in anucleated platelets.
Hengjie Yuan +7 more
doaj +1 more source
In Vitro Analysis of the Thyroid Hormone Receptor in Mitochondrial Transcription [PDF]
, 2017 The central dogma theory relates how DNA is transcribed into messenger RNA (mRNAs) and then translated into proteins. Since the nucleus contains the majority of the DNA in cells, research related to transcription and translation focuses on these ...
Bestwick, Megan +3 more
core +1 more source
Quantifying mRNA synthesis and decay rates using small RNAs [PDF]
, 2009 Regulation of mRNA decay is a critical component of global cellular adaptation to changing environments. The corresponding changes in mRNA lifetimes can be coordinated with changes in mRNA transcription rates to fine-tune gene expression.
Bernstein +21 more
core +3 more sources
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
WRKY transcription factors in plant responses to stresses.
Journal of Integrative Plant Biology, 2017 The WRKY gene family is among the largest families of transcription factors (TFs) in higher plants. By regulating the plant hormone signal transduction pathway, these TFs play critical roles in some plant processes in response to biotic and abiotic ...
Jingjing Jiang +5 more
semanticscholar +1 more source
Effect of natural genetic variation on enhancer selection and function. [PDF]
, 2013 The mechanisms by which genetic variation affects transcription regulation and phenotypes at the nucleotide level are incompletely understood. Here we use natural genetic variation as an in vivo mutagenesis screen to assess the genome-wide effects of ...
Allison, KA +6 more
core
Predicting gene expression in the human malaria parasite Plasmodium falciparum using histone modification, nucleosome positioning, and 3D localization features. [PDF]
, 2019 Empirical evidence suggests that the malaria parasite Plasmodium falciparum employs a broad range of mechanisms to regulate gene transcription throughout the organism's complex life cycle.
Cook, Kate +4 more
core +2 more sources