Results 11 to 20 of about 5,538,535 (384)

Regulation of HPV transcription

open access: yesClinics, 2018
Human papillomavirus infection is associated with the development of malignant and benign neoplasms. Approximately 40 viral types can infect the anogenital mucosa and are categorized into high- and low-risk oncogenic human papillomavirus, depending on ...
Aline Lopes Ribeiro   +2 more
doaj   +4 more sources

Optogenetic regulation of transcription [PDF]

open access: yesBMC Neuroscience, 2018
Optogenetics has become widely recognized for its success in real-time control of brain neurons by utilizing non-mammalian photosensitive proteins to open or close membrane channels.
Oksana Polesskaya   +12 more
doaj   +4 more sources

Regulation of HSV Transcription

open access: bronzeJournal of Investigative Dermatology, 1984
Herpes simplex virus (HSV) transcripts share many features with both cellular mRNA and the mRNAs expressed by other nuclear-replicating DNA viruses: they are capped, polyadenylated, and generally have an approximately 150 base leader between the cap and translation initiation codon.
Edward K. Wagner
openalex   +4 more sources

Transcriptional Regulation of Inflammasomes [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Inflammasomes are multimolecular complexes with potent inflammatory activity. As such, their activity is tightly regulated at the transcriptional and post-transcriptional levels. In this review, we present the transcriptional regulation of inflammasome genes from sensors (e.g NLRP3) to substrates (e.g. IL-1β). Lineage-determining transcription
Cornut, Maxence   +2 more
openaire   +4 more sources

Transcriptional regulation [PDF]

open access: yesWormBook, 2005
The regulation of transcription in C. elegans shares many similarities to transcription in other organisms. The details of how specific transcription factors bind to target promoters and act as either activators or repressors are still being examined in many cases, but an increasing number of factors and their binding sites are being characterized ...
Peter G, Okkema, Michael, Krause
openaire   +2 more sources

Evolution of Regulated Transcription [PDF]

open access: yesCells, 2020
The genomes of all organisms abound with various cis-regulatory elements, which control gene activity. Transcriptional enhancers are a key group of such elements in eukaryotes and are DNA regions that form physical contacts with gene promoters and precisely orchestrate gene expression programs.
Oleg V. Bylino   +2 more
openaire   +4 more sources

The T-cell oncogene Tal2 is a Target of PU.1 and upregulated during osteoclastogenesis [PDF]

open access: yes, 2013
Transcription factors play a crucial role in regulating differentiation processes during human life and are important in disease. The basic helix-loop-helix transcription factors Tal1 and Lyl1 play a major role in the regulation of gene expression in the
Courtial, Nadine   +5 more
core   +9 more sources

Structural Analysis of (p)ppGpp Reveals Its Versatile Binding Pattern for Diverse Types of Target Proteins

open access: yesFrontiers in Microbiology, 2020
(p)ppGpp, highly phosphorylated guanosine, are global regulatory nucleotides that modulate several biochemical events in bacterial physiology ranging from core central dogma to various metabolic pathways.
Gajraj Singh Kushwaha   +3 more
doaj   +1 more source

Adaptation with transcriptional regulation [PDF]

open access: yesScientific Reports, 2017
AbstractBiochemical adaptation is one of the basic functions that are widely implemented in biological systems for a variety of purposes such as signal sensing, stress response and homeostasis. The adaptation time scales span from milliseconds to days, involving different regulatory machineries in different processes.
Shi, Wenjia   +4 more
openaire   +4 more sources

Contrasting roles for G-quadruplexes in regulating human Bcl-2 and virus homologues KSHV KS-Bcl-2 and EBV BHRF1

open access: yesScientific Reports, 2022
Herpesviruses are known to acquire several genes from their hosts during evolution. We found that a significant proportion of virus homologues encoded by HSV-1, HSV-2, EBV and KSHV and their human counterparts contain G-quadruplex motifs in their ...
Shivani Kumar   +6 more
doaj   +1 more source

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