Results 21 to 30 of about 4,117,946 (252)

An effective strategy for identifying autogenous regulation of transcription factors in filamentous fungi

Microbiology Spectrum, 2023
Transcription factors (TFs) play a crucial role in regulating gene expression in living organisms, and any malfunction in their functions can lead to severe physiological consequences.
Longguang Qin, Shuhui Guo, Ang Li, Lu Fan, Kaeling Tan, Koon Ho Wong   +5 more
doaj   +1 more source

Transcription- and regulation-related genes that were significantly regulated in type 2 diabetic patient skin samples.

, 2020
Transcription- and regulation-related genes that were significantly regulated in type 2 diabetic patient skin samples.
Annette Graham (793627), Jeff Auster (8479050), Po-Chih Chen (456126), Adrianne Spencer (8479047), Eri Takematsu (4775088), Patricia Martin (41047), Aaron B. Baker (8479053)   +6 more
core   +1 more source

The Fission Yeast Homeodomain Protein Yox1p Binds to MBF and Confines MBF-Dependent Cell-Cycle Transcription to G1-S via Negative Feedback [PDF]

, 2009
The regulation of the G1- to S-phase transition is critical for cell-cycle progression. This transition is driven by a transient transcriptional wave regulated by transcription factor complexes termed MBF/SBF in yeast and E2F-DP in mammals. Here we apply
Brazma Alvis, Klier, S, Codlin, S, Lackner Daniel H., Bahler, J, Alvis Brazma, Brian T Wilhelm, Robertus A M de Bruin, Sofia Aligianni, de Bruin, RAM, Daniel H Lackner, Sandra Codlin, Gabriella Rustici, Klier Steffi, Wilhelm, BT, Rustici Gabriella, Lackner, DH, Marguerat Samuel, Aligianni, S, Bähler Jürg, de Bruin, RA, Jürg Bähler, Brazma, A, Codlin Sandra, Marguerat, S, Steffi Klier, Wilhelm Brian T., Samuel Marguerat, Aligianni Sofia, de Bruin Robertus A. M., Rustici, G   +30 more
core   +1 more source

The function of the protein phosphatase Glc7p in transcription termination, RNA processing and transcriptional regulation of ribosomal protein genes [PDF]

, 2007
Gene transcription in general can be subdivided into three main phases: transcription initiation, elongation and termination. The enzyme that accomplishes transcription of protein coding genes, snRNAs and snoRNAs is RNA polymerase II (RNAP II).
Röck, Salome
core   +1 more source

Positive and negative regulation of Myc-mediated transcription [PDF]

, 2008
The aim of this thesis has been focused to analyze the positive regulation of Myc-mediated transcription by P-TEFb elongation complex, and the negative control exerted by p14ARF onco-suppressor on Myc's transactivation functions.
Gargano, Barbara
core   +1 more source

dKDM5/LID regulates H3K4me3 dynamics at the transcription-start site (TSS) of actively transcribed developmental genes [PDF]

, 2012
H3K4me3 is a histone modification that accumulates at the transcription-start site (TSS) of active genes and is known to be important for transcription activation.
Ponsà-Cobas, Joan, Azorín, F., Azorín, Ferran, Sílvia Pérez-Lluch, Tomás Morán, Morán, Tomás, David Rossell, Lloret-Llinares, Marta, Joan Ponsa-Cobas, Rossell, David, Herbert Auer, Azorín, Fernando, Fernando Azorín, Marta Lloret-Llinares, Pérez-Lluch, Sílvia, Corominas, Montserrat, Montserrat Corominas, Auer, Herbert, Corominas, Montserrat (Corominas Guiu)   +18 more
core   +1 more source

The Nuclear Lamina as an Organizer of Chromosome Architecture

Cells, 2019
The nuclear lamina (NL) is a meshwork of lamins and lamin-associated proteins adjoining the inner side of the nuclear envelope. In early embryonic cells, the NL mainly suppresses background transcription, whereas, in differentiated cell types, its ...
Yuri Y. Shevelyov, Sergey V. Ulianov
doaj   +1 more source

Evaluation of seaweed sulfated polysaccharides as natural antagonists targeting Salmonella typhi OmpF: molecular docking and pharmacokinetic profiling

Beni-Suef University Journal of Basic and Applied Sciences, 2022
Background Salmonella belongs to the Enterobacteriaceae family, a gram-negative, non-spore-forming, rod-shaped, motile, and pathogenic bacteria that transmit through unhygienic conditions.
Malaisamy Arunkumar, Murugan Mahalakshmi, Vairamuthu Ashokkumar, Manikka Kubendran Aravind, Sathaiah Gunaseelan, Verma Mohankumar, Balasubramaniem Ashokkumar, Perumal Varalakshmi   +7 more
doaj   +1 more source

Role of FlhF and its domains in the assembly of a polar flagellum in P. aeruginosa

Journal of Bacteriology
FlhF, an SRP GTPase, regulates the polarity and flagellation patterns in various bacteria, including Pseudomonas aeruginosa. FlhF is a multidomain protein that comprises three domains: B, N, and G, or the GTPase domain.
Shikha Raghav, Rohit Prajapati, Deepti Jain   +2 more
doaj   +1 more source

Structures of the Ets Protein DNA-binding Domains of Transcription Factors Etv1, Etv4, Etv5, and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation. [PDF]

, 2015
Ets transcription factors, which share the conserved Ets DNA-binding domain, number nearly 30 members in humans and are particularly involved in developmental processes.
Allerston, Charles K., Gileadi, Opher, Cooper, Christopher D.O., Newman, Joseph A., Aitkenhead, Hazel   +4 more
core   +1 more source