Results 11 to 20 of about 4,117,946 (252)

Modelling transcriptional regulation with a mixture of factor analyzers and variational Bayesian expectation maximization [PDF]

, 2009
Understanding the mechanisms of gene transcriptional regulation through analysis of high-throughput postgenomic data is one of the central problems of computational systems biology.
Husmeier, D., Lin, K.
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Analysis of G-quadruplexes upstream of herpesvirus miRNAs: evidence of G-quadruplex mediated regulation of KSHV miR-K12–1-9,11 cluster and HCMV miR-US33

BMC Molecular and Cell Biology, 2020
Background G-quadruplexes regulate gene expression, recombination, packaging and latency in herpesviruses. Herpesvirus-encoded miRNAs have been linked to important biological functions. The presence and the biological role of G-quadruplexes have not been
Shivani Kumar, Divya Choudhary, Anupam Patra, Neel Sarovar Bhavesh, Perumal Vivekanandan   +4 more
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Towards molecular systems biology of gene transcription and regulation [PDF]

, 2010
Ten years after the determination of the RNA polymerase 11 structure, the basic mechanism of mRNA synthesis during gene transcription is known. In the future, the initiation and regulation of transcription must be studied with a combination of structural
Cramer, P., Cramer, Patrick, Cramer, Patrick (author)   +2 more
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Structural basis of copper-efflux-regulator-dependent transcription activation

iScience, 2021
Summary: The copper efflux regulator (CueR), a representative member of mercury resistance regulator (MerR) family metalloregulators, controls expression of copper homeostasis-regulating genes in bacteria.
Wei Shi, Baoyue Zhang, Yanan Jiang, Chang Liu, Wei Zhou, Ming Chen, Yang Yang, Yangbo Hu, Bin Liu   +8 more
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An R2R3 MYB transcription factor associated with regulation of the anthocyanin biosynthetic pathway in Rosaceae [PDF]

, 2010
Background The control of plant anthocyanin accumulation is via transcriptional regulation of the genes encoding the biosynthetic enzymes. A key activator appears to be an R2R3 MYB transcription factor.
Wang, Kui-Lin, Kortstee, A.J., Tony K McGhie, McGhie Tony K, Hellens, R.P., Espley Richard V, Hellens Roger P, Grafton, Karryn, Espley, Richard V., Karryn Grafton, Karunairetnam, Sakuntala, Andrew C Allan, Kortstee, Anne, Roger P Hellens, Allan, A.C., Allan, Andrew C., McGhie, T.K., Richard V Espley, Kortstee Anne, Allan Andrew C, Espley, R.V., Sakuntala Karunairetnam, Karunairetnam Sakuntala, Grafton Karryn, McGhie, Tony K., Lin-Wang Kui, Bolitho, Karen, Karen Bolitho, Anne Kortstee, Bolitho Karen, Hellens, Roger P., Lin-Wang, Kui, Kui Lin-Wang   +32 more
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Structural visualization of transcription activated by a multidrug-sensing MerR family regulator

Nature Communications, 2021
The MerR family of transcriptional regulators, such as EcmrR, activate promoters with a structure that is suboptimal for recognition by RNA polymerase holoenzyme. Structural insights into the EcmrR-dependent transcription process elucidate the mechanisms
Yang Yang, Chang Liu, Wei Zhou, Wei Shi, Ming Chen, Baoyue Zhang, David G. Schatz, Yangbo Hu, Bin Liu   +8 more
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Transcription regulation of the Escherichia coli pcnB gene coding for poly(A) polymerase I: roles of ppGpp, DksA and sigma factors [PDF]

, 2010
Poly(A) polymerase I (PAP I), encoded by the pcnB gene, is a major enzyme responsible for RNA polyadenylation in Escherichia coli, a process involved in the global control of gene expression in this bacterium through inXuencing the rate of transcript ...
Grzegorz Węgrzyn, Monika Słomińska-Wojewódzka, Nadratowska-Wesołowska, Beata, Węgrzyn, Alicja, Węgrzyn, Grzegorz, Słomińska-Wojewódzka, Monika, Agnieszka Szalewska-Pałasz, Beata Nadratowska-Wesołowska, Robert Łyżeń, Alicja Węgrzyn, Łyżeń, Robert, Szalewska-Pałasz, Agnieszka   +11 more
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TRIMER: Transcription Regulation Integrated with Metabolic Regulation

iScience, 2021
Summary: There has been extensive research in predictive modeling of genome-scale metabolic reaction networks. Living systems involve complex stochastic processes arising from interactions among different biomolecules.
Puhua Niu, Maria J. Soto, Byung-Jun Yoon, Edward R. Dougherty, Francis J. Alexander, Ian Blaby, Xiaoning Qian   +6 more
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Nucleosome-mediated cooperativity between transcription factors [PDF]

, 2009
Cooperative binding of transcription factors (TFs) to cis-regulatory regions (CRRs) is essential for precision of gene expression in development and other processes.
Leonid A. Mirny, Mirny, Leonid A
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Dia2 controls transcription by mediating assembly of the RSC complex. [PDF]

, 2011
BACKGROUND: Dia2 is an F-box protein found in the budding yeast, S. cerevisiae. Together with Skp1 and Cul1, Dia2 forms the substrate-determining part of an E3 ubiquitin ligase complex, otherwise known as the SCF.
Yu Veronica P. C. C., Veronica P. C. C. Yu, Yu, VPCC, Kessler, BM, Andress Edward J., Edelmann, MJ, Benedikt M. Kessler, Holic, R, Edelmann Mariola J., Mariola J Edelmann, Edelmann, Mariola J., Kessler Benedikt M., Mariola J. Edelmann, Yu, Veronica P. C. C., Holic, Roman, Andress, Edward J., Kessler, Benedikt M., Veronica P C C Yu, Benedikt M Kessler, Holic Roman, Edward J Andress, Roman Holic, Andress, EJ, Edward J. Andress   +23 more
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