Results 21 to 30 of about 5,538,535 (384)
Heliyon, 2023 Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer and accounts for about 95% of all head and neck cancers with high mortality, usually at a late stage.
Bolaji Fatai Oyeyemi +6 more
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GTRD: an integrated view of transcription regulation
Nucleic Acids Res., 2020 The Gene Transcription Regulation Database (GTRD; http://gtrd.biouml.org/) contains uniformly annotated and processed NGS data related to gene transcription regulation: ChIP-seq, ChIP-exo, DNase-seq, MNase-seq, ATAC-seq and RNA-seq.
S. Kolmykov +8 more
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Structural basis of copper-efflux-regulator-dependent transcription activation
iScience, 2021 Summary: The copper efflux regulator (CueR), a representative member of mercury resistance regulator (MerR) family metalloregulators, controls expression of copper homeostasis-regulating genes in bacteria.
Wei Shi +8 more
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BMC Molecular and Cell Biology, 2020 Background G-quadruplexes regulate gene expression, recombination, packaging and latency in herpesviruses. Herpesvirus-encoded miRNAs have been linked to important biological functions. The presence and the biological role of G-quadruplexes have not been
Shivani Kumar +4 more
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Dynamics of transcriptional and post-transcriptional regulation [PDF]
Briefings in Bioinformatics, 2020 AbstractDespite gene expression programs being notoriously complex, RNA abundance is usually assumed as a proxy for transcriptional activity. Recently developed approaches, able to disentangle transcriptional and post-transcriptional regulatory processes, have revealed a more complex scenario.
Furlan M, De Pretis S, Pelizzola M
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Structural visualization of transcription activated by a multidrug-sensing MerR family regulator
Nature Communications, 2021 The MerR family of transcriptional regulators, such as EcmrR, activate promoters with a structure that is suboptimal for recognition by RNA polymerase holoenzyme. Structural insights into the EcmrR-dependent transcription process elucidate the mechanisms
Yang Yang +8 more
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TRIMER: Transcription Regulation Integrated with Metabolic Regulation
iScience, 2021 Summary: There has been extensive research in predictive modeling of genome-scale metabolic reaction networks. Living systems involve complex stochastic processes arising from interactions among different biomolecules.
Puhua Niu +6 more
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Transcriptional Regulation of Osteoblasts [PDF]
Cells Tissues Organs, 2007 The differentiation of osteoblasts from mesenchymal precursors requires a series of cell fate decisions controlled by a hierarchy of transcription factors. These include RUNX2, Osterix (OSX), ATF4 and a large number of nuclear coregulators. During bone development, initial RUNX2 expression coincides with the formation of mesenchymal condensations and ...
Franceschi, Renny T. +4 more
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Information on Transcriptional Regulation and Signal Transduction of _Escherichia coli_ K-12 Integrated in the Database RegulonDB. [PDF]
, 2010 Since its inception, RegulonDB ("http://regulondb.ccg.unam.mx/":http://regulondb.ccg.unam.mx/) has been a database that compiles information about the regulation of transcription initiation of _Escherichia coli_ K-12. However, we are aware that
Alberto Santos-Zavaleta +7 more
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Microbiology Spectrum, 2023 Transcription factors (TFs) play a crucial role in regulating gene expression in living organisms, and any malfunction in their functions can lead to severe physiological consequences.
Longguang Qin +5 more
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