Results 51 to 60 of about 5,538,535 (384)
Foods, 2022 During fermentation and food processing, Lacticaseibacillus rhamnosus ATCC 53103 can encounter many adverse conditions, and acid stress is one of them.
Xuejing Fan +7 more
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Regulation of Transcript Elongation [PDF]
Annual Review of Microbiology, 2015 Bacteria lack subcellular compartments and harbor a single RNA polymerase that synthesizes both structural and protein-coding RNAs, which are cotranscriptionally processed by distinct pathways. Nascent rRNAs fold into elaborate secondary structures and associate with ribosomal proteins, whereas nascent mRNAs are translated by ribosomes.
Irina Artsimovitch, Georgiy A. Belogurov
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Extending the dynamic range of transcription factor action by translational regulation
, 2015 A crucial step in the regulation of gene expression is binding of transcription factor (TF) proteins to regulatory sites along the DNA. But transcription factors act at nanomolar concentrations, and noise due to random arrival of these molecules at their
Bialek, William +3 more
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Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrepresented upstream motifs [PDF]
, 2004 BACKGROUND: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition motifs located upstream of the coding region of the regulated gene.
Caselle, Michele +4 more
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Spatial clustering and common regulatory elements correlate with coordinated gene expression [PDF]
, 2019 Many cellular responses to surrounding cues require temporally concerted transcriptional regulation of multiple genes. In prokaryotic cells, a single-input-module motif with one transcription factor regulating multiple target genes can generate ...
Bai, Fan +6 more
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Towards molecular systems biology of gene transcription and regulation [PDF]
, 2010 Ten years after the determination of the RNA polymerase 11 structure, the basic mechanism of mRNA synthesis during gene transcription is known. In the future, the initiation and regulation of transcription must be studied with a combination of structural
Cramer, Patrick
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Transcriptional Regulators of Angiogenesis [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2006 Angiogenesis, the process by which new blood vessels develop from a pre-existing vascular network, is essential for normal development and in certain physiological states. Inadequate or excessive angiogenesis has been incriminated in a number of pathologic states.
Anne Hamik, Baiqiu Wang, Mukesh K. Jain
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Frontiers in Immunology, 2021 The human SFTPA1 and SFTPA2 genes encode the surfactant protein A1 (SP-A1) and SP-A2, respectively, and they have been identified with significant genetic and epigenetic variability including sequence, deletion/insertions, and splice variants.
Joanna Floros +2 more
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Structure of the measles virus ternary polymerase complex
Nature CommunicationsMeasles virus (MeV) is a highly contagious pathogen that causes significant morbidity worldwide. Its polymerase machinery, composed of the large protein (L) and phosphoprotein (P), is crucial for viral replication and transcription, making it a promising
Dong Wang, Ge Yang, Bin Liu
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DoGFinder: a software for the discovery and quantification of readthrough transcripts from RNA-seq
BMC Genomics, 2018 Background Recent studies have described a widespread induction of transcriptional readthrough as a consequence of various stress conditions in mammalian cells.
Yuval Wiesel, Niv Sabath, Reut Shalgi
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