Results 41 to 50 of about 990,842 (289)
The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure genome stability [PDF]
, 2012 Bidirectionally moving DNA replication forks merge at termination sites composed of accidental or programmed DNA-protein barriers. If merging fails, then regions of unreplicated DNA can result in the breakage of DNA during mitosis, which in turn can give
Steinacher, R. +14 more
core +1 more source
Nature Communications, 2023 Transcription termination is an essential and dynamic process that can tune gene expression in response to diverse molecular signals. Yet, the genomic positions, molecular mechanisms, and regulatory consequences of termination have only been studied ...
Emily Petroni +5 more
doaj +1 more source
An Allosteric Path to Transcription Termination [PDF]
Molecular Cell, 2007 Transcription termination signals in bacteria occur in RNA as a strong hairpin followed by a stretch of U residues at the 3' terminus. To release the transcript, RNA polymerase (RNAP) is thought to translocate forward without RNA synthesis.
Epshtein, Vitaly +4 more
openaire +2 more sources
Nature Communications, 2021 Termination of eukaryotic RNA polymerase III (Pol III)-mediated transcription occurs when the polymerase reaches a stretch of four or more deoxythymidine nucleotides (poly-dT) on the non-template strand.
Haifeng Hou +7 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2019 Accurate and efficient transcription termination is an important step for cells to generate functional RNA transcripts. In bacteria, two mechanisms are responsible for terminating transcription: intrinsic (Rho-independent) termination and Rho-dependent ...
Jiandong Chen +3 more
doaj +1 more source
Transcription termination and antitermination of bacterial CRISPR arrays
eLife, 2020 A hallmark of CRISPR-Cas immunity systems is the CRISPR array, a genomic locus consisting of short, repeated sequences (‘repeats’) interspersed with short, variable sequences (‘spacers’). CRISPR arrays are transcribed and processed into individual CRISPR
Anne M Stringer +4 more
doaj +1 more source
Scientific Reports, 2023 The DNA damage response (DDR) is an evolutionarily conserved process essential for cell survival. The transcription changes triggered by DDR depend on the nature of DNA damage, activation of checkpoint kinases, and the stage of cell cycle.
Pritpal Kaur +4 more
doaj +1 more source
Mobile call termination in the UK [PDF]
, 2007 We discuss policy towards mobile call termination, illustrated by the 2002 Competition Commission enquiry into the UK mobile market. We present a model of the mobile market which includes both fixed-to-mobile and mobile-to-mobile call termination.
Wright, J. +5 more
core +1 more source
Cell Reports, 2014 Current models of transcription termination factor recruitment to the RNA polymerase II (Pol II) transcription complex rely exclusively on the direct interaction between the termination factor and phosphorylated isoforms of the Pol II C-terminal domain ...
Erika Pearson, Claire Moore
doaj +1 more source
The Transcription Unit Architecture of Streptomyces lividans TK24
Frontiers in Microbiology, 2019 Streptomyces lividans is an attractive host for production of heterologous proteins and secondary metabolites of other Streptomyces species. To fully harness the industrial potential of S.
Yongjae Lee +10 more
doaj +1 more source