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Transcriptional regulation [PDF]
EMBO reports, 2008 Overall, the meeting provided an excellent environment for those interested in transcriptional regulation to interact and to hear about a diverse array of topics, which stimulated lively discussions from the interdisciplinary audience. It was a consensus opinion that the meeting was a great success and it is hoped that the keystone symposia will ...
Jan Tuckermann, Peter Herrlich
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Transcriptional regulation [PDF]
WormBook, 2005 The regulation of transcription in C. elegans shares many similarities to transcription in other organisms. The details of how specific transcription factors bind to target promoters and act as either activators or repressors are still being examined in many cases, but an increasing number of factors and their binding sites are being characterized ...
Peter G, Okkema, Michael, Krause
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The Roles of RUNX Proteins in Lymphocyte Function and Anti-Tumor Immunity
Cells, 2022 The Runt-related transcription factor (RUNX) family of proteins are crucial for many developmental and immuno-physiological processes. Their importance in cellular and tissue development has been repeatedly demonstrated as they are often found mutated ...
Wooseok Seo +2 more
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Optical Clearing and Light Sheet Microscopy Imaging of Amphioxus
Frontiers in Cell and Developmental Biology, 2021 Cephalochordates (amphioxi or lancelets) are representatives of the most basally divergent group of the chordate phylum. Studies of amphioxus development and anatomy hence provide a key insight into vertebrate evolution.
Simona Machacova +4 more
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miRNAs Regulate miRNAs: Coordinated Transcriptional and Post-Transcriptional Regulation [PDF]
Cell Cycle, 2006 microRNAs are short single-stranded RNA molecules that negatively regulate gene expression at post-transcriptional level. Recently it has been demonstrated that microRNAs are involved in many physiological processes, including differentiation and development.
Tuccoli A, Poliseno L, Rainaldi G
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Transcriptional regulation of haematopoietic transcription factors [PDF]
Stem Cell Research & Therapy, 2011 The control of differential gene expression is central to all metazoan biology. Haematopoiesis represents one of the best understood developmental systems where multipotent blood stem cells give rise to a range of phenotypically distinct mature cell types, all characterised by their own distinctive gene expression profiles.
Wilson, Nicola K +3 more
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Impaired tissue homing by the Ikzf3N159S variant is mediated by interfering with Ikaros function
Frontiers in Immunology, 2023 AIOLOS, encoded by IKZF3, is a member of the IKZF family of proteins that plays an important role in regulating late B-cell differentiation. Human individuals heterozygous for the AIOLOS p.N160S variant displayed impaired humoral immune responses as well
Jingjie Chang +5 more
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Cells, 2023 Chromatin remodeling complexes are required for many distinct nuclear processes such as transcription, DNA replication, and DNA repair. However, the contribution of these complexes to the development of complex tissues within an organism is poorly ...
Andrea Kuzelova +8 more
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A lens-specific co-injection marker for medaka transgenesis
BioTechniques, 2010 Recent advances in generating transgenic fish have improved the efficiency of germline transmission and enabled the generation of large numbers of transgenic animals.
Pavel Vopalensky +3 more
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Wnt/β-catenin signaling is an evolutionarily conserved determinant of chordate dorsal organizer
eLife, 2020 Deciphering the mechanisms of axis formation in amphioxus is a key step to understanding the evolution of chordate body plan. The current view is that Nodal signaling is the only factor promoting the dorsal axis specification in the amphioxus, whereas ...
Iryna Kozmikova, Zbynek Kozmik
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