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Transcriptional Regulation in Bacteria [PDF]
MicroorganismsThe goal of research in the post-genomic era, now that the full extent of the genes encoded on microbial genomes is known [https://www [...]
Tomohiro Shimada
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Transcriptional Regulation of Inflammasomes [PDF]
International Journal of Molecular Sciences, 2020 Inflammasomes are multimolecular complexes with potent inflammatory activity. As such, their activity is tightly regulated at the transcriptional and post-transcriptional levels.
M. Cornut, E. Bourdonnay, T. Henry
semanticscholar +5 more sources
Roles of XBP1s in Transcriptional Regulation of Target Genes
Biomedicines, 2021 The spliced form of X-box binding protein 1 (XBP1s) is an active transcription factor that plays a vital role in the unfolded protein response (UPR). Under endoplasmic reticulum (ER) stress, unspliced Xbp1 mRNA is cleaved by the activated stress sensor ...
Sung-Min Park, Tae-Il Kang, Jae-Seon So
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The Roles of RUNX Proteins in Lymphocyte Function and Anti-Tumor Immunity
Cells, 2022 The Runt-related transcription factor (RUNX) family of proteins are crucial for many developmental and immuno-physiological processes. Their importance in cellular and tissue development has been repeatedly demonstrated as they are often found mutated ...
Wooseok Seo +2 more
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Optical Clearing and Light Sheet Microscopy Imaging of Amphioxus
Frontiers in Cell and Developmental Biology, 2021 Cephalochordates (amphioxi or lancelets) are representatives of the most basally divergent group of the chordate phylum. Studies of amphioxus development and anatomy hence provide a key insight into vertebrate evolution.
Simona Machacova +4 more
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Multiplexed CRISPR technologies for gene editing and transcriptional regulation
Nature Communications, 2020 Multiplexed CRISPR technologies, in which numerous gRNAs or Cas enzymes are expressed at once, have facilitated powerful biological engineering applications, vastly enhancing the scope and efficiencies of genetic editing and transcriptional regulation ...
Nicholas S. McCarty +3 more
semanticscholar +1 more source
Transcriptional regulation of DC fate specification [PDF]
, 2020 Dendritic cells function in the immune system to instruct adaptive immune cells to respond accordingly to different threats. While conventional dendritic cells can be subdivided into two main subtypes, termed cDC1s and cDC2s, it is clear that further ...
Bosteels, Cedric, Scott, Charlotte
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Impaired tissue homing by the Ikzf3N159S variant is mediated by interfering with Ikaros function
Frontiers in Immunology, 2023 AIOLOS, encoded by IKZF3, is a member of the IKZF family of proteins that plays an important role in regulating late B-cell differentiation. Human individuals heterozygous for the AIOLOS p.N160S variant displayed impaired humoral immune responses as well
Jingjie Chang +5 more
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Cells, 2023 Chromatin remodeling complexes are required for many distinct nuclear processes such as transcription, DNA replication, and DNA repair. However, the contribution of these complexes to the development of complex tissues within an organism is poorly ...
Andrea Kuzelova +8 more
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The Role of Transcriptional Regulation in Hybrid Vigor
Frontiers in Plant Science, 2020 The genetic basis of hybrid vigor in plants remains largely unsolved but strong evidence suggests that variation in transcriptional regulation can explain many aspects of this phenomenon. Natural variation in transcriptional regulation is highly abundant
Ramon Botet, J. Keurentjes
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