Results 1 to 10 of about 1,358,415 (326)

Transcriptional Regulation in Bacteria [PDF]

Microorganisms
The goal of research in the post-genomic era, now that the full extent of the genes encoded on microbial genomes is known [https://www [...]
Tomohiro Shimada
doaj   +2 more sources

Transcriptional regulation of neuropeptide receptors underlies context-dependent adaptation in Drosophila melanogaster. [PDF]

FEBS Open Bio
Ryu S, Wei Y, Wu Z, Zhang T, Lee D, Najafi H, Kim WJ.   +6 more
europepmc   +3 more sources

The Roles of RUNX Proteins in Lymphocyte Function and Anti-Tumor Immunity

Cells, 2022
The Runt-related transcription factor (RUNX) family of proteins are crucial for many developmental and immuno-physiological processes. Their importance in cellular and tissue development has been repeatedly demonstrated as they are often found mutated ...
Wooseok Seo, Aneela Nomura, Ichiro Taniuchi   +2 more
doaj   +1 more source

Optical Clearing and Light Sheet Microscopy Imaging of Amphioxus

Frontiers in Cell and Developmental Biology, 2021
Cephalochordates (amphioxi or lancelets) are representatives of the most basally divergent group of the chordate phylum. Studies of amphioxus development and anatomy hence provide a key insight into vertebrate evolution.
Simona Machacova, Helena Chmelova, Anna Vavrova, Zbynek Kozmik, Iryna Kozmikova   +4 more
doaj   +1 more source

Impaired tissue homing by the Ikzf3N159S variant is mediated by interfering with Ikaros function

Frontiers in Immunology, 2023
AIOLOS, encoded by IKZF3, is a member of the IKZF family of proteins that plays an important role in regulating late B-cell differentiation. Human individuals heterozygous for the AIOLOS p.N160S variant displayed impaired humoral immune responses as well
Jingjie Chang, Motoi Yamashita, Motoi Yamashita, Aditya K. Padhi, Kam Y. J. Zhang, Ichiro Taniuchi   +5 more
doaj   +1 more source

Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell Proliferation and Photoreceptor Maintenance

Cells, 2023
Chromatin remodeling complexes are required for many distinct nuclear processes such as transcription, DNA replication, and DNA repair. However, the contribution of these complexes to the development of complex tissues within an organism is poorly ...
Andrea Kuzelova, Naoko Dupacova, Barbora Antosova, Sweetu Susan Sunny, Zbynek Kozmik, Jan Paces, Arthur I. Skoultchi, Tomas Stopka, Zbynek Kozmik   +8 more
doaj   +1 more source

Wnt/β-catenin signaling is an evolutionarily conserved determinant of chordate dorsal organizer

eLife, 2020
Deciphering the mechanisms of axis formation in amphioxus is a key step to understanding the evolution of chordate body plan. The current view is that Nodal signaling is the only factor promoting the dorsal axis specification in the amphioxus, whereas ...
Iryna Kozmikova, Zbynek Kozmik
doaj   +1 more source

A lens-specific co-injection marker for medaka transgenesis

BioTechniques, 2010
Recent advances in generating transgenic fish have improved the efficiency of germline transmission and enabled the generation of large numbers of transgenic animals.
Pavel Vopalensky, Jana Ruzickova, Barbora Pavlu, Zbynek Kozmik   +3 more
doaj   +1 more source

Runx-mediated regulation of CCL5 via antagonizing two enhancers influences immune cell function and anti-tumor immunity

Nature Communications, 2020
CCL5 is an important chemokine for modulation of inflammatory responses, but how CCL5 expression is regulated is still unclear. Here the authors show that the CCL5 locus contains two enhancers, with the proximal enhancer being responsible for homeostatic
Wooseok Seo, Kanako Shimizu, Satoshi Kojo, Arinze Okeke, Terumi Kohwi-Shigematsu, Shin-ichiro Fujii, Ichiro Taniuchi   +6 more
doaj   +1 more source

Nascent RNA sequencing reveals mechanisms of gene regulation in the human malaria parasite Plasmodium falciparum. [PDF]

, 2017
Gene expression in Plasmodium falciparum is tightly regulated to ensure successful propagation of the parasite throughout its complex life cycle. The earliest transcriptomics studies in P.
Batugedara, Gayani, Bunnik, Evelien M, Le Roch, Karine G, Lee, Michael, Lu, Xueqing Maggie, Prudhomme, Jacques   +5 more
core   +1 more source