Results 21 to 30 of about 1,358,415 (326)
Runx-dependent and silencer-independent repression of a maturation enhancer in the Cd4 gene
Nature Communications, 2018 The commitment of helper and cytotoxic lineages for CD4 and CD8 T cells, respectively, is associated with the regulation of Cd4 gene expression. Here the authors show that an intronic silencer, S4, has differential effects and synergy with the RUNX ...
Satoshi Kojo +4 more
doaj +1 more source
LSD1 Facilitates Pro-Inflammatory Polarization of Macrophages by Repressing Catalase
Cells, 2021 The increased level of hydrogen peroxide accompanies some modes of macrophage specification and is linked to ROS-based antimicrobial activity of these phagocytes.
Maciej Sobczak +5 more
doaj +1 more source
Circadian rhythms and post-transcriptional regulation in higher plants [PDF]
, 2015 The circadian clock of plants allows them to cope with daily changes in their environment. This is accomplished by the rhythmic regulation of gene expression, in a process that involves many regulatory steps.
Romanowski, Andrés +1 more
core +3 more sources
Nature Communications, 2019 The original version of this Article contained an error in the author affiliations. Affiliation 5 incorrectly read ‘Laboratory for Prediction of Cell Systems Dynamics, RIKEN Center for Biosystems Dynamics Research (BDR), Suite, Hyogo 565-0874, Japan ...
Chizuko Miyamoto +7 more
doaj +1 more source
Challenges and Advances in the Taxonomy of Deep-Sea Peracarida: From Traditional to Modern Methods
Frontiers in Marine Science, 2022 As one of the oldest branches of biology, taxonomy deals with the identification, classification and naming of living organisms, using a variety of tools to explore traits at the morphological and molecular level.
Inmaculada Frutos +6 more
doaj +1 more source
Transcriptional regulation of DC fate specification [PDF]
, 2020 Dendritic cells function in the immune system to instruct adaptive immune cells to respond accordingly to different threats. While conventional dendritic cells can be subdivided into two main subtypes, termed cDC1s and cDC2s, it is clear that further ...
Bosteels, Cedric, Scott, Charlotte
core +1 more source
Nature Communications, 2019 Group 2 innate lymphoid cells (ILC2) are important mediators for allergy, but how ILC2 are regulated under chronic inflammation is still unclear. Here the authors show that Runx transcription factors, which normally suppresses ILC2 activation at steady ...
Chizuko Miyamoto +7 more
doaj +1 more source
The Distinctive Regulation of Cyanobacterial Glutamine Synthetase [PDF]
, 2018 Glutamine synthetase (GS) features prominently in bacterial nitrogen assimilation as it catalyzes the entry of bioavailable nitrogen in form of ammonium into cellular metabolism. The classic example, the comprehensively characterized GS of enterobacteria,
Bolay, Paul +3 more
core +1 more source
Novel Insights into the Molecular Mechanisms Governing Embryonic Epicardium Formation
Journal of Cardiovascular Development and Disease, 2023 The embryonic epicardium originates from the proepicardium, an extracardiac primordium constituted by a cluster of mesothelial cells. In early embryos, the embryonic epicardium is characterized by a squamous cell epithelium resting on the myocardium ...
Rita Carmona +6 more
doaj +1 more source
HTRIdb: an open-access database for experimentally verified human transcriptional regulation interactions [PDF]
, 2012 Background: The modeling of interactions among transcription factors (TFs) and their respective target genes (TGs) into transcriptional regulatory networks is important for the complete understanding of regulation of biological processes.
Luiz A. Bovolenta +2 more
core +4 more sources