Results 21 to 30 of about 4,769,934 (397)

Transcriptional Regulation of Osteoblasts [PDF]

Cells Tissues Organs, 2007
The differentiation of osteoblasts from mesenchymal precursors requires a series of cell fate decisions controlled by a hierarchy of transcription factors. These include RUNX2, Osterix (OSX), ATF4 and a large number of nuclear coregulators. During bone development, initial RUNX2 expression coincides with the formation of mesenchymal condensations and ...
Franceschi, Renny T., Ge, Chunxi, Xiao, Guozhi, Roca, Hernan, Jiang, Di   +4 more
openaire   +7 more sources

A lens-specific co-injection marker for medaka transgenesis

BioTechniques, 2010
Recent advances in generating transgenic fish have improved the efficiency of germline transmission and enabled the generation of large numbers of transgenic animals.
Pavel Vopalensky, Jana Ruzickova, Barbora Pavlu, Zbynek Kozmik   +3 more
doaj   +1 more source

Wnt/β-catenin signaling is an evolutionarily conserved determinant of chordate dorsal organizer

eLife, 2020
Deciphering the mechanisms of axis formation in amphioxus is a key step to understanding the evolution of chordate body plan. The current view is that Nodal signaling is the only factor promoting the dorsal axis specification in the amphioxus, whereas ...
Iryna Kozmikova, Zbynek Kozmik
doaj   +1 more source

Transcriptional Regulation: a Genomic Overview [PDF]

, 2002
The availability of the Arabidopsis thaliana genome sequence allows a comprehensive analysis of transcriptional regulation in plants using novel genomic approaches and methodologies. Such a genomic view of transcription first necessitates the compilation
Riechmann, José Luis
core   +2 more sources

The role of input noise in transcriptional regulation [PDF]

, 2007
Even under constant external conditions, the expression levels of genes fluctuate. Much emphasis has been placed on the components of this noise that are due to randomness in transcription and translation; here we analyze the role of noise associated ...
A Bar–Even, AA Verveen, AA Verveen, AM Walczak, C Zhao, CF Stevens, DS Burz, E Ozbudak, E Schneidman, F Conti, FJ Sigworth, FJ Sigworth, Gašper Tkačik, H Lecar, H Lecar, HB Barlow, HB Barlow, HC Berg, I Golding, J Paulsson, J Reinitz, JM Pedraza, JM Raser, JR Newman, JS van Zon, M Ptashne, MB Elowitz, N Rosenfeld, P Fatt, P Fatt, PS Swain, PV Pedone, RL Winston, Rory Edward Morty, S Hecht, S Hooshangi, SE Luria, T Gregor, T Gregor, Thomas Gregor, W Bialek, W Bialek, W Bialek, W Bialek, William Bialek, WJ Blake, X Ma   +46 more
core   +16 more sources

Regulation of HPV transcription

Clinics, 2018
Human papillomavirus infection is associated with the development of malignant and benign neoplasms. Approximately 40 viral types can infect the anogenital mucosa and are categorized into high- and low-risk oncogenic human papillomavirus, depending on their association with the development of cervical carcinoma. High-risk human papillomavirus 16 and 18
Ribeiro, Aline Lopes, Caodaglio, Amanda Schiersner, Sichero, Laura   +2 more
openaire   +5 more sources

Nascent RNA sequencing reveals mechanisms of gene regulation in the human malaria parasite Plasmodium falciparum. [PDF]

, 2017
Gene expression in Plasmodium falciparum is tightly regulated to ensure successful propagation of the parasite throughout its complex life cycle. The earliest transcriptomics studies in P.
Batugedara, Gayani, Bunnik, Evelien M, Le Roch, Karine G, Lee, Michael, Lu, Xueqing Maggie, Prudhomme, Jacques   +5 more
core   +1 more source

Delayed puberty, gonadotropin abnormalities and subfertility in male Padi2/Padi4 double knockout mice

Reproductive Biology and Endocrinology, 2022
Background Peptidylarginine deiminase enzymes (PADs) convert arginine residues to citrulline in a process called citrullination or deimination. Recently, two PADs, PAD2 and PAD4, have been linked to hormone signaling in vitro and the goal of this study ...
Kelly L. Sams, Chinatsu Mukai, Brooke A. Marks, Chitvan Mittal, Elena Alina Demeter, Sophie Nelissen, Jennifer K. Grenier, Ann E. Tate, Faraz Ahmed, Scott A. Coonrod   +9 more
doaj   +1 more source

Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet

Nature Communications, 2020
Metabolic adaptation to different diets results in changes to gene expression. Here, the authors characterise the chromatin landscape and transcriptional network in mice on a diet of high saturated fat, compared to a diet high in carbohydrate, finding a ...
Yufeng Qin, Sara A. Grimm, John D. Roberts, Kaliopi Chrysovergis, Paul A. Wade   +4 more
doaj   +1 more source

Transcriptional downregulation of agr expression in Staphylococcus aureus during growth in human serum can be overcome by constitutively active mutant forms of the sensor kinase AgrC [PDF]

, 2013
The temporal and cell density-dependent regulation of expression of virtually all the Staphylococcus aureus virulon is under the control of the agr (accessory gene regulatory) operon.
Edwards, AM, James, EH, Wigneshweraraj, S   +2 more
core   +1 more source