Results 151 to 160 of about 181,971 (294)
At the Pointy End of Mechanobiology: AFM for Transient Biomechanical Analysis
Advanced Healthcare Materials, EarlyView.Stem cell mechanosensitivity governs lineage commitment through mechanotransduction, but capturing these transient changes in living cells remains challenging. Advanced atomic force microscopy enables high‐resolution analysis of mechanical properties, real‐time protein distribution, and gene expression, offering fresh insights into cell‐environment ...
Kaiwen Zhang +5 more
wiley +1 more source
Scientific ReportsLimited knowledge currently exists regarding the shared genetic architecture influencing human cognitive ability-related traits. We utilized Genomic Structural Equation Modeling (Genomic-SEM) along with multiple post-GWAS methods to estimate potentially ...
Haifeng Chen +5 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.A simplified, co‐culture‐free protocol for kidney organoids that generate segmented nephrons, including collecting ducts, has been developed. Early low‐dose RA with FGF9 induces balanced anterior–posterior IM patterning and dual UE/MM lineage commitment. BMP7 enhances nephron progenitor maturation.
Jung Hwa Lim +13 more
wiley +1 more source
Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials
Advanced Healthcare Materials, EarlyView.The production of recombinant proteins represents a fundamental step in the characterisation of marine invertebrate adhesives and in the development of bio‐inspired glues. The association of these proteins with other components such as ions, proteins, polysaccharides, or polymers enables the fabrication of biomaterials for various healthcare ...
Alessandra Whaite +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash +4 more
wiley +1 more source
A multi‐omics analysis reveals candidate genes for Cd tolerance in Paspalum vaginatum
BMC Plant BiologyCadmium (Cd) pollution in the farmland has become a serious global issue threatening both human health and plant biomass production. Seashore paspalum (Paspalum vaginatum Sw.), a halophytic turfgrass, has been recognized as a Cd-tolerant species. However,
Xu Hu +13 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim +16 more
wiley +1 more source
Large-scale transcriptome-wide association study identifies new prostate cancer risk regions [PDF]
, 2018 Nicholas Mancuso +73 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda +1 more
wiley +1 more source