Results 51 to 60 of about 39,970,022 (174)
Communications Biology, 2022 Calwing Liao and Veikko Vuokila et al. report a transcriptome-wide association study (TWAS) of Tourette’s Syndrome. They find increased expression of FLT3 in the dorsolateral prefrontal cortex and the lymphoblastoid cell lines in patients with Tourette’s
Calwing Liao +8 more
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A cross-tissue transcriptome association study identifies key genes in essential hypertension
Frontiers in Genetics, 2023 Genome-wide association study (GWAS) have identified over 1,000 loci associated with blood pressure. However, these loci only explain 6% of heritability. Transcriptome-wide association studies (TWAS) combine GWAS summary data with expression quantitative
Sihui Huang +14 more
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Nature Communications, 2018 Genetic loci linked to susceptibility for the common skin cancer cutaneous squamous cell carcinoma (cSCC) have been identified by genome wide association studies (GWAS).
Nilah M. Ioannidis +8 more
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Frontiers in Genetics, 2021 Anxiety disorders are common mental disorders that often result in disability. Recently, large-scale genome-wide association studies (GWASs) have identified several novel risk variants and loci for anxiety disorders (or anxiety traits). Nevertheless, how
Xi Su +13 more
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, 2021 Sweet corn is consistently one of the most highly consumed vegetables in the U.S., providing a valuable opportunity to increase nutrient intake through biofortification.
University of Georgia (17856095)
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Multi-tissue transcriptome-wide association studies. [PDF]
, 2020 A transcriptome-wide association study (TWAS) attempts to identify disease associated genes by imputing gene expression into a genome-wide association study (GWAS) using an expression quantitative trait loci (eQTL) data set and then testing for ...
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Large-scale transcriptome-wide association study identifies new prostate cancer risk regions
Nature Communications, 2018 Genome-wide association studies (GWAS) have identified hundreds of genomic risk regions for prostate cancer. Here, the authors perform a transcriptome wide association study (TWAS) by incorporating prostate cancer GWAS with gene expression data to ...
Nicholas Mancuso +10 more
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Power Analysis of Transcriptome-Wide Association Studies (TWAS)
, 2020 Association studies between genetic variants and complex traits are popular and valuable in both genetic and clinical fields. Among all kinds of studies proposed, transcriptome-wide association studies (TWAS) have become influential and widely used. In my thesis, I focus on revealing under which settings of genetic parameters and architectures, TWAS ...
openaire +2 more sources
Transcriptome-Wide Association Supplements Genome-Wide Association in Zea mays [PDF]
, 2019 Modern improvement of complex traits in agricultural species relies on successful associations of heritable molecular variation with observable phenotypes. Historically, this pursuit has primarily been based on easily measurable genetic markers.
Gore, Michael A +4 more
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Assigning function to genome wide association study variants associated with complex gastrointestinal disease [PDF]
, 2009 PhDThe genome‐wide association study era has identified numerous loci associated with many common polygenic diseases. The next challenge is to identify the functional consequences of these variants and elicit how they impact on disease risk.
Heap, Graham Alastair Richard
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