Results 41 to 50 of about 654,399 (276)

Analysis of Global Gene Expression in Maize (Zea mays) Vegetative and Reproductive Tissues That Differ in Accumulation of Starch and Sucrose

Plants, 2022
Carbon allocation between vegetative and reproductive tissues impacts cereal grain production. Despite great agricultural importance, sink–source relationships have not been fully characterized at the early reproductive stages in maize. Here, we quantify
Cristal López-González, Sheila Juárez-Colunga, Samuel Trachsel, Nayelli Marsch-Martínez, C. Stewart Gillmor, Axel Tiessen   +5 more
doaj   +1 more source

Perturbations in neuroinflammatory pathways are associated with paclitaxel-induced peripheral neuropathy in breast cancer survivors. [PDF]

, 2019
Paclitaxel is a common chemotherapy drug associated with the development of chronic paclitaxel-induced peripheral neuropathy (PIPN). PIPN is associated with neuroinflammatory mechanisms in pre-clinical studies.
Abrams, Gary, Chesney, Margaret, Conley, Yvette P, Kober, Kord M, Levine, Jon D, Melisko, Michelle, Miaskowski, Christine, Paul, Steven M, Schumacher, Mark, Topp, Kimberly   +9 more
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Quantitative Proteome and Transcriptome Dynamics Analysis Reveals Iron Deficiency Response Networks and Signature in Neuronal Cells

Molecules, 2022
Iron and oxygen deficiencies are common features in pathophysiological conditions, such as ischemia, neurological diseases, and cancer. Cellular adaptive responses to such deficiencies include repression of mitochondrial respiration, promotion of ...
Luke Erber, Shirelle Liu, Yao Gong, Phu Tran, Yue Chen   +4 more
doaj   +1 more source

FreePSI: an alignment-free approach to estimating exon-inclusion ratios without a reference transcriptome. [PDF]

, 2017
Alternative splicing plays an important role in many cellular processes of eukaryotic organisms. The exon-inclusion ratio, also known as percent spliced in, is often regarded as one of the most effective measures of alternative splicing events.
Jiang, Tao, Ma, Shining, Wang, Dongfang, Zeng, Jianyang, Zhou, Jianyu   +4 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Transcriptome Analysis Reveals the Resistance Mechanism of Pseudomonas aeruginosa to Tachyplesin I

Infection and Drug Resistance, 2020
Jun Hong, 1, 2 Honghao Jiang, 1 Jianye Hu, 1 Lianzhe Wang, 1 Ruifang Liu 1 1College of Life Science and Engineering, Henan University of Urban Construction, Ping Dingshan 467036, People’s Republic of China; 2Henan Province Key Laboratory of Water
Hong J, Jiang H, Hu J, Wang L, Liu R
doaj  

Correcting Differential Gene Expression Analysis for Cyto—Architectural Alterations in Substantia Nigra of Parkinson’s Disease Patients Reveals Known and Potential Novel Disease—Associated Genes and Pathways

Cells, 2022
Several studies have analyzed gene expression profiles in the substantia nigra to better understand the pathological mechanisms causing Parkinson’s disease (PD).
Federico Ferraro, Christina Fevga, Vincenzo Bonifati, Wim Mandemakers, Ahmed Mahfouz, Marcel Reinders   +5 more
doaj   +1 more source

Transcriptome analysis of Azospirillum lipoferum during its interaction with rice [PDF]

, 2012
The associative symbiosis between Plant Growth Promoting Rhizobacteria of the genus Azospirillum and cereals have mainly been studied from an agronomic and economic point of view, and several studies showed that plant morphological and metabolic changes ...
Borland, Stéphanie, Drogue, Benoit, Prigent-Combaret, Claire, Sanguin, Hervé, Wisniewski-Dyé, Florence   +4 more
core  

Advancing transcriptome platforms [PDF]

, 2011
During the last decade of years, remarkable technological innovations have emerged that allow the direct or indirect determination of the transcriptome at unprecedented scale and speed.
Shuobo Shi
core   +2 more sources