Results 31 to 40 of about 380,258 (247)
Single-cell transcriptomics reveals cell-type-specific diversification in human heart failure
Heart failure represents a major cause of morbidity and mortality worldwide. Single-cell transcriptomics have revolutionized our understanding of cell composition and associated gene expression.
Andrew L. Koenig+13 more
semanticscholar +1 more source
Making open data work for plant scientists [PDF]
Despite the clear demand for open data sharing, its implementation within plant science is still limited. This is, at least in part, because open data-sharing raises several unanswered questions and challenges to current research practices.
Alsheikh-Ali+24 more
core +1 more source
Background The expected increase in global surface temperature due to climate change may have a tremendous effect on the structure and function of the anaerobic food web in flooded rice field soil.
Jingjing Peng+4 more
doaj +1 more source
Cost effective, experimentally robust differential-expression analysis for human/mammalian, pathogen and dual-species transcriptomics. [PDF]
As sequencing read length has increased, researchers have quickly adopted longer reads for their experiments. Here, we examine 14 pathogen or host-pathogen differential gene expression data sets to assess whether using longer reads is warranted.
Bruno, Vincent M+9 more
core +2 more sources
Maternal recognition of pregnancy in the horse : are MicroRNAs the secret messengers? [PDF]
The signal for maternal recognition of pregnancy (MRP) has still not been identified in the horse. High-throughput molecular biology at the embryo-maternal interface has substantially contributed to the knowledge on pathways affected during MRP, but an ...
Deforce, Dieter+11 more
core +2 more sources
Modeling population size independent tissue epigenomes by ChIL‐seq with single thin sections
Recent advances in genome‐wide technologies have enabled analyses using small cell numbers of even single cells. However, obtaining tissue epigenomes with cell‐type resolution from large organs and tissues still remains challenging, especially when the ...
Kazumitsu Maehara+11 more
doaj +1 more source
A high NH4+ load is known to inhibit bacterial methane oxidation. This is due to a competition between CH4 and NH3 for the active site of particulate methane monooxygenase (pMMO), which converts CH4 to CH3OH.
Kangli Guo+4 more
doaj +1 more source
Spatially Informed Cell Type Deconvolution for Spatial Transcriptomics
Many spatially resolved transcriptomic technologies do not have single-cell resolution but measure the average gene expression for each spot from a mixture of cells of potentially heterogeneous cell types.
Ying Ma, Xiang Zhou
semanticscholar +1 more source
Complex Systems Science: Dreams of Universality, Reality of Interdisciplinarity [PDF]
Using a large database (~ 215 000 records) of relevant articles, we empirically study the "complex systems" field and its claims to find universal principles applying to systems in general. The study of references shared by the papers allows us to obtain
Bastian M.+9 more
core +4 more sources
The Envelope (E) Protein of SARS-CoV-2 as a Pharmacological Target
The COVID-19 pandemic caused by the SARS-CoV-2 virus is still a global health concern. Several spike (S) protein-based vaccines have been developed that efficiently protect the human population against severe forms of COVID-19.
Teresa Santos-Mendoza
doaj +1 more source