Results 41 to 50 of about 299,908 (313)
Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy [PDF]
, 2017 Mechanisms underlying the onset and progression of nephropathy in diabetic patients are not fully elucidated. Deregulation of proteolytic systems is a known path leading to disease manifestation, therefore we hypothesized that proteases aberrantly ...
Bascands, Jean-Loup +15 more
core +2 more sources
HTLV-1 contains a high CG dinucleotide content and is susceptible to the host antiviral protein ZAP
Retrovirology, 2019 Background Human T cell leukaemia virus type 1 (HTLV-1) is a retrovirus associated with human diseases such as adult T-cell leukaemia/lymphoma and HTLV-1 associated myelopathy/tropical spastic paraparesis.
Paola Miyazato +8 more
doaj +1 more source
Biomolecules, 2023 Human T-cell leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL). HTLV-1 carriers have a lifelong asymptomatic balance between infected cells and host antiviral immunity; however, 5–10% of carriers lose this balance and develop ATL.
Shingo Nakahata +4 more
doaj +1 more source
Inferring spatial and signaling relationships between cells from single cell transcriptomic data. [PDF]
, 2020 Single-cell RNA sequencing (scRNA-seq) provides details for individual cells; however, crucial spatial information is often lost. We present SpaOTsc, a method relying on structured optimal transport to recover spatial properties of scRNA-seq data by ...
Cang, Zixuan, Nie, Qing
core
Deep generative modeling for single-cell transcriptomics. [PDF]
, 2018 Single-cell transcriptome measurements can reveal unexplored biological diversity, but they suffer from technical noise and bias that must be modeled to account for the resulting uncertainty in downstream analyses.
A Regev +39 more
core +1 more source
Scientific Reports, 2022 Chili (Capsicum annuum L.) and brinjal (Solanum melongena L.) are the most widely grown solanaceous crops in the world. However, their production has reduced over several years due to the attack of various fungal and bacterial pathogens and various ...
Tasmeen J. Parihar +13 more
doaj +1 more source
, 2018 Transcriptomics, the study of RNA molecules, provides in-depth understanding of cellular functions and the genomic landscape of transcription. Transcriptomics refers to the study of all classes on RNA molecules including mRNA, tRNA, and siRNA. In this chapter, we specifically focus on mRNA, which encodes the protein-coding portion of the genomic DNA ...
Singan, Vasanth R +2 more
openaire +4 more sources
Comparative genomics and transcriptomics of Escherichia coli isolates carrying virulence factors of both enteropathogenic and enterotoxigenic E. coli [PDF]
, 2017 Escherichia coli that are capable of causing human disease are often classified into pathogenic variants (pathovars) based on their virulence gene content. However, disease-associated hybrid E.
Daugherty, Sean C +6 more
core +2 more sources
BcCluster: a bladder cancer database at the molecular level [PDF]
, 2016 Background: Bladder Cancer (BC) has two clearly distinct phenotypes. Non-muscle invasive BC has good prognosis and is treated with tumor resection and intravesical therapy whereas muscle invasive BC has poor prognosis and requires usually systemic ...
Bhat, Akshay +5 more
core +3 more sources
Enabling precision medicine in neonatology, an integrated repository for preterm birth research [PDF]
, 2018 Preterm birth, or the delivery of an infant prior to 37 weeks of gestation, is a significant cause of infant morbidity and mortality. In the last decade, the advent and continued development of molecular profiling technologies has enabled researchers to ...
Chubiz, Jessica +2 more
core +5 more sources