Results 61 to 70 of about 320,395 (368)
Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics
BMC Genomics, 2017 Single-cell transcriptomics allows researchers to investigate complex communities of heterogeneous cells. It can be applied to stem cells and their descendants in order to chart the progression from multipotent progenitors to fully differentiated cells ...
Kelly Street +7 more
semanticscholar +1 more source
Nucleic Acids Research, 2023 Recent technological developments in spatial transcriptomics allow researchers to measure gene expression of cells and their spatial locations at the single-cell level, generating detailed biological insight into biological processes.
Zhicheng Xu +29 more
semanticscholar +1 more source
SpaceTx: A Roadmap for Benchmarking Spatial Transcriptomics Exploration of the Brain [PDF]
arXiv, 2023 Mapping spatial distributions of transcriptomic cell types is essential to understanding the brain, with its exceptional cellular heterogeneity and the functional significance of its spatial organization. Spatial transcriptomics techniques are hoped to accomplish these measurements, but each method uses different experimental and computational ...
arxiv
Comparative Genomics and Transcriptomics To Analyze Fruiting Body Development in Filamentous Ascomycetes. [PDF]
, 2019 Many filamentous ascomycetes develop three-dimensional fruiting bodies for production and dispersal of sexual spores. Fruiting bodies are among the most complex structures differentiated by ascomycetes; however, the molecular mechanisms underlying this ...
Barry, Kerrie +13 more
core +1 more source
Microbiological Research, 2007 We have now entered in the post-genomic era, where we have knowledge of plethora of fungal genomes and cutting edge technology is available to study global mRNA, protein and metabolite profiles. These so-called 'omic' technologies (transcriptomics, proteomics and metabolomics) provide the possibility to characterize plant-pathogen interactions and ...
Bhadauria, Vijai +3 more
openaire +2 more sources
Frontiers in Molecular Neuroscience, 2016 Amyotrophic lateral sclerosis (ALS) is a progressive fatal multisystemic neurodegenerative disorder caused by preferential degeneration of upper and lower motor neurons.
Stefanie Krüger +15 more
doaj +1 more source
Inferring spatial and signaling relationships between cells from single cell transcriptomic data. [PDF]
, 2020 Single-cell RNA sequencing (scRNA-seq) provides details for individual cells; however, crucial spatial information is often lost. We present SpaOTsc, a method relying on structured optimal transport to recover spatial properties of scRNA-seq data by ...
Cang, Zixuan, Nie, Qing
core
High-throughput transcriptomics
Scientific Reports, 2022 High-throughput transcriptomics has revolutionised the field of transcriptome research by offering a cost-effective and powerful screening tool. Standard bulk RNA sequencing (RNA-Seq) enables characterisation of the average expression profiles for individual samples and facilitates identification of the molecular functions associated with genes ...
Nunzio D’Agostino +2 more
openaire +4 more sources
Scientific Reports, 2022 Chili (Capsicum annuum L.) and brinjal (Solanum melongena L.) are the most widely grown solanaceous crops in the world. However, their production has reduced over several years due to the attack of various fungal and bacterial pathogens and various ...
Tasmeen J. Parihar +13 more
doaj +1 more source
Quantitative RNA-seq Analysis Unveils Osmotic and Thermal Adaptation Mechanisms Relevant for Ectoine Production in Chromohalobacter salexigens [PDF]
, 2018 Quantitative RNA sequencing (RNA-seq) and the complementary phenotypic assays were implemented to investigate the transcriptional responses of Chromohalobacter salexigens to osmotic and heat stress.
Carmen Vargas +6 more
core +2 more sources