Results 71 to 80 of about 398,969 (379)
Emerging studies demonstrate the ability of microRNAs (miRNAs) to activate genes via different mechanisms. Specifically, miRNAs may trigger an enhancer promoting chromatin remodelling in the enhancer region, thus activating the enhancer and its target ...
Anna Elizarova+3 more
doaj +1 more source
Diatom Proteomics Reveals Unique Acclimation Strategies to Mitigate Fe Limitation [PDF]
Phytoplankton growth rates are limited by the supply of iron (Fe) in approximately one third of the open ocean, with major implications for carbon dioxide sequestration and carbon (C) biogeochemistry.
Boyd, Philip W.+7 more
core +1 more source
Recent advances in spatially resolved transcriptomics have enabled comprehensive measurements of gene expression patterns while retaining the spatial context of the tissue microenvironment.
Kangning Dong, Shihua Zhang
semanticscholar +1 more source
Standards and infrastructure for managing experimental metadata [PDF]
*See also the "related presentation":http://precedings.nature.com/documents/3145/version/1* We present an infrastructure that leverages synergistic reporting standards and ontologies^1,2,3,4,5^ to create a common structured ...
Chris Taylor+7 more
core +2 more sources
Identifying spatial domain by adapting transcriptomics with histology through contrastive learning
Recent advances in spatial transcriptomics have enabled measurements of gene expression at cell/spot resolution meanwhile retaining both the spatial information and the histology images of the tissues.
Yuansong Zeng+7 more
semanticscholar +1 more source
BcCluster: a bladder cancer database at the molecular level [PDF]
Background: Bladder Cancer (BC) has two clearly distinct phenotypes. Non-muscle invasive BC has good prognosis and is treated with tumor resection and intravesical therapy whereas muscle invasive BC has poor prognosis and requires usually systemic ...
Bhat, Akshay+5 more
core +3 more sources
Human Pulmonary Tuberculosis: Understanding the Immune Response in the Bronchoalveolar System
Mycobacterium tuberculosis, the causal agent of one of the most devastating infectious diseases worldwide, can evade or modulate the host immune response and remain dormant for many years. In this review, we focus on identifying the local immune response
María Teresa Herrera+6 more
doaj +1 more source
Characterization of key triacylglycerol biosynthesis processes in rhodococci. [PDF]
Oleaginous microorganisms have considerable potential for biofuel and commodity chemical production. Under nitrogen-limitation, Rhodococcus jostii RHA1 grown on benzoate, an analog of lignin depolymerization products, accumulated triacylglycerols (TAGs ...
Amara, Sawsan+5 more
core +2 more sources
Spatial transcriptomics is a newly emerging field that enables high‐throughput investigation of the spatial localization of transcripts and related analyses in various applications for biological systems.
Han-Eol Park+8 more
semanticscholar +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source