Results 81 to 90 of about 398,969 (379)

A decade of pollen transcriptomics [PDF]

open access: yesPlant Reproduction, 2015
Overview of pollen transcriptome studies. Pollen development is driven by gene expression, and knowledge of the molecular events underlying this process has undergone a quantum leap in the last decade through studies of the transcriptome. Here, we outline historical evidence for male haploid gene expression and review the wealth of pollen transcriptome
Rutley, N., Twell, David
openaire   +4 more sources

The acute phase reactant orosomucoid-2 directly promotes rheumatoid inflammation

open access: yesExperimental and Molecular Medicine
Acute phase proteins involved in chronic inflammatory diseases have not been systematically analyzed. Here, global proteome profiling of serum and urine revealed that orosomucoid-2 (ORM2), an acute phase reactant, was differentially expressed in ...
Ki-Myo Kim   +7 more
doaj   +1 more source

Integrative omics analysis of Pseudomonas aeruginosa virus PA5oct highlights the molecular complexity of jumbo phages [PDF]

open access: yes, 2020
Pseudomonas virus vB_PaeM_PA5oct is proposed as a model jumbo bacteriophage to investigate phage-bacteria interactions and is a candidate for phage therapy applications.
Blasdel, Bob G.   +9 more
core   +1 more source

Spatial transcriptomics reveal neuron–astrocyte synergy in long-term memory

open access: yesNature
Memory encodes past experiences, thereby enabling future plans. The basolateral amygdala is a centre of salience networks that underlie emotional experiences and thus has a key role in long-term fear memory formation1.
Wenfei Sun   +7 more
semanticscholar   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Systems analysis of host-parasite interactions. [PDF]

open access: yes, 2015
Parasitic diseases caused by protozoan pathogens lead to hundreds of thousands of deaths per year in addition to substantial suffering and socioeconomic decline for millions of people worldwide.
Jamshidi, Neema   +3 more
core   +1 more source

Spatial transcriptomics stratifies psoriatic disease severity by emergent cellular ecosystems

open access: yesScience immunology, 2023
Whereas the cellular and molecular features of human inflammatory skin diseases are well characterized, their tissue context and systemic impact remain poorly understood.
R. Castillo   +24 more
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Totipotency of mouse zygotes extends to single blastomeres of embryos at the four-cell stage

open access: yesScientific Reports, 2021
In multicellular organisms, oocytes and sperm undergo fusion during fertilization and the resulting zygote gives rise to a new individual. The ability of zygotes to produce a fully formed individual from a single cell when placed in a supportive ...
Marino Maemura   +7 more
doaj   +1 more source

Transcriptomic effects of the non-steroidal anti-inflammatory drug Ibuprofen in the marine bivalve Mytilus galloprovincialis Lam [PDF]

open access: yes, 2016
The transcriptomic effects of Ibuprofen (IBU) in the digestive gland tissue of Mytilus galloprovincialis Lam. specimens exposed at low environmental concentrations (250 ng L-1) are presented. Using a 1.7 K feature cDNA microarray along with linear models
Amorim, Monica J. B.   +3 more
core   +1 more source

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