Results 131 to 140 of about 152,119 (385)

Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han   +5 more
wiley   +1 more source

Globular and Fibrous Proteins Modified with Deep Eutectic Solvents: Materials for Drug Delivery

open access: yesMolecules, 2019
Proteinaceous materials have numerous structures, many of which aid in the roles they perform. Some need to impart strength while others need elasticity or toughness.
Wanwan Qu   +4 more
doaj   +1 more source

Drug crystallization – implications for topical and transdermal delivery [PDF]

open access: yes, 2016
INTRODUCTION: Crystallization of actives in skin following topical application was suggested by studies in the 1950s and 1960s but is poorly understood.
Hadgraft, J, Lane, ME
core   +1 more source

Low‐Temperature Fabrication of Thymosin β4‐Loaded Soluble Microneedles to Promote Wound Healing by Specific Binding to Downregulated Immune Regulators Vsig4 and IL22rɑ2

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He   +4 more
wiley   +1 more source

Iontophoretic and Microneedle Mediated Transdermal Delivery of Glycopyrrolate

open access: yesPharmaceutics, 2014
Purpose: The objective of this study was to investigate the use of iontophoresis, soluble microneedles and their combination for the transdermal delivery of glycopyrrolate.
Meera Gujjar, Ajay K. Banga
doaj   +1 more source

General practitioners' reasons for removing patients from their lists: postal survey in England and Wales [PDF]

open access: yes, 2001
The removal of patients from doctors' lists causes con­ siderable public and political concern, with speculation that patients are removed for inappropriate, including financial, reasons.
Munro, J.F.   +3 more
core   +2 more sources

Electro‐Stimulated Graphene‐Polymer Nanocomposites Enable Wearable Patches With Feedback‐Controlled Drug Release

open access: yesAdvanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Stimuli‐responsive nanomaterials capable of spatiotemporal control over drug release are of nanocomposite patch (“e‐Medi‐Patch”) engineered from biodegradable polycaprolactone (PCL), graphene nanoplatelets, and a redox‐active therapeutic, niclosamide. The hierarchical composite integrates π‐π interactions between aromatic drug molecules
Santosh K. Misra   +7 more
wiley   +1 more source

Wearable Enzymatic Alcohol Biosensor

open access: yesSensors, 2019
Transdermal alcohol biosensors have the ability to detect the alcohol that emanates from the bloodstream and diffuses through the skin. However, previous biosensors have suffered from long-term fouling of the sensor element and drift in the resulting ...
Bob Lansdorp   +3 more
doaj   +1 more source

Vesicular systems for delivering conventional small organic molecules and larger macromolecules to and through human skin [PDF]

open access: yes, 2009
The history of using vesicular systems for drug delivery to and through skin started nearly three decades ago with a study utilizing phospholipid liposomes to improve skin deposition and reduce systemic effects of triamcinolone acetonide.
El Maghraby, Gamal M.   +1 more
core   +1 more source

Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain

open access: yesAdvanced Materials, EarlyView.
A novel carbon quantum dots‐dissolvable microneedle, CQDs‐dMN system, enables painless delivery and real‐time tracking of HSV‐1. The HSV‐1 is labeled with fluorescent CQDs and delivered to the skin dermis, minimizing damage compared to traditional methods.
Yaxiu Feng   +11 more
wiley   +1 more source

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