Results 131 to 140 of about 141,563 (385)

Low‐Temperature Fabrication of Thymosin β4‐Loaded Soluble Microneedles to Promote Wound Healing by Specific Binding to Downregulated Immune Regulators Vsig4 and IL22rɑ2

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He   +4 more
wiley   +1 more source

Dendrimers for Drug Delivery

open access: yesMolecules, 2018
Dendrimers have come a long way in the last 25 years since their inception. Originally created as a wonder molecule of chemistry, dendrimer is now in the fourth class of polymers. Dr.
Abhay Singh Chauhan
doaj   +1 more source

Deformable Nanovesicles Synthesized through an Adaptable Microfluidic Platform for Enhanced Localized Transdermal Drug Delivery. [PDF]

open access: yes, 2017
Phospholipid-based deformable nanovesicles (DNVs) that have flexibility in shape offer an adaptable and facile method to encapsulate diverse classes of therapeutics and facilitate localized transdermal delivery while minimizing systemic exposure. Here we
Alam, Mohammad Parvez   +7 more
core   +2 more sources

Electro‐Stimulated Graphene‐Polymer Nanocomposites Enable Wearable Patches With Feedback‐Controlled Drug Release

open access: yesAdvanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Stimuli‐responsive nanomaterials capable of spatiotemporal control over drug release are of nanocomposite patch (“e‐Medi‐Patch”) engineered from biodegradable polycaprolactone (PCL), graphene nanoplatelets, and a redox‐active therapeutic, niclosamide. The hierarchical composite integrates π‐π interactions between aromatic drug molecules
Santosh K. Misra   +7 more
wiley   +1 more source

Globular and Fibrous Proteins Modified with Deep Eutectic Solvents: Materials for Drug Delivery

open access: yesMolecules, 2019
Proteinaceous materials have numerous structures, many of which aid in the roles they perform. Some need to impart strength while others need elasticity or toughness.
Wanwan Qu   +4 more
doaj   +1 more source

Transdermal delivery of testosterone [PDF]

open access: yes, 2015
Male hypogonadism has been treated with exogenous testosterone since the 1930s. The early transdermal patches of testosterone became available in the 1980s with gel and solution preparations following subsequent decades.
Hadgraft, J, Lane, ME
core   +1 more source

Colloidal Heterostructures Enable Interfacial Transport of Immiscible Molecules in Printable Organohydrogels

open access: yesAdvanced Materials, EarlyView.
Multiphase printable organohydrogels with tunable microstructures are developed to control molecular transport pathways for immiscible cargo. The tortuosity and domain size of the colloidal phases are tuned by adjusting temperature and shear during processing, which enables the tailoring of diffusion kinetics due to different transport pathways.
Riley E. Dowdy‐Green   +4 more
wiley   +1 more source

Iontophoretic and Microneedle Mediated Transdermal Delivery of Glycopyrrolate

open access: yesPharmaceutics, 2014
Purpose: The objective of this study was to investigate the use of iontophoresis, soluble microneedles and their combination for the transdermal delivery of glycopyrrolate.
Meera Gujjar, Ajay K. Banga
doaj   +1 more source

Drug crystallization – implications for topical and transdermal delivery [PDF]

open access: yes, 2016
INTRODUCTION: Crystallization of actives in skin following topical application was suggested by studies in the 1950s and 1960s but is poorly understood.
Hadgraft, J, Lane, ME
core   +1 more source

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

open access: yesAdvanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon   +21 more
wiley   +1 more source

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