Results 121 to 130 of about 23,063 (265)

Unveiling the Microvasculature: The Index of Microcirculatory Resistance and Its Expanding Role in Cardiovascular Care

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Index of microcirculatory resistance (IMR) is a cutting‐edge, wire‐based tool that advances the capability assessment of coronary microvascular function. By utilizing distal coronary pressure and mean transit time under maximal hyperemia, IMR delivers consistent, reproducible insights into the microvasculature's dynamic health.
Joanna Sohn, Matthew A. Soderstrom, Ariana Ramirez, John‐Henry Dean, Raj Shah, Debanshu Roy, Kenneth Stone, Ariel Vinas, Bryan Ramsey, Charles Lin, Robert Chilton   +10 more
wiley   +1 more source

Core-Sheath Nanofibers From a Modified Coaxial Electrospinning for Transdermal Delivery of Finasteride. [PDF]

ChemistryOpen
Sun L, Zhao Y, Caomeng X, Yu DG, Liu P.
europepmc   +1 more source

Single Centre Experience With the Balloon‐Expandable Myval Transcatheter Aortic Valve System in Patients With Bicuspid Anatomy: 1 Year Follow‐Up

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Transcatheter aortic valve implantation (TAVI) in bicuspid aortic valve (BAV) anatomy remains challenging due to anatomical complexity and limited trial data. New‐generation balloon‐expandable valves, such as Myval, require further evaluation in this subgroup.
Balázs Magyari, Bálint Kittka, Ilona Goják, Gábor Kasza, Kristóf Schönfeld, László Botond Szapáry, Mihály Simon, Rudolf Kiss, Andrea Bertalan, Edit Várady, István Szokodi, Iván Horváth   +11 more
wiley   +1 more source

Clinical and Echocardiographic Outcomes After Implantation of the ALLEGRA Transcatheter Valve Using the Fully Repositionable IMPERIA Delivery System: One‐Year Results of the EMPIRE I Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The EMPIRE I study assessed the early (30 days) safety and efficacy of a new fully repositionable delivery system (IMPERIA) for the commercially available ALLEGRA transcatheter aortic valve in patients with either severe native aortic stenosis or a degenerated surgical bioprosthesis.
José Antonio Baz, Claire B. Ren, Christof Burgdorf, Christian Frerker, Ignacio Cruz‐González, Joan Antoni Gómez, José Maria Hernândez, Pilar Jimenez, Ernest Spitzer, Pim Tonino, Pieter Vriesendorp, Nicolas van Mieghem, Samuel Copt, Anders Jönsson, Keith G. Oldroyd, Nicolas Doll   +15 more
wiley   +1 more source

Mechanistic Modelling of Transdermal Delivery Dependence on Drug Properties. [PDF]

Pharm Res
Benbrook N, Zhan W.
europepmc   +1 more source

Percutaneous Deployment of the Sinus‐SuperFlex‐DS Stent for Hybrid Stage I Palliation in Neonates Weighing ≤ 2.5 kg: A Multicenter Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Hybrid stage I palliation (HS1P) has developed as an alternative to the Norwood stage I palliation for neonates with hypoplastic left heart and related left‐sided obstructive lesions. HS1P is currently used in various clinical settings, such as single ventricle palliation, bridge to decision, bridge to biventricular repair, or ...
Johanna Hummel, Jochen Grohmann, Katarzyna Gendera, Götz Müller, Harald Bertram, Matthias Sigler, Dietmar Schranz, Christian Jux, Markus Khalil   +8 more
wiley   +1 more source

Advancements in Therapeutic Deep Eutectic Solvents as Multifunctional Transdermal Delivery Systems. [PDF]

Pharmaceutics
Li K, Yan B, Cao Z, Lu R, Wu G, Hai Y.
europepmc   +1 more source

Pathophysiologic Consequences of Early Coarctation Stenting in a Longitudinal Porcine Model

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Novel stent technologies offer early intravascular treatment options for coarctation (COA). Mid‐to‐long‐term cardiovascular responses to early COA stent interventions are undefined. Aims We studied a porcine model of COA, with and without early stent implantation with serial dilation to adult aortic diameters, aiming to define ...
Leah M. Gober, Michael A. Stellon, Matt A. Culver, Amy Frenkel, Dana Irrer, Colleen M. Witzenburg, Alejandro Roldán‐Alzate, Luke Lamers   +7 more
wiley   +1 more source

Transdermal Delivery of Chinese Medicinal Formula Mitigates Pediatric Constipation by Modulating Intestinal Endocrine and Metabolic Homeostasis. [PDF]

Biomater Res
Song F, Ren Y, Zhu M, Liu Y, Wei S, Li H, Peng L.   +6 more
europepmc   +1 more source

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

Clinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary, Robert Bies, Osei Boateng, Rachel Daley, Pierre Gashema, Mili Karina, Emily Njuguna, Sharon Nachman, Nathaniel Nkrumah, Carolyne Odula, Andrew Owen, Ethel D. Weld, Prajith Venkatasubramanian, Adeniyi Olagunju, on behalf of the Community of Practice for Long‐acting Therapeutics for Maternal and Paediatric Health, Rana Abutaima, Dorothy Akongo, Abdulnaser Alsharaa, Moherndran Archary, Shakir Atoyebi, Benoit Bestgen, Robert Bies, Osei Boateng, Andrew Butler, Edmund Capparelli, Rachel Daley, Layla Davies, Joelle Dountio, Henry Enzama, Pierre Gashema, Katila George, Dan Hawcutt, Rene Holm, Patrick Gad Iradukunda, Elodie Jambert, Mili Karina, Linda Lewis, Grace Miheso, Sebastien Morin, Andrew Morrison, Sharon Nachman, Shadia Nakalema, Emily Njunga, Nathaniel Nkrumah, Carolyne Odula‐Obonyo, Brenda Okware, Adeniyi Olagunju, Andrew Owen, Martina Penazzato, Natella Rakhmanina, Mphako Brighton Ratlabyana, Rachel Scott, Kimberly Struble, Andre‐Marie Tchouatieu, Catherine Unsworth, Prajith Venkatasubramanian, Catriona Waitt, Ethel Weld, Janine Winterbottom, Leena Zino   +59 more
wiley   +1 more source